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4MMR

Crystal Structure of Prefusion-stabilized RSV F Variant Cav1 at pH 9.5

Summary for 4MMR
Entry DOI10.2210/pdb4mmr/pdb
Related4JHW 4MMQ 4MMS 4MMT 4MMU 4MMV
DescriptorFusion glycoprotein F2, Fusion glycoprotein F1 fused with Fibritin trimerization domain (2 entities in total)
Functional Keywordsfusion, membrane, viral protein
Biological sourceHuman respiratory syncytial virus A2
More
Cellular locationVirion membrane; Single-pass type I membrane protein: P03420
Virion : P10104
Total number of polymer chains2
Total formula weight54792.43
Authors
Stewart-Jones, G.B.E.,McLellan, J.S.,Joyce, M.G.,Sastry, M.,Yang, Y.,Graham, B.S.,Kwong, P.D. (deposition date: 2013-09-09, release date: 2013-11-20, Last modification date: 2021-06-02)
Primary citationMcLellan, J.S.,Chen, M.,Joyce, M.G.,Sastry, M.,Stewart-Jones, G.B.,Yang, Y.,Zhang, B.,Chen, L.,Srivatsan, S.,Zheng, A.,Zhou, T.,Graepel, K.W.,Kumar, A.,Moin, S.,Boyington, J.C.,Chuang, G.Y.,Soto, C.,Baxa, U.,Bakker, A.Q.,Spits, H.,Beaumont, T.,Zheng, Z.,Xia, N.,Ko, S.Y.,Todd, J.P.,Rao, S.,Graham, B.S.,Kwong, P.D.
Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus.
Science, 342:592-598, 2013
Cited by
PubMed: 24179220
DOI: 10.1126/science.1243283
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.1 Å)
Structure validation

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