5F5L

The structure of monooxygenase KstA11 in the biosynthetic pathway of kosinostatin

Summary for 5F5L

• Entry DOI: 10.2210/pdb5f5l/pdb
• Related: 5F5N
• Descriptor: Monooxygenase, GLYCEROL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ... (4 entities in total)
• Functional Keywords: monooxygenase, dearomatization, kosinostatin, oxidoreductase
• Biological source: Micromonospora sp. TP-A0468
• Total number of polymer chains: 1
• Total formula weight: 31638.95

Authors

Pan, L.,Gong, Y. (deposition date: 2015-12-04, release date: 2016-12-21, Last modification date: 2017-03-01)

• Primary citation: Zhang, Z.,Gong, Y.-K.,Zhou, Q.,Hu, Y.,Ma, H.-M.,Chen, Y.-S.,Igarashi, Y.,Pan, L.,Tang, G.-L.; Hydroxyl regioisomerization of anthracycline catalyzed by a four-enzyme cascade; Proc. Natl. Acad. Sci. U.S.A., 114:1554-1559, 2017; PubMed: 28137838; DOI: 10.1073/pnas.1610097114

Experimental method

X-RAY DIFFRACTION (1.68 Å)