6SWY

Structure of active GID E3 ubiquitin ligase complex minus Gid2 and delta Gid9 RING domain

Summary for 6SWY

• Entry DOI: 10.2210/pdb6swy/pdb
• EMDB information: 10326 10327 10328 10329 10330 10331 10332 10333
• Descriptor: Vacuolar import and degradation protein 28, Glucose-induced degradation protein 8, Vacuolar import and degradation protein 30,Vacuolar import and degradation protein 30,Vacuolar import and degradation protein 30,Vacuolar import and degradation protein 30,Vacuolar import and degradation protein 30,Vacuolar import and degradation protein 30,Vacuolar import and degradation protein 30,Vacuolar import and degradation protein 30,Vacuolar import and degradation protein 30,Vacuolar import and degradation protein 30,Vacuolar import and degradation protein 30,Vacuolar import and degradation protein 30,Vacuolar import and degradation protein 30,Vacuolar import and degradation protein 30,Vacuolar import and degradation protein 30,Vacuolar import and degradation protein 30, ... (5 entities in total)
• Functional Keywords: suppressed, suppreseed, ligase
• Biological source: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast); More
• Total number of polymer chains: 5
• Total formula weight: 370481.07

Authors

Qiao, S.,Prabu, J.R.,Schulman, B.A. (deposition date: 2019-09-24, release date: 2019-11-20, Last modification date: 2022-07-20)

• Primary citation: Qiao, S.,Langlois, C.R.,Chrustowicz, J.,Sherpa, D.,Karayel, O.,Hansen, F.M.,Beier, V.,von Gronau, S.,Bollschweiler, D.,Schafer, T.,Alpi, A.F.,Mann, M.,Rajan Prabu, J.,Schulman, B.A.; Interconversion between Anticipatory and Active GID E3 Ubiquitin Ligase Conformations via Metabolically Driven Substrate Receptor Assembly; Mol.Cell, 77:1-14, 2020; PubMed: 31708416; DOI: 10.1016/j.molcel.2019.10.009

Experimental method

ELECTRON MICROSCOPY (3.2 Å)