5YJ4

structure for the protective mutant G127V of Human prion protein

Summary for 5YJ4

• Entry DOI: 10.2210/pdb5yj4/pdb
• Descriptor: Major prion protein (1 entity in total)
• Functional Keywords: prion disease, g127v mutant, disease-resistance, membrane protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 16285.22

Authors

Zheng, Z.,Lin, D. (deposition date: 2017-10-07, release date: 2018-04-11, Last modification date: 2023-06-14)

• Primary citation: Zheng, Z.,Zhang, M.,Wang, Y.,Ma, R.,Guo, C.,Feng, L.,Wu, J.,Yao, H.,Lin, D.; Structural basis for the complete resistance of the human prion protein mutant G127V to prion disease.; Sci Rep, 8:13211-13211, 2018; PubMed: 30181558; DOI: 10.1038/s41598-018-31394-6

Experimental method

SOLUTION NMR