5F6K

Crystal structure of the MLL3-Ash2L-RbBP5 complex

Summary for 5F6K

• Entry DOI: 10.2210/pdb5f6k/pdb
• Related: 5F59 5F5E 5F5L
• Descriptor: Set1/Ash2 histone methyltransferase complex subunit ASH2,Set1/Ash2 histone methyltransferase complex subunit ASH2, Histone-lysine N-methyltransferase 2C, Retinoblastoma-binding protein 5, ... (7 entities in total)
• Functional Keywords: histone methylation, histone methyltransferase, mll-family proteins, set domain, transferase-protein binding complex, transferase/protein binding
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus : Q9UBL3 Q8NEZ4 Q15291
• Total number of polymer chains: 7
• Total formula weight: 86552.41

Authors

Li, Y.,Lei, M.,Chen, Y. (deposition date: 2015-12-06, release date: 2016-02-24, Last modification date: 2023-11-08)

• Primary citation: Li, Y.,Han, J.,Zhang, Y.,Cao, F.,Liu, Z.,Li, S.,Wu, J.,Hu, C.,Wang, Y.,Shuai, J.,Chen, J.,Cao, L.,Li, D.,Shi, P.,Tian, C.,Zhang, J.,Dou, Y.,Li, G.,Chen, Y.,Lei, M.; Structural basis for activity regulation of MLL family methyltransferases.; Nature, 530:447-452, 2016; PubMed: 26886794; DOI: 10.1038/nature16952

Experimental method

X-RAY DIFFRACTION (2.411 Å)