8IX3

Cryo-EM structure of SARS-CoV-2 BA.4/5 spike protein in complex with 1G11 (local refinement)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (L)	light chain of 1G11	polymer	107	11629.0	1		Homo sapiens
2	B (H)	heavy chain of 1G11	polymer	125	13772.2	1		Homo sapiens
3	C (G)	BA.4/5 variant spike protein	polymer	213	23950.0	1	UniProt (P0DTC2) Pfam (PF09408)	Severe acute respiratory syndrome coronavirus 2	Spike protein S2'

Sequence modifications

G: 333 - 545 (UniProt: P0DTC2)

PDB	External Database	Details
Asp 339	Gly 339	variant
Phe 371	Ser 371	variant
Pro 373	Ser 373	variant
Phe 375	Ser 375	variant
Ala 376	Thr 376	variant
Asn 405	Asp 405	variant
Ser 408	Arg 408	variant
Asn 417	Lys 417	variant
Lys 440	Asn 440	variant
Arg 452	Leu 452	variant
Asn 477	Ser 477	variant
Lys 478	Thr 478	variant
Ala 484	Glu 484	variant
Val 486	Phe 486	variant
Arg 498	Gln 498	variant
Tyr 501	Asn 501	variant
His 505	Tyr 505	variant
Lys 527	Pro 527	variant
-	Lys 529	deletion
-	Ser 530	deletion
-	Thr 531	deletion
-	Asn 532	deletion
-	Leu 533	deletion
-	Val 534	deletion
-	Lys 535	deletion
-	Asn 536	deletion
-	Lys 537	deletion
-	Cys 538	deletion
-	Val 539	deletion
-	Asn 540	deletion

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	49351.2
All*	Total formula weight	49351.2

*Water molecules are not included.