8R1A
 
 | | Model of the membrane-bound GBP1 oligomer | | 分子名称: | ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, Guanylate binding protein 1, ... | | 著者 | Weismehl, M, Chu, X, Kutsch, M, Lauterjung, P, Herrmann, C, Kudryashev, M, Daumke, O. | | 登録日 | 2023-11-01 | | 公開日 | 2024-01-17 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (26.799999 Å) | | 主引用文献 | Structural insights into the activation mechanism of antimicrobial GBP1.
Embo J., 43, 2024
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8Q4L
 | | GBP1 bound by 14-3-3sigma | | 分子名称: | 14-3-3 protein sigma, Guanylate-binding protein 1 | | 著者 | Pfleiderer, M.M, Liu, X, Fisch, D, Anastasakou, E, Frickel, E.M, Galej, W.P. | | 登録日 | 2023-08-07 | | 公開日 | 2023-10-11 | | 最終更新日 | 2023-10-18 | | 実験手法 | ELECTRON MICROSCOPY (5.12 Å) | | 主引用文献 | PIM1 controls GBP1 activity to limit self-damage and to guard against pathogen infection.
Science, 382, 2023
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8CQB
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7OL3
 | | Human ATL1 N417ins (catalytic core) | | 分子名称: | Atlastin-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Kelly, C.M, Sondermann, H. | | 登録日 | 2021-05-19 | | 公開日 | 2021-07-21 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | A novel insertion mutation in atlastin 1 is associated with spastic quadriplegia, increased membrane tethering, and aberrant conformational switching.
J.Biol.Chem., 298, 2021
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7M1S
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7E5A
 | | interferon-inducible anti-viral protein R356A | | 分子名称: | ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, Guanylate-binding protein 5, ... | | 著者 | Cui, W, Wang, W, Chen, C, Slater, B, Xiong, Y, Ji, X.Y, Yang, H.T. | | 登録日 | 2021-02-18 | | 公開日 | 2021-05-05 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural basis for GTP-induced dimerization and antiviral function of guanylate-binding proteins.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7E59
 | | interferon-inducible anti-viral protein truncated | | 分子名称: | Guanylate-binding protein 5 | | 著者 | Cui, W, Wang, W, Chen, C, Slater, B, Xiong, Y, Ji, X.Y, Yang, H.T. | | 登録日 | 2021-02-18 | | 公開日 | 2021-05-05 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural basis for GTP-induced dimerization and antiviral function of guanylate-binding proteins.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7E58
 | | interferon-inducible anti-viral protein 2 | | 分子名称: | Guanylate-binding protein 2 | | 著者 | Cui, W, Wang, W, Chen, C, Slater, B, Xiong, Y, Ji, X.Y, Yang, H.T. | | 登録日 | 2021-02-18 | | 公開日 | 2021-05-05 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural basis for GTP-induced dimerization and antiviral function of guanylate-binding proteins.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7CKF
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6XJO
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6XJN
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6VKJ
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6LOJ
 | | The complex structure of IpaH9.8-LRR and hGBP1 | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Guanylate-binding protein 1, Invasion plasmid antigen | | 著者 | Ye, Y, Huang, H. | | 登録日 | 2020-01-06 | | 公開日 | 2020-12-23 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.72 Å) | | 主引用文献 | Substrate-binding destabilizes the hydrophobic cluster to relieve the autoinhibition of bacterial ubiquitin ligase IpaH9.8.
Commun Biol, 3, 2020
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6K2D
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6K1Z
 | | Crystal structure of farnesylated hGBP1 | | 分子名称: | FARNESYL, Guanylate-binding protein 1 | | 著者 | Du, S, Xiao, J.Y. | | 登録日 | 2019-05-13 | | 公開日 | 2019-06-12 | | 最終更新日 | 2019-12-25 | | 実験手法 | X-RAY DIFFRACTION (2.307 Å) | | 主引用文献 | Structural mechanism for guanylate-binding proteins (GBPs) targeting by the Shigella E3 ligase IpaH9.8.
Plos Pathog., 15, 2019
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6B9G
 | | human ATL1 GTPase domain bound to GDP | | 分子名称: | Atlastin-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | | 著者 | O'Donnell, J.P, Sondermann, H. | | 登録日 | 2017-10-10 | | 公開日 | 2017-12-06 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | A hereditary spastic paraplegia-associated atlastin variant exhibits defective allosteric coupling in the catalytic core.
J. Biol. Chem., 293, 2018
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6B9F
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6B9E
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6B9D
 | | Human ATL1 mutant - R77A bound to GDP | | 分子名称: | Atlastin-1, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | O'Donnell, J.P, Sondermann, H. | | 登録日 | 2017-10-10 | | 公開日 | 2017-12-06 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | A hereditary spastic paraplegia-associated atlastin variant exhibits defective allosteric coupling in the catalytic core.
J. Biol. Chem., 293, 2018
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5VGR
 | | Human Atlastin-3, GDP-bound | | 分子名称: | Atlastin-3, GUANOSINE-5'-DIPHOSPHATE | | 著者 | O'Donnell, J.P, Sondermann, H. | | 登録日 | 2017-04-11 | | 公開日 | 2017-05-17 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.096 Å) | | 主引用文献 | Timing and Reset Mechanism of GTP Hydrolysis-Driven Conformational Changes of Atlastin.
Structure, 25, 2017
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4IDQ
 | | human atlastin-1 1-446, N440T, GDPAlF4- | | 分子名称: | Atlastin-1, GUANOSINE-5'-DIPHOSPHATE, HEXAETHYLENE GLYCOL, ... | | 著者 | Byrnes, L.J, Singh, A, Szeto, K, Benvin, N.M, O'Donnell, J.P, Zipfel, W.R, Sondermann, H. | | 登録日 | 2012-12-12 | | 公開日 | 2013-01-09 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.295 Å) | | 主引用文献 | Structural basis for conformational switching and GTP loading of the large G protein atlastin.
Embo J., 32, 2013
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4IDP
 | | human atlastin-1 1-446, N440T, GppNHp | | 分子名称: | Atlastin-1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | | 著者 | Byrnes, L.J, Singh, A, Szeto, K, Benvin, N.M, O'Donnell, J.P, Zipfel, W.R, Sondermann, H. | | 登録日 | 2012-12-12 | | 公開日 | 2013-01-09 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.587 Å) | | 主引用文献 | Structural basis for conformational switching and GTP loading of the large G protein atlastin.
Embo J., 32, 2013
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4IDO
 | | human atlastin-1 1-446, C-his6, GDPAlF4- | | 分子名称: | Atlastin-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Byrnes, L.J, Singh, A, Szeto, K, Benvin, N.M, O'Donnell, J.P, Zipfel, W.R, Sondermann, H. | | 登録日 | 2012-12-12 | | 公開日 | 2013-01-09 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.091 Å) | | 主引用文献 | Structural basis for conformational switching and GTP loading of the large G protein atlastin.
Embo J., 32, 2013
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4IDN
 | | Human atlastin-1 1-446, C-his6, GppNHp | | 分子名称: | Atlastin-1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | | 著者 | Byrnes, L.J, Singh, A, Szeto, K, Benvin, N.M, O'Donnell, J.P, Zipfel, W.R, Sondermann, H. | | 登録日 | 2012-12-12 | | 公開日 | 2013-01-09 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.252 Å) | | 主引用文献 | Structural basis for conformational switching and GTP loading of the large G protein atlastin.
Embo J., 32, 2013
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3X1D
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