8A1S
Structure of murine perforin-2 (Mpeg1) pore in twisted form
This is a non-PDB format compatible entry.
Summary for 8A1S
Entry DOI | 10.2210/pdb8a1s/pdb |
EMDB information | 10134 10135 15072 15086 |
Descriptor | Macrophage-expressed gene 1 protein, 2-acetamido-2-deoxy-beta-D-glucopyranose (2 entities in total) |
Functional Keywords | pore forming protein, macpf, beta-barrel, immunity, immune system |
Biological source | Mus musculus (house mouse) |
Total number of polymer chains | 16 |
Total formula weight | 1145296.32 |
Authors | Yu, X.,Ni, T.,Zhang, P.,Gilbert, R. (deposition date: 2022-06-02, release date: 2022-07-20, Last modification date: 2023-10-18) |
Primary citation | Yu, X.,Ni, T.,Munson, G.,Zhang, P.,Gilbert, R.J.C. Cryo-EM structures of perforin-2 in isolation and assembled on a membrane suggest a mechanism for pore formation. Embo J., 41:e111857-e111857, 2022 Cited by PubMed: 36245269DOI: 10.15252/embj.2022111857 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4 Å) |
Structure validation
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