Solution structure of c.elegans SUP-12 RRM in complex with RNA

Summary for 2RU3

DescriptorProtein SUP-12, isoform a, RNA (5'-R(*GP*UP*GP*UP*GP*C)-3') (2 entities in total)
Functional Keywordssolution structure, protein-rna complex, rrm (rna recognition motif), rna binding protein-rna complex, rna binding protein/rna
Biological sourceCaenorhabditis elegans (nematode)
Total number of polymer chains2
Total molecular weight13334.95
Primary citation
Kuwasako, K.,Takahashi, M.,Unzai, S.,Tsuda, K.,Yoshikawa, S.,He, F.,Kobayashi, N.,Guntert, P.,Shirouzu, M.,Ito, T.,Tanaka, A.,Yokoyama, S.,Hagiwara, M.,Kuroyanagi, H.,Muto, Y.
RBFOX and SUP-12 sandwich a G base to cooperatively regulate tissue-specific splicing
Nat.Struct.Mol.Biol., 21:778-786, 2014
PubMed: 25132178 (PDB entries with the same primary citation)
DOI: 10.1038/nsmb.2870
MImport into Mendeley
Experimental method
NMR Information

Structure validation

ClashscoreRamachandran outliersSidechain outliersRNA backbone01.4%2.3%0.28MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures

More Asymmetric unit images

Molmil generated image of 2ru3
no rotation
Molmil generated image of 2ru3
rotated about x axis by 90°
Molmil generated image of 2ru3
rotated about y axis by 90°