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8CQB

Cryo-EM structure of the human GBP1 dimer bound to GDP-AlF3

Summary for 8CQB
Entry DOI10.2210/pdb8cqb/pdb
EMDB information16794
DescriptorGuanylate-binding protein 1, GUANOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, ... (4 entities in total)
Functional Keywordscell-autonomous immunity, intracellular pathogens, gtpase, immune system
Biological sourceHomo sapiens (human)
Total number of polymer chains2
Total formula weight137146.20
Authors
Kuhm, T.I.,Jakobi, A.J. (deposition date: 2023-03-04, release date: 2024-03-13)
Primary citationKuhm, T.I.,de Agrela Pinto, C.,Taisne, C.,Huber, S.,Giannopolou, N.,Pardon, E.,Steyaert, J.,Jakobi, A.J.
Cryo-EM structure of the human GBP1 dimer bound to GDP-AlF3
To Be Published,
Experimental method
ELECTRON MICROSCOPY (3.7 Å)
Structure validation

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