8R1A

Model of the membrane-bound GBP1 oligomer

Summary for 8R1A

Entry DOI	10.2210/pdb8r1a/pdb
EMDB information	18806
Descriptor	Guanylate binding protein 1, ALUMINUM FLUORIDE, MAGNESIUM ION, ... (4 entities in total)
Functional Keywords	oligomer, gtpase, interferon-induced, antimicrobial protein
Biological source	Homo sapiens (human)
Total number of polymer chains	6
Total formula weight	418916.48
Authors	Weismehl, M.,Chu, X.,Kutsch, M.,Lauterjung, P.,Herrmann, C.,Kudryashev, M.,Daumke, O. (deposition date: 2023-11-01, release date: 2024-01-17, Last modification date: 2024-02-28)
Primary citation	Weismehl, M.,Chu, X.,Kutsch, M.,Lauterjung, P.,Herrmann, C.,Kudryashev, M.,Daumke, O. Structural insights into the activation mechanism of antimicrobial GBP1. Embo J., 43:615-636, 2024 Cited by PubMed: 38267655 DOI: 10.1038/s44318-023-00023-y PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (26.8 Å)

Structure validation