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Recent 3DEM papers
-Adipogenin promotes the development of lipid droplets by binding a dodecameric seipin complex.
Science, Vol. 390, Issue 6773, Page eadr9755, Year 2025
Chao Li / Xue-Nan Sun / Jan-Bernd Funcke / Lauri Vanharanta / Xavier Prasanna / Kaitlynn Gov / Yan Li / Megan Virostek / Chanmin Joung / Nolwenn Joffin ...Chao Li / Xue-Nan Sun / Jan-Bernd Funcke / Lauri Vanharanta / Xavier Prasanna / Kaitlynn Gov / Yan Li / Megan Virostek / Chanmin Joung / Nolwenn Joffin / Kristiina Kanerva / Abel Szkalisity / Waldemar Kulig / Leon Straub / Shiuhwei Chen / Joselin Velasco / Ayanna Cobb / Davide La Padula / May-Yun Wang / Toshiharu Onodera / Csaba Vörös / Dae-Seok Kim / Min Kim / Oleg Varlamov / Yang Li / Chen Liu / Andrea R Nawrocki / Shangang Zhao / Da Young Oh / Zhao V Wang / Ruth Gordillo / Joel M Goodman / R Max Wynn / W Mike Henne / Ilpo Vattulainen / Yan Han / Elina Ikonen / Philipp E Scherer
Methods: EM (single particle)
-Synthetic α-synuclein fibrils replicate in mice causing MSA-like pathology.
Nature, Year 2025
Domenic Burger / Marianna Kashyrina / Lukas van den Heuvel / Hortense de La Seiglière / Amanda J Lewis / Francesco De Nuccio / Inayathulla Mohammed / Jérémy Verchère / Cécile Feuillie / Mélanie Berbon ...Domenic Burger / Marianna Kashyrina / Lukas van den Heuvel / Hortense de La Seiglière / Amanda J Lewis / Francesco De Nuccio / Inayathulla Mohammed / Jérémy Verchère / Cécile Feuillie / Mélanie Berbon / Marie-Laure Arotcarena / Aude Retailleau / Erwan Bezard / Marie-Hélène Canron / Wassilios G Meissner / Antoine Loquet / Luc Bousset / Christel Poujol / K Peter R Nilsson / Florent Laferrière / Thierry Baron / Dario Domenico Lofrumento / Francesca De Giorgi / Henning Stahlberg / François Ichas
Methods: EM (helical sym.)
+Atomically accurate de novo design of antibodies with RFdiffusion.
+Structural snapshots capture nucleotide release at the μ-opioid receptor.
+The Specificity of RNA Packaging in Isometric RNA Plant Viruses is Principally Determined by Replication.
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-Feb 9, 2022. New format data for meta-information of EMDB entries
New format data for meta-information of EMDB entries
- Version 3 of the EMDB header file is now the official format.
- The previous official version 1.9 will be removed from the archive.
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wwPDB to switch to version 3 of the EMDB data model
-Oct 5, 2021. Nobel Prize for mechanically activated and temperature-gated ion channels
Nobel Prize for mechanically activated and temperature-gated ion channels
- The Nobel Prize in Physiology or Medicine 2021 was awarded jointly to David Julius and Ardem Patapoutian "for their discoveries of receptors for temperature and touch."
- EM Navigator can help to find cryo-EM structure data by both pioneers.
External links:
The Nobel Prize in Physiology or Medicine 2021 - NobelPrize.org /
Structure data by Ardem Patapoutian /
Structure data by David Julius
+Aug 12, 2020. Covid-19 info
+Mar 5, 2020. Novel coronavirus structure data
+Jul 5, 2019. Downlodablable text data
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