Author results

2DBQ
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CRYSTAL STRUCTURE OF GLYOXYLATE REDUCTASE (PH0597) FROM PYROCOCCUS HORIKOSHII OT3, COMPLEXED WITH NADP (I41)
Descriptor:Glyoxylate reductase, SULFATE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Yoshikawa, S., Arai, R., Kinoshita, Y., Uchikubo-Kamo, T., Akasaka, R., Terada, T., Shirouzu, M., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-12-16
Release date:2006-06-16
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of archaeal glyoxylate reductase from Pyrococcus horikoshii OT3 complexed with nicotinamide adenine dinucleotide phosphate.
Acta Crystallogr.,Sect.D, 63, 2007
2DBR
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CRYSTAL STRUCTURE OF GLYOXYLATE REDUCTASE (PH0597) FROM PYROCOCCUS HORIKOSHII OT3, COMPLEXED WITH NADP (P1)
Descriptor:Glyoxylate reductase, SULFATE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Yoshikawa, S., Arai, R., Kinoshita, Y., Uchikubo-Kamo, T., Akasaka, R., Terada, T., Shirouzu, M., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-12-16
Release date:2006-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Structure of archaeal glyoxylate reductase from Pyrococcus horikoshii OT3 complexed with nicotinamide adenine dinucleotide phosphate.
Acta Crystallogr.,Sect.D, 63, 2007
2DBZ
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CRYSTAL STRUCTURE OF GLYOXYLATE REDUCTASE (PH0597) FROM PYROCOCCUS HORIKOSHII OT3, COMPLEXED WITH NADP (P61)
Descriptor:Glyoxylate reductase, SULFATE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Yoshikawa, S., Arai, R., Kinoshita, Y., Uchikubo-Kamo, T., Akasaka, R., Terada, T., Shirouzu, M., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-12-16
Release date:2006-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structure of archaeal glyoxylate reductase from Pyrococcus horikoshii OT3 complexed with nicotinamide adenine dinucleotide phosphate.
Acta Crystallogr.,Sect.D, 63, 2007
2EB2
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CRYSTAL STRUCTURE OF MUTATED EGFR KINASE DOMAIN (G719S)
Descriptor:Epidermal growth factor receptor
Authors:Yoshikawa, S., Kukimoto-Niino, M., Chen, L., Liu, Z.J., Wang, B.C., Shirouzu, M., Senba, K., Yamamoto, T., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-02-06
Release date:2008-02-12
Last modified:2012-03-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for the altered drug sensitivities of non-small cell lung cancer-associated mutants of human epidermal growth factor receptor
Oncogene, 2012
2EB3
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CRYSTAL STRUCTURE OF MUTATED EGFR KINASE DOMAIN (L858R) IN COMPLEX WITH AMPPNP
Descriptor:Epidermal growth factor receptor, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Yoshikawa, S., Kukimoto-Niino, M., Shirouzu, M., Senba, K., Yamamoto, T., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-02-06
Release date:2008-02-12
Last modified:2012-03-07
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:Structural basis for the altered drug sensitivities of non-small cell lung cancer-associated mutants of human epidermal growth factor receptor
Oncogene, 2012
3HJN
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CRYSTAL STRUCTURE OF THYMIDYLATE KINASE IN COMPLEX WITH DTDP AND ADP FROM THERMOTOGA MARITIMA
Descriptor:Thymidylate kinase, ADENOSINE-5'-DIPHOSPHATE, THYMIDINE-5'-DIPHOSPHATE, ...
Authors:Yoshikawa, S., Nakagawa, N., Shirouzu, M., Yokoyama, S., Kuramitsu, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2009-05-22
Release date:2009-06-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of thymidylate kinase in complex with dTDP and ADP from Thermotoga maritima
To be Published
3VJN
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CRYSTAL STRUCTURE OF THE MUTATED EGFR KINASE DOMAIN (G719S/T790M) IN COMPLEX WITH AMPPNP.
Descriptor:Epidermal growth factor receptor, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Yoshikawa, S., Kukimoto-Niino, M., Shirouzu, M., Semba, K., Yamamoto, T., Yokoyama, S.
Deposit date:2011-10-27
Release date:2012-03-07
Last modified:2013-06-26
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Structural basis for the altered drug sensitivities of non-small cell lung cancer-associated mutants of human epidermal growth factor receptor.
Oncogene, 32, 2013
3VJO
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CRYSTAL STRUCTURE OF THE WILD-TYPE EGFR KINASE DOMAIN IN COMPLEX WITH AMPPNP.
Descriptor:Epidermal growth factor receptor, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Yoshikawa, S., Kukimoto-Niino, M., Shirouzu, M., Semba, K., Yamamoto, T., Yokoyama, S.
Deposit date:2011-10-27
Release date:2012-03-07
Last modified:2013-06-26
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Structural basis for the altered drug sensitivities of non-small cell lung cancer-associated mutants of human epidermal growth factor receptor.
Oncogene, 32, 2013
2CZG
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CRYSTAL STRUCTURE OF PROBABLE PHOSPHORIBOSYLGLYCINAMIDE FORMYL TRANSFERASE (PH0318) FROM PYROCOCCUS HORIKOSHII OT3
Descriptor:phosphoribosylglycinamide formyl transferase, SULFATE ION, GLYCEROL
Authors:Yoshikawa, S., Arai, R., Kamo-Uchikubo, T., Shirouzu, M., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-07-13
Release date:2006-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structure of Probable phosphoribosylglycinamide formyl transferase (PH0318) from Pyrococcus horikoshii OT3
To be Published
2DBS
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CRYSTAL STRUCTURE OF A HYPOTHETICAL PROTEIN TTHC002 FROM THERMUS THERMOPHILUS HB8
Descriptor:hypothetical protein TTHC002
Authors:Yoshikawa, S., Arai, R., Kamo-Uchikubo, T., Fusatomi, E., Akasaka, R., Bessho, Y., Murayama, K., Terada, T., Shirouzu, M., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-12-16
Release date:2006-06-16
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of a hypothetical protein TTHC002 from Thermus thermophilus HB8
To be Published
2DWC
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CRYSTAL STRUCTURE OF PROBABLE PHOSPHORIBOSYLGLYCINAMIDE FORMYL TRANSFERASE FROM PYROCOCCUS HORIKOSHII OT3 COMPLEXED WITH ADP
Descriptor:433aa long hypothetical phosphoribosylglycinamide formyl transferase, SULFATE ION, ADENOSINE-5'-DIPHOSPHATE
Authors:Yoshikawa, S., Arai, R., Kamo-Uchikubo, T., Shirouzu, M., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-08-10
Release date:2007-02-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of Probable phosphoribosylglycinamide formyl transferase from Pyrococcus horikoshii OT3 complexed with ADP
To be Published
2ZKW
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CRYSTAL STRUCTURE OF HUMAN CU-ZN SUPEROXIDE DISMUTASE MUTANT G85R IN SPACE GROUP P21
Descriptor:Superoxide dismutase [Cu-Zn], COPPER (I) ION, ZINC ION
Authors:Yoshikawa, S., Kukimoto-Niino, M., Ito, K., Chen, L., Fu, Z.Q., Chrzas, J., Wang, B.C., Shirouzu, M., Urushitani, M., Takahashi, R., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2008-03-31
Release date:2009-03-24
Last modified:2012-04-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of human Cu-Zn superoxide dismutase mutant G85R in space group P21
To be Published
2ZKX
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CRYSTAL STRUCTURE OF HUMAN CU-ZN SUPEROXIDE DISMUTASE MUTANT G85R IN SPACE GROUP I212121
Descriptor:Superoxide dismutase [Cu-Zn], COPPER (I) ION, ZINC ION
Authors:Yoshikawa, S., Kukimoto-Niino, M., Ito, K., Chen, L., Fu, Z.Q., Chrzas, J., Wang, B.C., Shirouzu, M., Urushitani, M., Takahashi, R., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2008-03-31
Release date:2009-03-24
Last modified:2012-04-04
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:Crystal structure of human Cu-Zn superoxide dismutase mutant G85R in space group I212121
To be Published
2ZKY
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CRYSTAL STRUCTURE OF HUMAN CU-ZN SUPEROXIDE DISMUTASE MUTANT G93A
Descriptor:Superoxide dismutase [Cu-Zn], ZINC ION
Authors:Yoshikawa, S., Kukimoto-Niino, M., Ito, K., Shirouzu, M., Urushitani, M., Takahashi, R., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2008-03-31
Release date:2009-03-24
Last modified:2012-04-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of human Cu-Zn superoxide dismutase mutant G93A
To be Published
2ZV2
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CRYSTAL STRUCTURE OF HUMAN CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2, BETA, CAMKK2 KINASE DOMAIN IN COMPLEX WITH STO-609
Descriptor:Calcium/calmodulin-dependent protein kinase kinase 2, 7-oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic acid
Authors:Yoshikawa, S., Kukimoto-niino, M., Shirouzu, M., Suzuki, A., Lee, S., Minokoshi, Y., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2008-10-31
Release date:2009-11-03
Last modified:2013-11-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of the Ca2+/calmodulin-dependent protein kinase kinase in complex with the inhibitor STO-609
J.Biol.Chem., 286, 2011
3UG1
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CRYSTAL STRUCTURE OF THE MUTATED EGFR KINASE DOMAIN (G719S/T790M) IN THE APO FORM
Descriptor:Epidermal growth factor receptor, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
Authors:Parker, L.J., Handa, N., Yoshikawa, S., Kukimoto-Niino, M., Shirouzu, M., Yokoyama, S.
Deposit date:2011-11-02
Release date:2012-03-07
Last modified:2014-03-12
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural basis for the altered drug sensitivities of non-small cell lung cancer-associated mutants of human epidermal growth factor receptor
Oncogene, 32, 2013
3UG2
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CRYSTAL STRUCTURE OF THE MUTATED EGFR KINASE DOMAIN (G719S/T790M) IN COMPLEX WITH GEFITINIB
Descriptor:Epidermal growth factor receptor, Gefitinib, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
Authors:Parker, L.J., Handa, N., Yoshikawa, S., Kukimoto-Niino, M., Shirouzu, M., Yokoyama, S.
Deposit date:2011-11-02
Release date:2012-03-07
Last modified:2014-10-15
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for the altered drug sensitivities of non-small cell lung cancer-associated mutants of human epidermal growth factor receptor
Oncogene, 32, 2013
2CYX
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STRUCTURE OF HUMAN UBIQUITIN-CONJUGATING ENZYME E2 G2 (UBE2G2/UBC7)
Descriptor:Ubiquitin-conjugating enzyme E2 G2
Authors:Yoshikawa, S., Arai, R., Murayama, K., Imai, Y., Takahashi, R., Shirouzu, M., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-07-08
Release date:2006-04-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Structure of human ubiquitin-conjugating enzyme E2 G2 (UBE2G2/UBC7)
Acta Crystallogr.,Sect.F, 62, 2006
1OCC
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STRUCTURE OF BOVINE HEART CYTOCHROME C OXIDASE AT THE FULLY OXIDIZED STATE
Descriptor:CYTOCHROME C OXIDASE, COPPER (II) ION, MAGNESIUM ION, ...
Authors:Tsukihara, T., Aoyama, H., Yamashita, E., Tomizaki, T., Yamaguchi, H., Shinzawa-Itoh, K., Nakashima, R., Yaono, R., Yoshikawa, S.
Deposit date:1996-04-18
Release date:1996-12-07
Last modified:2018-03-21
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The whole structure of the 13-subunit oxidized cytochrome c oxidase at 2.8 A.
Science, 272, 1996
2MGZ
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SOLUTION STRUCTURE OF RBFOX FAMILY ASD-1 RRM AND SUP-12 RRM IN TERNARY COMPLEX WITH RNA
Descriptor:Protein ASD-1, isoform a, Protein SUP-12, ...
Authors:Takahashi, M., Kuwasako, K., Unzai, S., Tsuda, K., Yoshikawa, S., He, F., Kobayashi, N., Guntert, P., Shirouzu, M., Ito, T., Tanaka, A., Yokoyama, S., Hagiwara, M., Kuroyanagi, H., Muto, Y.
Deposit date:2013-11-12
Release date:2014-08-13
Last modified:2015-03-18
Method:SOLUTION NMR
Cite:RBFOX and SUP-12 sandwich a G base to cooperatively regulate tissue-specific splicing
Nat.Struct.Mol.Biol., 21, 2014
2RU3
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SOLUTION STRUCTURE OF C.ELEGANS SUP-12 RRM IN COMPLEX WITH RNA
Descriptor:Protein SUP-12, isoform a, RNA (5'-R(*GP*UP*GP*UP*GP*C)-3')
Authors:Takahashi, M., Kuwasako, K., Unzai, S., Tsuda, K., Yoshikawa, S., He, F., Kobayashi, N., Guntert, P., Shirouzu, M., Ito, T., Tanaka, A., Yokoyama, S., Hagiwara, M., Kuroyanagi, H., Muto, Y.
Deposit date:2013-11-12
Release date:2014-08-13
Last modified:2015-03-18
Method:SOLUTION NMR
Cite:RBFOX and SUP-12 sandwich a G base to cooperatively regulate tissue-specific splicing
Nat.Struct.Mol.Biol., 21, 2014
3A99
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STRUCTURE OF PIM-1 KINASE CRYSTALLIZED IN THE PRESENCE OF P27KIP1 CARBOXY-TERMINAL PEPTIDE
Descriptor:Proto-oncogene serine/threonine-protein kinase pim-1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Morishita, D., Takami, M., Yoshikawa, S., Katayama, R., Sato, S., Kukimoto-Niino, M., Umehara, T., Shirouzu, M., Sekimizu, K., Yokoyama, S., Fujita, N.
Deposit date:2009-10-22
Release date:2010-11-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Cell-permeable carboxyl-terminal p27(Kip1) peptide exhibits anti-tumor activity by inhibiting Pim-1 kinase
J.Biol.Chem., 286, 2011
5X19
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CO BOUND CYTOCHROME C OXIDASE AT 100 MICRO SEC AFTER PUMP LASER IRRADIATION TO RELEASE CO FROM O2 REDUCTION CENTER
Descriptor:Cytochrome c oxidase subunit 1, Cytochrome c oxidase subunit 2, Cytochrome c oxidase subunit 3, ...
Authors:Shimada, A., Kubo, M., Baba, S., Yamashita, K., Hirata, K., Ueno, G., Nomura, T., Kimura, T., Shinzawa-Itoh, K., Baba, J., Hatano, K., Eto, Y., Miyamoto, A., Murakami, H., Kumasaka, T., Owada, S., Tono, K., Yabashi, M., Yamaguchi, Y., Yanagisawa, S., Sakaguchi, M., Ogura, T., Komiya, R., Yan, J., Yamashita, E., Yamamoto, M., Ago, H., Yoshikawa, S., Tsukihara, T.
Deposit date:2017-01-25
Release date:2017-08-09
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A nanosecond time-resolved XFEL analysis of structural changes associated with CO release from cytochrome c oxidase.
Sci Adv, 3, 2017
5X1B
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CO BOUND CYTOCHROME C OXIDASE AT 20 NSEC AFTER PUMP LASER IRRADIATION TO RELEASE CO FROM O2 REDUCTION CENTER
Descriptor:Cytochrome c oxidase subunit 1, Cytochrome c oxidase subunit 2, Cytochrome c oxidase subunit 3, ...
Authors:Shimada, A., Kubo, M., Baba, S., Yamashita, K., Hirata, K., Ueno, G., Nomura, T., Kimura, T., Shinzawa-Itoh, K., Baba, J., Hatano, K., Eto, Y., Miyamoto, A., Murakami, H., Kumasaka, T., Owada, S., Tono, K., Yabashi, M., Yamaguchi, Y., Yanagisawa, S., Sakaguchi, M., Ogura, T., Komiya, R., Yan, J., Yamashita, E., Yamamoto, M., Ago, H., Yoshikawa, S., Tsukihara, T.
Deposit date:2017-01-25
Release date:2017-08-09
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A nanosecond time-resolved XFEL analysis of structural changes associated with CO release from cytochrome c oxidase.
Sci Adv, 3, 2017
5X1F
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CO BOUND CYTOCHROME C OXIDASE WITHOUT PUMP LASER IRRADIATION AT 278K
Descriptor:Cytochrome c oxidase subunit 1, Cytochrome c oxidase subunit 2, Cytochrome c oxidase subunit 3, ...
Authors:Shimada, A., Kubo, M., Baba, S., Yamashita, K., Hirata, K., Ueno, G., Nomura, T., Kimura, T., Shinzawa-Itoh, K., Baba, J., Hatano, K., Eto, Y., Miyamoto, A., Murakami, H., Kumasaka, T., Owada, S., Tono, K., Yabashi, M., Yamaguchi, Y., Yanagisawa, S., Sakaguchi, M., Ogura, T., Komiya, R., Yan, J., Yamashita, E., Yamamoto, M., Ago, H., Yoshikawa, S., Tsukihara, T.
Deposit date:2017-01-25
Release date:2017-08-09
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A nanosecond time-resolved XFEL analysis of structural changes associated with CO release from cytochrome c oxidase.
Sci Adv, 3, 2017
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