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6SWY

Structure of active GID E3 ubiquitin ligase complex minus Gid2 and delta Gid9 RING domain

Functional Information from GO Data
ChainGOidnamespacecontents
10003674molecular_functionmolecular_function
10005515molecular_functionprotein binding
10005634cellular_componentnucleus
10005737cellular_componentcytoplasm
10006808biological_processregulation of nitrogen utilization
10007010biological_processcytoskeleton organization
10034657cellular_componentGID complex
10043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
10045721biological_processnegative regulation of gluconeogenesis
40003674molecular_functionmolecular_function
40005515molecular_functionprotein binding
40005773cellular_componentvacuole
40005829cellular_componentcytosol
40006623biological_processprotein targeting to vacuole
40007039biological_processprotein catabolic process in the vacuole
40015031biological_processprotein transport
40016020cellular_componentmembrane
40030659cellular_componentcytoplasmic vesicle membrane
40031410cellular_componentcytoplasmic vesicle
40034657cellular_componentGID complex
40043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
40045721biological_processnegative regulation of gluconeogenesis
40071596biological_processubiquitin-dependent protein catabolic process via the N-end rule pathway
50003674molecular_functionmolecular_function
50005515molecular_functionprotein binding
50005634cellular_componentnucleus
50005737cellular_componentcytoplasm
50005773cellular_componentvacuole
50007039biological_processprotein catabolic process in the vacuole
50030437biological_processascospore formation
50034657cellular_componentGID complex
50043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
50045721biological_processnegative regulation of gluconeogenesis
80003674molecular_functionmolecular_function
80005515molecular_functionprotein binding
80005634cellular_componentnucleus
80005737cellular_componentcytoplasm
80007089biological_processtraversing start control point of mitotic cell cycle
80034657cellular_componentGID complex
80043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
80045721biological_processnegative regulation of gluconeogenesis
90004842molecular_functionubiquitin-protein transferase activity
90043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsSITE: Interaction with the N-terminal Pro (Pro/N-degron) of proteins that are targeted for degradation => ECO:0000250|UniProtKB:Q8IVV7
ChainResidueDetails
4GLN133
4GLU294
4TYR316

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:18407956
ChainResidueDetails
4SER27
1SER248

site_idSWS_FT_FI3
Number of Residues2
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0007744|PubMed:22106047
ChainResidueDetails
4LYS20

site_idSWS_FT_FI4
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:19779198
ChainResidueDetails
1SER277

226707

PDB entries from 2024-10-30

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