7E5A

interferon-inducible anti-viral protein R356A

Summary for 7E5A

• Entry DOI: 10.2210/pdb7e5a/pdb
• Descriptor: Guanylate-binding protein 5, GUANOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, ... (5 entities in total)
• Functional Keywords: interferon-induced, gtpase, anti-hiv, hydrolase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 110956.01

Authors

Cui, W.,Wang, W.,Chen, C.,Slater, B.,Xiong, Y.,Ji, X.Y.,Yang, H.T. (deposition date: 2021-02-18, release date: 2021-05-05, Last modification date: 2023-11-29)

• Primary citation: Cui, W.,Braun, E.,Wang, W.,Tang, J.,Zheng, Y.,Slater, B.,Li, N.,Chen, C.,Liu, Q.,Wang, B.,Li, X.,Duan, Y.,Xiao, Y.,Ti, R.,Hotter, D.,Ji, X.,Zhang, L.,Cui, J.,Xiong, Y.,Sauter, D.,Wang, Z.,Kirchhoff, F.,Yang, H.; Structural basis for GTP-induced dimerization and antiviral function of guanylate-binding proteins.; Proc.Natl.Acad.Sci.USA, 118:-, 2021; PubMed: 33876762; DOI: 10.1073/pnas.2022269118

Experimental method

X-RAY DIFFRACTION (2.5 Å)