4MMR
Crystal Structure of Prefusion-stabilized RSV F Variant Cav1 at pH 9.5
Summary for 4MMR
Entry DOI | 10.2210/pdb4mmr/pdb |
Related | 4JHW 4MMQ 4MMS 4MMT 4MMU 4MMV |
Descriptor | Fusion glycoprotein F2, Fusion glycoprotein F1 fused with Fibritin trimerization domain (2 entities in total) |
Functional Keywords | fusion, membrane, viral protein |
Biological source | Human respiratory syncytial virus A2 More |
Cellular location | Virion membrane; Single-pass type I membrane protein: P03420 Virion : P10104 |
Total number of polymer chains | 2 |
Total formula weight | 54792.43 |
Authors | Stewart-Jones, G.B.E.,McLellan, J.S.,Joyce, M.G.,Sastry, M.,Yang, Y.,Graham, B.S.,Kwong, P.D. (deposition date: 2013-09-09, release date: 2013-11-20, Last modification date: 2021-06-02) |
Primary citation | McLellan, J.S.,Chen, M.,Joyce, M.G.,Sastry, M.,Stewart-Jones, G.B.,Yang, Y.,Zhang, B.,Chen, L.,Srivatsan, S.,Zheng, A.,Zhou, T.,Graepel, K.W.,Kumar, A.,Moin, S.,Boyington, J.C.,Chuang, G.Y.,Soto, C.,Baxa, U.,Bakker, A.Q.,Spits, H.,Beaumont, T.,Zheng, Z.,Xia, N.,Ko, S.Y.,Todd, J.P.,Rao, S.,Graham, B.S.,Kwong, P.D. Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus. Science, 342:592-598, 2013 Cited by PubMed: 24179220DOI: 10.1126/science.1243283 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
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