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Showing 1 - 50 of 59 items for (author: kleiger & g)

EMDB-46644: 
Cryo-EM structure of a trapped ARIH1-diUB-CRL2-KLHDC10 complex - consensus map
Method: single particle / : Chittori S, Scott DC, Schulman BA

EMDB-46645: 
Focused map of Cryo-EM structure of Ubiquitin C-degron bound to KLHDC10-EloB/C
Method: single particle / : Chittori S, Scott DC, Schulman BA

PDB-9d8p: 
Focused map of Cryo-EM structure of Ubiquitin C-degron bound to KLHDC10-EloB/C
Method: single particle / : Chittori S, Scott DC, Schulman BA

EMDB-19856: 
Focused map 1- K48-linked ubiquitin chain formation with a cullin-RING E3 ligase & Cdc34: NEDD8-CUL2-RBX1-ELOB/C-FEM1C with trapped UBE2R2~donor UB~acceptor UB-SIL1 peptide
Method: single particle / : Liwocha J, Prabu JR, Kleiger G, Schulman BA

EMDB-19857: 
Focused map 2 - K48-linked ubiquitin chain formation with a cullin-RING E3 ligase & Cdc34: NEDD8-CUL2-RBX1-ELOB/C-FEM1C with trapped UBE2R2~donor UB~acceptor UB-SIL1 peptide
Method: single particle / : Liwocha J, Prabu JR, Kleiger G, Schulman BA

EMDB-19858: 
Focused map 3 - K48-linked ubiquitin chain formation with a cullin-RING E3 ligase & Cdc34: NEDD8-CUL2-RBX1-ELOB/C-FEM1C with trapped UBE2R2~donor UB~acceptor UB-SIL1 peptide
Method: single particle / : Liwocha J, Prabu JR, Kleiger G, Schulman BA

EMDB-19859: 
Focused map 4 - K48-linked ubiquitin chain formation with a cullin-RING E3 ligase & Cdc34: NEDD8-CUL2-RBX1-ELOB/C-FEM1C with trapped UBE2R2~donor UB~acceptor UB-SIL1 peptide
Method: single particle / : Liwocha J, Prabu JR, Kleiger G, Schulman BA

EMDB-19860: 
Focused map 5 - K48-linked ubiquitin chain formation with a cullin-RING E3 ligase & Cdc34: NEDD8-CUL2-RBX1-ELOB/C-FEM1C with trapped UBE2R2~donor UB~acceptor UB-SIL1 peptide
Method: single particle / : Liwocha J, Prabu JR, Kleiger G, Schulman BA

EMDB-18207: 
Ubiquitin ligation to substrate by a cullin-RING E3 ligase & Cdc34: NEDD8-CUL2-RBX1-ELOB/C-FEM1C with trapped UBE2R2~donor UB-Sil1 peptide, Glacios map
Method: single particle / : Liwocha J, Prabu JR, Kleiger G, Schulman BA

EMDB-18230: 
Ubiquitin ligation to substrate by a cullin-RING E3 ligase & Cdc34: NEDD8-CUL2-RBX1-ELOB/C-FEM1C with trapped UBE2R2~donor UB-Sil1 peptide
Method: single particle / : Liwocha J, Prabu JR, Kleiger G, Schulman BA

EMDB-18915: 
Ubiquitin ligation to neosubstrate by a cullin-RING E3 ligase & Cdc34: NEDD8-CUL2-RBX1-ELOB/C-VHL-MZ1 with trapped UBE2R2~donor UB-BRD4 BD2
Method: single particle / : Liwocha J, Prabu JR, Kleiger G, Schulman BA

PDB-8q7r: 
Ubiquitin ligation to substrate by a cullin-RING E3 ligase & Cdc34: NEDD8-CUL2-RBX1-ELOB/C-FEM1C with trapped UBE2R2~donor UB-Sil1 peptide
Method: single particle / : Liwocha J, Prabu JR, Kleiger G, Schulman BA

PDB-8r5h: 
Ubiquitin ligation to neosubstrate by a cullin-RING E3 ligase & Cdc34: NEDD8-CUL2-RBX1-ELOB/C-VHL-MZ1 with trapped UBE2R2~donor UB-BRD4 BD2
Method: single particle / : Liwocha J, Prabu JR, Kleiger G, Schulman BA

EMDB-17798: 
CUL2-RBX1-ELOB/C-FEM1C-SIL1 conformation 1
Method: single particle / : Liwocha J, Prabu JR, Kleiger G, Schulman BA

EMDB-17799: 
CUL2-RBX1-ELOB/C-FEM1C-SIL1 conformation 2
Method: single particle / : Liwocha J, Prabu JR, Kleiger G, Schulman BA

EMDB-17800: 
NEDD8-CUL2-RBX1-ELOB/C-FEM1C-SIL1 conformation 1
Method: single particle / : Liwocha J, Prabu JR, Kleiger G, Schulman BA

EMDB-17801: 
NEDD8-CUL2-RBX1-ELOB/C-FEM1C-SIL1 conformation 2
Method: single particle / : Liwocha J, Prabu JR, Kleiger G, Schulman BA

EMDB-17802: 
K48-linked ubiquitin chain formation with a cullin-RING E3 ligase and Cdc34: NEDD8-CUL1-RBX1-SKP1-FBXW7 with trapped UBE2R2-donor UB-acceptor UB-cyclin E peptide
Method: single particle / : Liwocha J, Prabu JR, Kleiger G, Schulman BA

EMDB-17803: 
Consensus map - K48-linked ubiquitin chain formation with a cullin-RING E3 ligase and Cdc34: NEDD8-CUL2-RBX1-ELOB/C-FEM1C with trapped UBE2R2-donor UB-acceptor UB-SIL1 peptide
Method: single particle / : Liwocha J, Prabu JR, Kleiger G, Schulman BA

EMDB-17822: 
K48-linked ubiquitin chain formation with a cullin-RING E3 ligase and Cdc34: NEDD8-CUL2-RBX1-ELOB/C-FEM1C with trapped UBE2R2-donor UB-acceptor UB-SIL1 peptide
Method: single particle / : Liwocha J, Prabu JR, Kleiger G, Schulman BA

EMDB-18767: 
K48-linked ubiquitin chain formation with a cullin-RING E3 ligase & Cdc34: NEDD8-CUL2-RBX1-ELOB/C-VHL-MZ1 with trapped UBE2R2~donor UB~acceptor UB-BRD4
Method: single particle / : Liwocha J, Prabu JR, Kleiger G, Schulman BA

PDB-8pql: 
K48-linked ubiquitin chain formation with a cullin-RING E3 ligase and Cdc34: NEDD8-CUL2-RBX1-ELOB/C-FEM1C with trapped UBE2R2-donor UB-acceptor UB-SIL1 peptide
Method: single particle / : Liwocha J, Prabu JR, Kleiger G, Schulman BA

EMDB-17705: 
Structure of Chelator-GIDSR4 - Fbp1 - phospho-Ubc8~ubiquitin - class I
Method: single particle / : Chrustowicz J, Sherpa D, Schulman BA

EMDB-17706: 
Structure of Chelator-GIDSR4 - Fbp1 - phospho-Ubc8~ubiquitin - class II
Method: single particle / : Chrustowicz J, Sherpa D, Schulman BA

EMDB-17707: 
Chelator-GIDSR4 - Fbp1 - phospho-Ubc8~ubiquitin - class III
Method: single particle / : Chrustowicz J, Sherpa D, Schulman BA

EMDB-17709: 
Structure of Chelator-GIDSR4 - Fbp1 - phospho-Ubc8~ubiquitin - class V
Method: single particle / : Chrustowicz J, Sherpa D, Schulman BA

EMDB-17710: 
Structure of Chelator-GIDSR4 - Fbp1 - phospho-Ubc8~ubiquitin - class IV
Method: single particle / : Chrustowicz J, Sherpa D, Schulman BA

EMDB-17713: 
Catalytic module of human CTLH E3 ligase bound to multiphosphorylated UBE2H~ubiquitin
Method: single particle / : Chrustowicz J, Sherpa D, Prabu RJ, Schulman BA

EMDB-17715: 
SRS and Cat modules of human CTLHSR4 bound to multiphosphorylated UBE2H~ubiquitin
Method: single particle / : Chrustowicz J, Sherpa D, Schulman BA

EMDB-17716: 
Structure of CTLHSR4 - phospho-UBE2H~ubiquitin bound to engineered VH
Method: single particle / : Chrustowicz J, Sherpa D, Schulman BA

EMDB-17717: 
SRS and Cat modules of yeast Chelator-GIDSR4 bound to multiphosphorylated Ubc8~ubiquitin
Method: single particle / : Chrustowicz J, Sherpa D, Schulman BA

EMDB-17764: 
Catalytic module of yeast GID E3 ligase bound to multiphosphorylated Ubc8~ubiquitin
Method: single particle / : Chrustowicz J, Sherpa D, Prabu RJ, Schulman BA

PDB-8pjn: 
Catalytic module of human CTLH E3 ligase bound to multiphosphorylated UBE2H~ubiquitin
Method: single particle / : Chrustowicz J, Sherpa D, Prabu RJ, Schulman BA

PDB-8pmq: 
Catalytic module of yeast GID E3 ligase bound to multiphosphorylated Ubc8~ubiquitin
Method: single particle / : Chrustowicz J, Sherpa D, Prabu RJ, Schulman BA

EMDB-16370: 
Structure of CUL2-KLHDC2 E3 ligase autoinhibited by C-degron mimicry
Method: single particle / : Scott DC, King M, Baek K, Schulman BA

EMDB-12040: 
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: CUL1-RBX1-SKP1-SKP2-CKSHS1-p27~Ub~ARIH1. Transition State 2
Method: single particle / : Horn-Ghetko D, Prabu JR, Schulman BA

PDB-7b5m: 
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: CUL1-RBX1-SKP1-SKP2-CKSHS1-p27~Ub~ARIH1. Transition State 2
Method: single particle / : Horn-Ghetko D, Prabu JR, Schulman BA

EMDB-12004: 
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 ligase superassembly. NEDD8-CUL1-RBX1-SKP1-FBXW7-Cyclin E-ARIH1-UBE2L3~Ub. Pre-Transition State 1
Method: single particle / : Horn-Ghetko D, Prabu JR, Schulman BA

EMDB-12005: 
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: NEDD8-CUL1-RBX1-SKP1-FBXW7-Cyclin E-ARIH1~Ub. post-Transition State 1
Method: single particle / : Horn-Ghetko D, Prabu JR, Schulman BA

EMDB-12006: 
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: CUL1-RBX1-SKP1-FBXW7-Cyclin E~Ub~ARIH1. Transition State 2
Method: single particle / : Horn-Ghetko D, Prabu JR, Schulman BA

EMDB-12036: 
Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly
Method: single particle / : Horn-Ghetko D, Prabu JR, Schulman BA

EMDB-12037: 
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: NEDD8-CUL1-RBX1-SKP1-SKP2-CKSHS1-Cyclin A-CDK2-p27-UBE2L3~Ub~ARIH1. Transition State 1
Method: single particle / : Horn-Ghetko D, Prabu JR, Schulman BA

EMDB-12038: 
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: NEDD8-CUL1-RBX1-SKP1-SKP2-CKSHS1-Cyclin A-CDK2-p27-UBE2L3~Ub~ARIH1. Transition State 1
Method: single particle / : Horn-Ghetko D, Prabu JR, Schulman BA

EMDB-12039: 
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: NEDD8-CUL1-RBX1-SKP1-FBXW7-Cyclin E~Ub~ARIH1. Transition State 2
Method: single particle / : Horn-Ghetko D, Prabu JR, Schulman BA

EMDB-12041: 
Focused map-catalytic side. Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: NEDD8-CUL1-RBX1-UBE2L3~Ub~ARIH1.
Method: single particle / : Horn-Ghetko D, Prabu JR, Schulman BA

EMDB-12048: 
Focused map- CyclinA-CDK2-class. Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: CUL1-RBX1-SKP1-SKP2-CKSHS1-Cyclin A-CDK2-p27. Transition State 1
Method: single particle / : Horn-Ghetko D, Prabu JR, Schulman BA

EMDB-12050: 
Focused map- Cullin scaffold. Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: CUL1-RBX1-ARIH1 Ariadne. Transition State 1
Method: single particle / : Horn-Ghetko D, Prabu JR, Schulman BA

PDB-7b5l: 
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: NEDD8-CUL1-RBX1-SKP1-SKP2-CKSHS1-Cyclin A-CDK2-p27-UBE2L3~Ub~ARIH1. Transition State 1
Method: single particle / : Horn-Ghetko D, Prabu JR, Schulman BA

PDB-7b5n: 
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: NEDD8-CUL1-RBX1-UBE2L3~Ub~ARIH1.
Method: single particle / : Horn-Ghetko D, Prabu JR, Schulman BA

PDB-7b5r: 
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: CUL1-RBX1-SKP1-SKP2-CKSHS1-Cyclin A-CDK2-p27
Method: single particle / : Horn-Ghetko D, Prabu JR, Schulman BA
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