6E2H

Crystal structure of human Ash2L (SPRY domain and SDI motif) in complex with full length DPY-30

Summary for 6E2H

Entry DOI	10.2210/pdb6e2h/pdb
Descriptor	Set1/Ash2 histone methyltransferase complex subunit ASH2, Protein dpy-30 homolog (3 entities in total)
Functional Keywords	histone, epigenetics, set1, mll, lysine methylation, nucleosome, protein binding
Biological source	Homo sapiens (Human) More
Total number of polymer chains	3
Total formula weight	46611.62
Authors	Joshi, M.,Brunzelle, J.S.,Couture, J.F. (deposition date: 2018-07-11, release date: 2018-08-08, Last modification date: 2023-10-11)
Primary citation	Haddad, J.F.,Yang, Y.,Takahashi, Y.H.,Joshi, M.,Chaudhary, N.,Woodfin, A.R.,Benyoucef, A.,Yeung, S.,Brunzelle, J.S.,Skiniotis, G.,Brand, M.,Shilatifard, A.,Couture, J.F. Structural Analysis of the Ash2L/Dpy-30 Complex Reveals a Heterogeneity in H3K4 Methylation. Structure, 26:1594-, 2018 Cited by PubMed: 30270175 DOI: 10.1016/j.str.2018.08.004 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.236 Å)

Structure validation