8DE6

Oligomeric C9 in complex with aE11 Fab

This is a non-PDB format compatible entry.

Summary for 8DE6

• Entry DOI: 10.2210/pdb8de6/pdb
• EMDB information: 27385
• Descriptor: aE11 Fab VH, aE11 Fab VL, Complement component C9, ... (6 entities in total)
• Functional Keywords: membrane attack complex, complement component 9, polyc9, ae11, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 7
• Total formula weight: 251669.00

Authors

Bayly-Jones, C. (deposition date: 2022-06-20, release date: 2023-01-25)

• Primary citation: Bayly-Jones, C.,Ho, B.H.T.,Lau, C.,Leung, E.W.W.,D'Andrea, L.,Lupton, C.J.,Ekkel, S.M.,Venugopal, H.,Whisstock, J.C.,Mollnes, T.E.,Spicer, B.A.,Dunstone, M.A.; The neoepitope of the complement C5b-9 Membrane Attack Complex is formed by proximity of adjacent ancillary regions of C9.; Commun Biol, 6:42-42, 2023; PubMed: 36639734; DOI: 10.1038/s42003-023-04431-y

Experimental method

ELECTRON MICROSCOPY (3.2 Å)