6B9D
Human ATL1 mutant - R77A bound to GDP
Summary for 6B9D
Entry DOI | 10.2210/pdb6b9d/pdb |
Descriptor | Atlastin-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | gtpase, dynamin related protein, hydrolysis-deficient, hydrolase |
Biological source | Homo sapiens (Human) |
Cellular location | Endoplasmic reticulum membrane ; Multi-pass membrane protein : Q8WXF7 |
Total number of polymer chains | 2 |
Total formula weight | 106492.26 |
Authors | O'Donnell, J.P.,Sondermann, H. (deposition date: 2017-10-10, release date: 2017-12-06, Last modification date: 2023-10-04) |
Primary citation | O'Donnell, J.P.,Byrnes, L.J.,Cooley, R.B.,Sondermann, H. A hereditary spastic paraplegia-associated atlastin variant exhibits defective allosteric coupling in the catalytic core. J. Biol. Chem., 293:687-700, 2018 Cited by PubMed: 29180453DOI: 10.1074/jbc.RA117.000380 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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