Author results

1RCS
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NMR STUDY OF TRP REPRESSOR-OPERATOR DNA COMPLEX
Descriptor:DNA (5'-D(*CP*GP*TP*AP*CP*TP*AP*GP*TP*TP*AP*AP*CP*TP*AP*GP*TP*AP*CP*G)-3'), TRP REPRESSOR, TRYPTOPHAN
Authors:Zhao, D., Zheng, Z.
Deposit date:1995-05-12
Release date:1996-06-20
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The solution structures of the trp repressor-operator DNA complex.
J.Mol.Biol., 238, 1994
1WRS
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NMR STUDY OF HOLO TRP REPRESSOR
Descriptor:HOLO TRP REPRESSOR, TRYPTOPHAN
Authors:Zhao, D., Zheng, Z.
Deposit date:1995-05-12
Release date:1996-06-20
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Refined solution structures of the Escherichia coli trp holo- and aporepressor.
J.Mol.Biol., 229, 1993
1WRT
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NMR STUDY OF APO TRP REPRESSOR
Descriptor:APO TRP REPRESSOR
Authors:Zhao, D., Zheng, Z.
Deposit date:1995-05-12
Release date:1996-06-20
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Refined solution structures of the Escherichia coli trp holo- and aporepressor.
J.Mol.Biol., 229, 1993
2QZ7
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THE CRYSTAL STRUCTURE OF A HOMOLOGUE OF TELLURIDE RESISTANCE PROTEIN (TERD), SCO6318 FROM STREPTOMYCES COELICOLOR A3(2)
Descriptor:Uncharacterized protein SCO6318, SODIUM ION, 1,2-ETHANEDIOL
Authors:Tan, K., Xu, X., Zheng, Z., Savchenko, A., Edwards, A., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
Deposit date:2007-08-16
Release date:2007-08-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The crystal structure of a homologue of telluride resistance protein (TerD), SCO6318 from Streptomyces coelicolor A3(2).
To be Published
3OFI
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CRYSTAL STRUCTURE OF HUMAN INSULIN-DEGRADING ENZYME IN COMPLEX WITH UBIQUITIN
Descriptor:Insulin-degrading enzyme, Ubiquitin, ZINC ION, ...
Authors:Kalas, V., Ralat, L.A., Tang, W.-J.
Deposit date:2010-08-15
Release date:2010-09-08
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Ubiquitin is a novel substrate for human insulin-degrading enzyme.
J.Mol.Biol., 406, 2011
3LKJ
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SMALL MOLECULE INHIBITION OF THE TNF FAMILY CYOKINE CD40 LIGAND THROUGH A SUBUNIT FRACTURE MECHANISM
Descriptor:CD40 ligand, N-ACETYL-D-GLUCOSAMINE, (2R)-{[(2'-[(biphenyl-3-ylmethyl)carbamoyl]-6'-{[(2R)-2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl]carbonyl}-6-{[(2R)-2-(1H-pyrrol-1-ylmethyl)pyrrolidin-1-yl]carbonyl}-4,4'-bipyridin-2-yl)carbonyl]amino}(cyclohexyl)ethanoic acid
Authors:Silvian, L.F., Whitty, A.
Deposit date:2010-01-27
Release date:2011-02-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Small Molecule Inhibition of the TNF Family Cytokine CD40 Ligand through a Subunit Fracture Mechanism.
Acs Chem.Biol., 6, 2011
3MQ0
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CRYSTAL STRUCTURE OF AGOBACTERIUM TUMEFACIENS REPRESSOR BLCR
Descriptor:Transcriptional repressor of the blcABC operon
Authors:Chen, L.
Deposit date:2010-04-27
Release date:2011-03-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.793 Å)
Cite:The Agrobacterium tumefaciens Transcription Factor BlcR Is Regulated via Oligomerization.
J.Biol.Chem., 286, 2011
3SL3
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CRYSTAL STRUCTURE OF THE APO FORM OF THE CATALYTIC DOMAIN OF PDE4D2
Descriptor:cAMP-specific 3',5'-cyclic phosphodiesterase 4D, 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ...
Authors:Feil, S.F.
Deposit date:2011-06-24
Release date:2011-10-26
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Thiophene inhibitors of PDE4: Crystal structures show a second binding mode at the catalytic domain of PDE4D2.
Bioorg.Med.Chem.Lett., 21, 2011
3SL4
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF PDE4D2 WITH COMPOUND 10D
Descriptor:cAMP-specific 3',5'-cyclic phosphodiesterase 4D, ZINC ION, 1,2-ETHANEDIOL, ...
Authors:Feil, S.F.
Deposit date:2011-06-24
Release date:2011-10-26
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Thiophene inhibitors of PDE4: Crystal structures show a second binding mode at the catalytic domain of PDE4D2.
Bioorg.Med.Chem.Lett., 21, 2011
3SL5
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF PDE4D2 COMPLEXED WITH COMPOUND 10D
Descriptor:cAMP-specific 3',5'-cyclic phosphodiesterase 4D, ZINC ION, diethyl 2-[(thiophen-2-ylacetyl)amino]-4,7-dihydrothieno[2,3-c]pyridine-3,6(5H)-dicarboxylate, ...
Authors:Feil, S.F.
Deposit date:2011-06-24
Release date:2011-10-26
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Thiophene inhibitors of PDE4: Crystal structures show a second binding mode at the catalytic domain of PDE4D2.
Bioorg.Med.Chem.Lett., 21, 2011
3SL6
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF PDE4D2 WITH COMPOUND 12C
Descriptor:cAMP-specific 3',5'-cyclic phosphodiesterase 4D, ZINC ION, 1,2-ETHANEDIOL, ...
Authors:Feil, S.F.
Deposit date:2011-06-24
Release date:2011-10-26
Last modified:2011-12-14
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Thiophene inhibitors of PDE4: Crystal structures show a second binding mode at the catalytic domain of PDE4D2.
Bioorg.Med.Chem.Lett., 21, 2011
3SL8
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF PDE4D2 WITH COMPOUND 10O
Descriptor:cAMP-specific 3',5'-cyclic phosphodiesterase 4D, 1,2-ETHANEDIOL, ZINC ION, ...
Authors:Feil, S.F.
Deposit date:2011-06-24
Release date:2011-10-26
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Thiophene inhibitors of PDE4: Crystal structures show a second binding mode at the catalytic domain of PDE4D2.
Bioorg.Med.Chem.Lett., 21, 2011
3RO2
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STRUCTURES OF THE LGN/NUMA COMPLEX
Descriptor:G-protein-signaling modulator 2, peptide of Nuclear mitotic apparatus protein 1, GLYCEROL
Authors:Shang, Y., Wei, Z.
Deposit date:2011-04-25
Release date:2012-03-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:LGN/mInsc and LGN/NuMA complex structures suggest distinct functions in asymmetric cell division for the Par3/mInsc/LGN and G[alpha]i/LGN/NuMA pathways
Mol.Cell, 43, 2011
3RO3
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CRYSTAL STRUCTURE OF LGN/MINSCUTEABLE COMPLEX
Descriptor:G-protein-signaling modulator 2, peptide of Protein inscuteable homolog, GLYCEROL, ...
Authors:Zhu, J., Wen, W., Shang, Y., Wei, Z., Pan, Z., Wang, W., Zhang, M.
Deposit date:2011-04-25
Release date:2012-03-07
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:LGN/mInsc and LGN/NuMA complex structures suggest distinct functions in asymmetric cell division for the Par3/mInsc/LGN and G[alpha]i/LGN/NuMA pathways
Mol.Cell, 43, 2011
3V3E
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CRYSTAL STRUCTURE OF THE HUMAN NUR77 LIGAND-BINDING DOMAIN
Descriptor:Nuclear receptor subfamily 4 group A member 1, GLYCEROL
Authors:Zhang, Q., Shi, C., Yang, K., Chen, Y., Zhan, Y., Wu, Q., Lin, T.
Deposit date:2011-12-13
Release date:2012-09-26
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:The orphan nuclear receptor Nur77 regulates LKB1 localization and activates AMPK
Nat.Chem.Biol., 8, 2012
3V3Q
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CRYSTAL STRUCTURE OF HUMAN NUR77 LIGAND-BINDING DOMAIN IN COMPLEX WITH ETHYL 2-[2,3,4 TRIMETHOXY-6(1-OCTANOYL)PHENYL]ACETATE
Descriptor:Nuclear receptor subfamily 4 group A member 1, ethyl (2,3,4-trimethoxy-6-octanoylphenyl)acetate, GLYCEROL, ...
Authors:Zhang, Q., Shi, C., Yang, K., Chen, Y., Zhan, Y., Wu, Q., Lin, T.
Deposit date:2011-12-14
Release date:2012-09-26
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:The orphan nuclear receptor Nur77 regulates LKB1 localization and activates AMPK
Nat.Chem.Biol., 8, 2012
4JHA
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CRYSTAL STRUCTURE OF RSV-NEUTRALIZING HUMAN ANTIBODY D25
Descriptor:D25 antigen-binding fragment heavy chain, D25 light chain
Authors:Mclellan, J.S., Chen, M., Leung, S., Graepel, K.W., Du, X., Yang, Y., Zhou, T., Baxa, U., Yasuda, E., Beaumont, T., Kumar, A., Modjarrad, K., Zheng, Z., Zhao, M., Xia, N., Kwong, P.D., Graham, B.S.
Deposit date:2013-03-04
Release date:2013-05-01
Last modified:2013-06-12
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of RSV fusion glycoprotein trimer bound to a prefusion-specific neutralizing antibody.
Science, 340, 2013
4JHW
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CRYSTAL STRUCTURE OF RESPIRATORY SYNCYTIAL VIRUS FUSION GLYCOPROTEIN STABILIZED IN THE PREFUSION CONFORMATION BY HUMAN ANTIBODY D25
Descriptor:D25 antigen-binding fragment heavy chain, D25 light chain, Fusion glycoprotein F0
Authors:Mclellan, J.S., Chen, M., Leung, S., Graepel, K.W., Du, X., Yang, Y., Zhou, T., Baxa, U., Yasuda, E., Beaumont, T., Kumar, A., Modjarrad, K., Zheng, Z., Zhao, M., Xia, N., Kwong, P.D., Graham, B.S.
Deposit date:2013-03-05
Release date:2013-05-01
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structure of RSV fusion glycoprotein trimer bound to a prefusion-specific neutralizing antibody.
Science, 340, 2013
4JYM
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CRYSTAL STRUCTURE OF KAI2 IN COMPLEX WITH 3-METHYL-2H-FURO[2,3-C]PYRAN-2-ONE
Descriptor:Hydrolase, alpha/beta fold family protein, 3-methyl-2H-furo[2,3-c]pyran-2-one
Authors:Guo, Y., Zheng, Z., Noel, J.P.
Deposit date:2013-03-30
Release date:2013-05-08
Last modified:2019-08-28
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Smoke-derived karrikin perception by the alpha/beta-hydrolase KAI2 from Arabidopsis.
Proc.Natl.Acad.Sci.USA, 110, 2013
4JYP
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CRYSTAL STRUCTURE OF KAI2 APO FORM
Descriptor:Hydrolase, alpha/beta fold family protein
Authors:Guo, Y., Zheng, Z., Noel, J.P.
Deposit date:2013-03-31
Release date:2013-05-08
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Smoke-derived karrikin perception by the alpha/beta-hydrolase KAI2 from Arabidopsis.
Proc.Natl.Acad.Sci.USA, 110, 2013
4K3J
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CRYSTAL STRUCTURE OF ONARTUZUMAB FAB IN COMPLEX WITH MET AND HGF-BETA
Descriptor:Hepatocyte growth factor, Hepatocyte growth factor beta chain, Onartuzumab Fab heavy chain, ...
Authors:Ma, X., Starovasnik, M.A.
Deposit date:2013-04-10
Release date:2013-08-28
Last modified:2014-08-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Monovalent antibody design and mechanism of action of onartuzumab, a MET antagonist with anti-tumor activity as a therapeutic agent.
Proc.Natl.Acad.Sci.USA, 110, 2013
4MMQ
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CRYSTAL STRUCTURE OF PREFUSION-STABILIZED RSV F VARIANT DS
Descriptor:Fusion glycoprotein F2, Fusion glycoprotein F1 fused with Fibritin trimerization domain, SULFATE ION
Authors:Mclellan, J.S., Joyce, M.G., Stewart-Jones, G.B.E., Sastry, M., Yang, Y., Graham, B.S., Kwong, P.D.
Deposit date:2013-09-09
Release date:2013-11-20
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (3.253 Å)
Cite:Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus.
Science, 342, 2013
4MMR
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CRYSTAL STRUCTURE OF PREFUSION-STABILIZED RSV F VARIANT CAV1 AT PH 9.5
Descriptor:Fusion glycoprotein F2, Fusion glycoprotein F1 fused with Fibritin trimerization domain
Authors:Stewart-Jones, G.B.E., McLellan, J.S., Joyce, M.G., Sastry, M., Yang, Y., Graham, B.S., Kwong, P.D.
Deposit date:2013-09-09
Release date:2013-11-20
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus.
Science, 342, 2013
4MMS
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CRYSTAL STRUCTURE OF PREFUSION-STABILIZED RSV F VARIANT CAV1 AT PH 5.5
Descriptor:Fusion glycoprotein F2, Fusion glycoprotein F1 fused with Fibritin trimerization domain, SULFATE ION
Authors:Mclellan, J.S., Joyce, M.G., Stewart-Jones, G.B.E., Sastry, M., Yang, Y., Graham, B.S., Kwong, P.D.
Deposit date:2013-09-09
Release date:2013-11-20
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.397 Å)
Cite:Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus.
Science, 342, 2013
4MMT
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CRYSTAL STRUCTURE OF PREFUSION-STABILIZED RSV F VARIANT DS-CAV1 AT PH 9.5
Descriptor:Fusion glycoprotein F2, Fusion glycoprotein F1 fused with Fibritin trimerization domain
Authors:Joyce, M.G., Mclellan, J.S., Stewart-Jones, G.B.E., Sastry, M., Yang, Y., Graham, B.S., Kwong, P.D.
Deposit date:2013-09-09
Release date:2013-11-20
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus.
Science, 342, 2013
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