5X19

CO bound cytochrome c oxidase at 100 micro sec after pump laser irradiation to release CO from O2 reduction center

Summary for 5X19

• Entry DOI: 10.2210/pdb5x19/pdb
• Related: 5X1B 5X1F
• Descriptor: Cytochrome c oxidase subunit 1, Cytochrome c oxidase subunit 7A1, mitochondrial, Cytochrome c oxidase subunit 7B, mitochondrial, ... (30 entities in total)
• Functional Keywords: cytochrome c oxidase, x-ray free electron laser, time-resolved analysis, proton pump, membrane protein, oxidoreductase
• Biological source: Bos taurus (Bovine); More
• Cellular location: Mitochondrion inner membrane; Multi-pass membrane protein: P00396 P68530 P00415; Mitochondrion inner membrane: P07470 P13183 P00430 P10175 P00423 P00426 P00428 P07471 P04038; Mitochondrion intermembrane space: P00429
• Total number of polymer chains: 26
• Total formula weight: 443274.46

Authors

Shimada, A.,Kubo, M.,Baba, S.,Yamashita, K.,Hirata, K.,Ueno, G.,Nomura, T.,Kimura, T.,Shinzawa-Itoh, K.,Baba, J.,Hatano, K.,Eto, Y.,Miyamoto, A.,Murakami, H.,Kumasaka, T.,Owada, S.,Tono, K.,Yabashi, M.,Yamaguchi, Y.,Yanagisawa, S.,Sakaguchi, M.,Ogura, T.,Komiya, R.,Yan, J.,Yamashita, E.,Yamamoto, M.,Ago, H.,Yoshikawa, S.,Tsukihara, T. (deposition date: 2017-01-25, release date: 2017-08-09, Last modification date: 2023-11-22)

• Primary citation: Shimada, A.,Kubo, M.,Baba, S.,Yamashita, K.,Hirata, K.,Ueno, G.,Nomura, T.,Kimura, T.,Shinzawa-Itoh, K.,Baba, J.,Hatano, K.,Eto, Y.,Miyamoto, A.,Murakami, H.,Kumasaka, T.,Owada, S.,Tono, K.,Yabashi, M.,Yamaguchi, Y.,Yanagisawa, S.,Sakaguchi, M.,Ogura, T.,Komiya, R.,Yan, J.,Yamashita, E.,Yamamoto, M.,Ago, H.,Yoshikawa, S.,Tsukihara, T.; A nanosecond time-resolved XFEL analysis of structural changes associated with CO release from cytochrome c oxidase.; Sci Adv, 3:e1603042-e1603042, 2017; PubMed: 28740863; DOI: 10.1126/sciadv.1603042

Experimental method

X-RAY DIFFRACTION (2.2 Å)