8IX3

Cryo-EM structure of SARS-CoV-2 BA.4/5 spike protein in complex with 1G11 (local refinement)

Summary for 8IX3

• Entry DOI: 10.2210/pdb8ix3/pdb
• EMDB information: 35788
• Descriptor: light chain of 1G11, heavy chain of 1G11, BA.4/5 variant spike protein (3 entities in total)
• Functional Keywords: sars-cov-2, neutralizing antibody, cryo-em, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 3
• Total formula weight: 49351.15

Authors

Sun, H.,Jiang, Y.,Zheng, Z.,Zheng, Q.,Li, S. (deposition date: 2023-03-31, release date: 2023-11-15, Last modification date: 2023-12-13)

• Primary citation: Sun, H.,Wang, Y.,Chen, X.,Jiang, Y.,Wang, S.,Huang, Y.,Liu, L.,Li, Y.,Lan, M.,Guo, H.,Yuan, Q.,Zhang, Y.,Li, T.,Yu, H.,Gu, Y.,Zhang, J.,Li, S.,Zheng, Z.,Zheng, Q.,Xia, N.; Structural basis for broad neutralization of human antibody against Omicron sublineages and evasion by XBB variant.; J.Virol., 97:e0113723-e0113723, 2023; PubMed: 37855619; DOI: 10.1128/jvi.01137-23

Experimental method

ELECTRON MICROSCOPY (3.98 Å)