6B9E

Human ATL1 mutant - R77A / F151S bound to GDP

Summary for 6B9E

Entry DOI	10.2210/pdb6b9e/pdb
Descriptor	Atlastin-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (5 entities in total)
Functional Keywords	gtpase, dynamin related protein, hydrolysis-deficient, hydrolase
Biological source	Homo sapiens (Human)
Cellular location	Endoplasmic reticulum membrane ; Multi-pass membrane protein : Q8WXF7
Total number of polymer chains	2
Total formula weight	105915.57
Authors	O'Donnell, J.P.,Sondermann, H. (deposition date: 2017-10-10, release date: 2017-12-06, Last modification date: 2023-10-04)
Primary citation	O'Donnell, J.P.,Byrnes, L.J.,Cooley, R.B.,Sondermann, H. A hereditary spastic paraplegia-associated atlastin variant exhibits defective allosteric coupling in the catalytic core. J. Biol. Chem., 293:687-700, 2018 Cited by PubMed: 29180453 DOI: 10.1074/jbc.RA117.000380 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.99 Å)

Structure validation