8A1D

Structure of murine perforin-2 (Mpeg1) pore in ring form

This is a non-PDB format compatible entry.

Summary for 8A1D

• Entry DOI: 10.2210/pdb8a1d/pdb
• EMDB information: 10134 10135 15072
• Descriptor: Macrophage-expressed gene 1 protein, 2-acetamido-2-deoxy-beta-D-glucopyranose, CYCLOHEXYL-HEXYL-BETA-D-MALTOSIDE (3 entities in total)
• Functional Keywords: pore forming protein, macpf, beta-barrel, immunity, immune system
• Biological source: Mus musculus (house mouse)
• Total number of polymer chains: 16
• Total formula weight: 1153433.92

Authors

Yu, X.,Ni, T.,Zhang, P.,Gilbert, R. (deposition date: 2022-06-01, release date: 2022-07-20, Last modification date: 2022-12-14)

• Primary citation: Yu, X.,Ni, T.,Munson, G.,Zhang, P.,Gilbert, R.J.C.; Cryo-EM structures of perforin-2 in isolation and assembled on a membrane suggest a mechanism for pore formation.; Embo J., 41:e111857-e111857, 2022; PubMed: 36245269; DOI: 10.15252/embj.2022111857

Experimental method

ELECTRON MICROSCOPY (3 Å)