6SB3
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5J69
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5OUQ
| Structure of TgPLP1 MACPF domain | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Perforin-like protein 1 | 著者 | Ni, T, Gilbert, R.J.C. | 登録日 | 2017-08-24 | 公開日 | 2018-04-11 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (5.11 Å) | 主引用文献 | Structures of monomeric and oligomeric forms of theToxoplasma gondiiperforin-like protein 1. Sci Adv, 4, 2018
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5OWN
| Structure of TgPLP1 MACPF domain | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Perforin-like protein 1 | 著者 | Ni, T, Gilbert, R.J.C. | 登録日 | 2017-09-01 | 公開日 | 2018-04-11 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | 主引用文献 | Structures of monomeric and oligomeric forms of theToxoplasma gondiiperforin-like protein 1. Sci Adv, 4, 2018
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5OUP
| Structure of TgPLP1 MACPF domain | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Perforin-like protein 1 | 著者 | Ni, T, Gilbert, R.J.C. | 登録日 | 2017-08-24 | 公開日 | 2018-04-11 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Structures of monomeric and oligomeric forms of theToxoplasma gondiiperforin-like protein 1. Sci Adv, 4, 2018
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2QQH
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6SB5
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6U2J
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6U2W
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6U23
| EM structure of MPEG-1(w.t.) soluble pre-pore | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Macrophage-expressed gene 1 protein | 著者 | Pang, S.S, Bayly-Jones, C. | 登録日 | 2019-08-19 | 公開日 | 2019-09-25 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.49 Å) | 主引用文献 | The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1. Nat Commun, 10, 2019
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6U2L
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6U2K
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8A1S
| Structure of murine perforin-2 (Mpeg1) pore in twisted form | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Macrophage-expressed gene 1 protein | 著者 | Yu, X, Ni, T, Zhang, P, Gilbert, R. | 登録日 | 2022-06-02 | 公開日 | 2022-07-20 | 最終更新日 | 2023-10-18 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Cryo-EM structures of perforin-2 in isolation and assembled on a membrane suggest a mechanism for pore formation. Embo J., 41, 2022
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8A1D
| Structure of murine perforin-2 (Mpeg1) pore in ring form | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CYCLOHEXYL-HEXYL-BETA-D-MALTOSIDE, Macrophage-expressed gene 1 protein | 著者 | Yu, X, Ni, T, Zhang, P, Gilbert, R. | 登録日 | 2022-06-01 | 公開日 | 2022-07-20 | 最終更新日 | 2022-12-14 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Cryo-EM structures of perforin-2 in isolation and assembled on a membrane suggest a mechanism for pore formation. Embo J., 41, 2022
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6FBM
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5J68
| Structure of Astrotactin-2, a conserved vertebrate-specific and perforin-like membrane protein involved in neuronal development | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Astrotactin-2, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, ... | 著者 | Ni, T, Harlos, K, Gilbert, R.J.C. | 登録日 | 2016-04-04 | 公開日 | 2016-05-25 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (5.221 Å) | 主引用文献 | Structure of astrotactin-2: a conserved vertebrate-specific and perforin-like membrane protein involved in neuronal development. Open Biology, 6, 2016
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5J67
| Structure of Astrotactin-2, a conserved vertebrate-specific and perforin-like membrane protein involved in neuronal development | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Astrotactin-2, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, ... | 著者 | Ni, T, Harlos, K, Gilbert, R.J.C. | 登録日 | 2016-04-04 | 公開日 | 2016-05-25 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.16 Å) | 主引用文献 | Structure of astrotactin-2: a conserved vertebrate-specific and perforin-like membrane protein involved in neuronal development. Open Biology, 6, 2016
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2QP2
| Structure of a MACPF/perforin-like protein | 分子名称: | CALCIUM ION, Unknown protein | 著者 | Rosado, C.J, Buckle, A.M, Law, R.H.P, Butcher, R.E, Kan, W.T, Bird, C.H, Ung, K, Browne, K.A, Baran, K, Bashtannyk-Puhalovich, T.A, Faux, N.G, Wong, W, Porter, C.J, Pike, R.N, Ellisdon, A.M, Pearce, M.C, Bottomley, S.P, Emsley, J, Smith, A.I, Rossjohn, J, Hartland, E.L, Voskoboinik, I, Trapani, J.A, Bird, P.I, Dunstone, M.A, Whisstock, J.C. | 登録日 | 2007-07-22 | 公開日 | 2007-09-04 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A common fold mediates vertebrate defense and bacterial attack Science, 317, 2007
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8B6U
| Mpf2Ba1 monomer | 分子名称: | MAGNESIUM ION, Mpf2Ba1 | 著者 | Marini, G, Poland, B, Leininger, C, Lukoyanova, N, Spielbauer, D, Barry, J, Altier, D, Lum, A, Scolaro, E, Perez-Ortega, C, Yalpani, N, Sandahl, G, Mabry, T, Klever, J, Nowatzki, T, Zhao, J.Z, Sethi, A, Kassa, A, Crane, V, Lu, A, Nelson, M.E, Eswar, N, Topf, M, Saibil, H.R. | 登録日 | 2022-09-27 | 公開日 | 2023-05-31 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.134 Å) | 主引用文献 | Structural journey of an insecticidal protein against western corn rootworm. Nat Commun, 14, 2023
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8B6W
| Mpf2Ba1 pore | 分子名称: | MAGNESIUM ION, Mpf2Ba1 | 著者 | Marini, G, Poland, B, Leininger, C, Lukoyanova, N, Spielbauer, D, Barry, J, Altier, D, Lum, A, Scolaro, E, Perez Ortega, C, Yalpani, N, Sandahl, G, Mabry, T, Klever, J, Nowatzki, T, Zhao, J.Z, Sethi, A, Kassa, A, Crane, V, Lu, A, Nelson, M.E, Eswar, N, Topf, M, Saibil, H.R. | 登録日 | 2022-09-27 | 公開日 | 2023-05-31 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Structural journey of an insecticidal protein against western corn rootworm. Nat Commun, 14, 2023
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8B6V
| Mp2Ba1 pre-pore | 分子名称: | MAGNESIUM ION, Mpf2Ba1 | 著者 | Marini, G, Poland, B, Leininger, C, Lukoyanova, N, Spielbauer, D, Barry, J, Altier, D, Lum, A, Scolaro, E, Perez Ortega, C, Yalpani, N, Sandahl, G, Mabry, T, Klever, J, Nowatzki, T, Zhao, J.Z, Sethi, A, Kassa, A, Crane, V, Lu, A, Nelson, M.E, Eswar, N, Topf, M, Saibil, H.R. | 登録日 | 2022-09-27 | 公開日 | 2023-05-31 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural journey of an insecticidal protein against western corn rootworm. Nat Commun, 14, 2023
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5FMW
| The poly-C9 component of the Complement Membrane Attack Complex | 分子名称: | POLYC9 | 著者 | Dudkina, N.V, Spicer, B.A, Reboul, C.F, Conroy, P.J, Lukoyanova, N, Elmlund, H, Law, R.H.P, Ekkel, S.M, Kondos, S.C, Goode, R.J.A, Ramm, G, Whisstock, J.C, Saibil, H.R, Dunstone, M.A. | 登録日 | 2015-11-10 | 公開日 | 2016-02-17 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (6.7 Å) | 主引用文献 | Structure of the Poly-C9 Component of the Complement Membrane Attack Complex Nat.Commun., 7, 2016
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4E0S
| Crystal Structure of C5b-6 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Complement C5, ... | 著者 | Aleshin, A.E, Stec, B, DiScipio, R, Liddington, R.C. | 登録日 | 2012-03-05 | 公開日 | 2012-04-18 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (4.21 Å) | 主引用文献 | Crystal structure of c5b-6 suggests structural basis for priming assembly of the membrane attack complex. J.Biol.Chem., 287, 2012
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8DE6
| Oligomeric C9 in complex with aE11 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Complement component C9, ... | 著者 | Bayly-Jones, C. | 登録日 | 2022-06-20 | 公開日 | 2023-01-25 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | The neoepitope of the complement C5b-9 Membrane Attack Complex is formed by proximity of adjacent ancillary regions of C9. Commun Biol, 6, 2023
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4A5W
| Crystal structure of C5b6 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, COMPLEMENT C5, ... | 著者 | Hadders, M.A, Bubeck, D, Forneris, F, Pangburn, M, Llorca, O, Lea, S.M, Gros, P. | 登録日 | 2011-10-28 | 公開日 | 2012-03-14 | 最終更新日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Assembly and Regulation of the Membrane Attack Complex Based on Structures of C5B6 and Sc5B9. Cell Rep., 1, 2012
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