6B9D

Human ATL1 mutant - R77A bound to GDP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003924	molecular_function	GTPase activity
A	0005525	molecular_function	GTP binding
B	0003924	molecular_function	GTPase activity
B	0005525	molecular_function	GTP binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	17
Details	binding site for residue GDP A 501

Chain	Residue
A	ALA77
A	PRO272
A	VAL276
A	ASN279
A	PRO280
A	MG502
A	HOH637
A	HOH673
A	HOH700
A	LYS78
A	GLY79
A	LYS80
A	SER81
A	PHE82
A	GLN148
A	ARG217
A	ASP218

---

site_id	AC2
Number of Residues	5
Details	binding site for residue MG A 502

Chain	Residue
A	LYS80
A	SER81
A	ASP146
A	GLN148
A	GDP501

---

site_id	AC3
Number of Residues	9
Details	binding site for residue GOL A 503

Chain	Residue
A	MET91
A	TYR92
A	ASN93
A	GLN94
A	HOH605
B	GLN180
B	ASN181
B	SER220
B	PHE221

---

site_id	AC4
Number of Residues	8
Details	binding site for residue GOL A 504

Chain	Residue
A	ALA200
A	THR204
A	LEU206
A	LYS207
A	PRO208
A	ASN316
A	MET408
A	HOH668

---

site_id	AC5
Number of Residues	7
Details	binding site for residue GOL A 505

Chain	Residue
A	TYR92
A	ASN93
A	HOH626
B	ASN181
B	PHE221
B	PHE225
B	ARG239

---

site_id	AC6
Number of Residues	16
Details	binding site for residue GDP B 501

Chain	Residue
B	ALA77
B	LYS78
B	GLY79
B	LYS80
B	SER81
B	PHE82
B	GLN148
B	ARG217
B	ASP218
B	PRO272
B	VAL276
B	ALA277
B	ASN279
B	MG502
B	HOH613
B	HOH642

---

site_id	AC7
Number of Residues	4
Details	binding site for residue MG B 502

Chain	Residue
B	LYS80
B	ASP146
B	GLN148
B	GDP501

---

site_id	AC8
Number of Residues	4
Details	binding site for residue GOL B 503

Chain	Residue
B	ASN54
B	ARG55
B	LEU58
B	SER59

---

site_id	AC9
Number of Residues	7
Details	binding site for residue GOL B 504

Chain	Residue
A	GLN180
A	ASN181
A	SER220
A	PHE221
B	GLN94
B	GLU95
B	HOH621

---

site_id	AD1
Number of Residues	8
Details	binding site for residue GOL B 505

Chain	Residue
B	GLU327
B	LYS330
B	ALA331
B	LYS334
B	GLU353
B	LEU357
B	HOH652
B	HOH653

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	16
Details	Binding site: {"evidences":[{"source":"PubMed","id":"23334294","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"4IDN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4IDP","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"21220294","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21368113","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3Q5D","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3QNU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3QOF","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PDB","id":"6XJN","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"21220294","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21368113","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34546351","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3Q5D","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3Q5E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3QNU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3QOF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6XJN","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q6DD88","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	27
Details	Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---