8DE6

Oligomeric C9 in complex with aE11 Fab

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005579	cellular_component	membrane attack complex
A	0006955	biological_process	immune response
C	0005579	cellular_component	membrane attack complex
C	0006955	biological_process	immune response
G	0005579	cellular_component	membrane attack complex
G	0006955	biological_process	immune response

Functional Information from PROSITE/UniProt

site_id	PS00022
Number of Residues	12
Details	EGF_1 EGF-like domain signature 1. CaCpfKfeGIaC

Chain	Residue	Details
A	CYS462-CYS473

---

site_id	PS00279
Number of Residues	12
Details	MACPF_1 Membrane attack complex/perforin (MACPF) domain signature. YfafletYGTHY

Chain	Residue	Details
A	TYR283-TYR294

---

site_id	PS01186
Number of Residues	14
Details	EGF_2 EGF-like domain signature 2. ClCacPFkfegia..C

Chain	Residue	Details
A	CYS460-CYS473

---

site_id	PS01209
Number of Residues	23
Details	LDLRA_1 LDL-receptor class A (LDLRA) domain signature. CIkmrlr.CNgdnDCgdfsDEDd....C

Chain	Residue	Details
A	CYS91-CYS113

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	159
Details	Domain: {"description":"TSP type-1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00210","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	111
Details	Domain: {"description":"LDL-receptor class A","evidences":[{"source":"PROSITE-ProRule","id":"PRU00124","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	90
Details	Domain: {"description":"EGF-like"}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	3
Details	Glycosylation: {"description":"C-linked (Man) tryptophan","evidences":[{"source":"PubMed","id":"10551839","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	3
Details	Glycosylation: {"description":"C-linked (Man) tryptophan; partial","evidences":[{"source":"PubMed","id":"10551839","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	3
Details	Glycosylation: {"description":"N-linked (GlcNAc...) (complex) asparagine","evidences":[{"source":"PubMed","id":"14760718","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16263699","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16335952","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19139490","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30552328","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"4055801","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---