8Q4L

GBP1 bound by 14-3-3sigma

Summary for 8Q4L

Entry DOI	10.2210/pdb8q4l/pdb
EMDB information	18149
Descriptor	Guanylate-binding protein 1, 14-3-3 protein sigma (2 entities in total)
Functional Keywords	protein complex, phosphorylation, immune system
Biological source	Homo sapiens (human) More
Total number of polymer chains	3
Total formula weight	118554.46
Authors	Pfleiderer, M.M.,Liu, X.,Fisch, D.,Anastasakou, E.,Frickel, E.M.,Galej, W.P. (deposition date: 2023-08-07, release date: 2023-10-11, Last modification date: 2023-10-18)
Primary citation	Fisch, D.,Pfleiderer, M.M.,Anastasakou, E.,Mackie, G.M.,Wendt, F.,Liu, X.,Clough, B.,Lara-Reyna, S.,Encheva, V.,Snijders, A.P.,Bando, H.,Yamamoto, M.,Beggs, A.D.,Mercer, J.,Shenoy, A.R.,Wollscheid, B.,Maslowski, K.M.,Galej, W.P.,Frickel, E.M. PIM1 controls GBP1 activity to limit self-damage and to guard against pathogen infection. Science, 382:eadg2253-eadg2253, 2023 Cited by PubMed: 37797010 DOI: 10.1126/science.adg2253 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (5.12 Å)

Structure validation