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PDB: 3 results

5JBJ
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BU of 5jbj by Molmil
Crystal structure of chicken LGP2 with 5'p 12-mer dsRNA at 3.6 A resolution
Descriptor: LGP2, RNA (5'-R(P*GP*GP*UP*AP*GP*CP*GP*CP*UP*AP*CP*C)-3'), ZINC ION
Authors:Cusack, S, Uchikawa, E, Lethier, M.
Deposit date:2016-04-13
Release date:2016-06-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.58 Å)
Cite:Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5.
Mol.Cell, 62, 2016
6EUV
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BU of 6euv by Molmil
Structure of the midlink and cap-binding domains of influenza A polymerase PB2 subunit with a bound azaindole cap-binding inhibitor (VX-787)
Descriptor: (2S,3S)-3-[[5-fluoranyl-2-(5-fluoranyl-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid, NICKEL (II) ION, Polymerase basic protein 2
Authors:Cusack, S, Lethier, M.
Deposit date:2017-10-31
Release date:2017-12-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Capped RNA primer binding to influenza polymerase and implications for the mechanism of cap-binding inhibitors.
Nucleic Acids Res., 46, 2018
6FLN
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Crystal structure of the human TRIM25 coiled-coil and PRYSPRY domains
Descriptor: E3 ubiquitin/ISG15 ligase TRIM25
Authors:Cusack, S, Lethier, M.
Deposit date:2018-01-26
Release date:2018-05-23
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Molecular mechanism of influenza A NS1-mediated TRIM25 recognition and inhibition.
Nat Commun, 9, 2018

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