6E2H
Crystal structure of human Ash2L (SPRY domain and SDI motif) in complex with full length DPY-30
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (D) | Set1/Ash2 histone methyltransferase complex subunit ASH2 | polymer | 214 | 23974.2 | 1 | UniProt (Q9UBL3) Pfam (PF00622) | Homo sapiens (Human) | ASH2-like protein |
| 2 | B, C (E, F) | Protein dpy-30 homolog | polymer | 100 | 11318.7 | 2 | UniProt (Q9C005) Pfam (PF05186) | Homo sapiens (Human) | Dpy-30-like protein,Dpy-30L |
| 3 | D, E, F (D, E, F) | water | water | 18.0 | 188 | Chemie (HOH) |
Sequence modifications
D: 286 - 491 (UniProt: Q9UBL3)
E, F: 1 - 99 (UniProt: Q9C005)
| PDB | External Database | Details |
|---|---|---|
| Ala 278 | - | expression tag |
| Thr 279 | - | expression tag |
| Tyr 280 | - | expression tag |
| Ala 281 | - | expression tag |
| Met 282 | - | expression tag |
| Gly 283 | - | expression tag |
| Ser 284 | - | expression tag |
| Met 285 | - | expression tag |
| - | Glu 497 | deletion |
| - | Thr 498 | deletion |
| - | Ala 499 | deletion |
| - | Lys 500 | deletion |
| - | Ser 501 | deletion |
| - | Leu 502 | deletion |
| - | Pro 503 | deletion |
| - | Asp 504 | deletion |
| - | Thr 505 | deletion |
| - | Tyr 506 | deletion |
| - | Lys 507 | deletion |
| - | Asp 508 | deletion |
| - | Lys 509 | deletion |
| - | Ala 510 | deletion |
| - | Leu 511 | deletion |
| - | Ile 512 | deletion |
| - | Lys 513 | deletion |
| - | Phe 514 | deletion |
| - | Lys 515 | deletion |
| - | Ser 516 | deletion |
| - | Tyr 517 | deletion |
| - | Leu 518 | deletion |
| - | Tyr 519 | deletion |
| - | Phe 520 | deletion |
| - | Glu 521 | deletion |
| - | Glu 522 | deletion |
| - | Lys 523 | deletion |
| - | Asp 524 | deletion |
| - | Phe 525 | deletion |
| - | Val 526 | deletion |
| - | Asp 527 | deletion |
| - | Lys 528 | deletion |
| - | Ala 529 | deletion |
| - | Glu 530 | deletion |
| - | Lys 531 | deletion |
| - | Ser 532 | deletion |
| - | Leu 533 | deletion |
| Ile 403 | Lys 534 | conflict |
| Ser 404 | Gln 535 | conflict |
| Gly 405 | Thr 536 | conflict |
| Arg 406 | Pro 537 | conflict |
| Gly 407 | His 538 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 46611.6 | |
| All* | Total formula weight | 46611.6 |
