CO bound cytochrome c oxidase at 20 nsec after pump laser irradiation to release CO from O2 reduction center

Summary for 5X1B

Related5X19 5X1F
DescriptorCytochrome c oxidase subunit 1, Cytochrome c oxidase subunit 2, Cytochrome c oxidase subunit 3, ... (30 entities in total)
Functional Keywordscytochrome c oxidase, x-ray free electron laser, time-resolved analysis, proton pump, membrane protein, oxidoreductase
Biological sourceBos taurus (Bovine)
Cellular locationMitochondrion inner membrane; Multi-pass membrane protein P00396 P68530 P00415
Mitochondrion inner membrane P00423 P00426 P00428 P07471 P04038 P07470 P13183 P00430 P10175
Mitochondrion intermembrane space P00429
Total number of polymer chains26
Total molecular weight442964.12
Primary citation
Shimada, A.,Kubo, M.,Baba, S.,Yamashita, K.,Hirata, K.,Ueno, G.,Nomura, T.,Kimura, T.,Shinzawa-Itoh, K.,Baba, J.,Hatano, K.,Eto, Y.,Miyamoto, A.,Murakami, H.,Kumasaka, T.,Owada, S.,Tono, K.,Yabashi, M.,Yamaguchi, Y.,Yanagisawa, S.,Sakaguchi, M.,Ogura, T.,Komiya, R.,Yan, J.,Yamashita, E.,Yamamoto, M.,Ago, H.,Yoshikawa, S.,Tsukihara, T.
A nanosecond time-resolved XFEL analysis of structural changes associated with CO release from cytochrome c oxidase.
Sci Adv, 3:e1603042-e1603042, 2017
PubMed: 28740863 (PDB entries with the same primary citation)
DOI: 10.1126/sciadv.1603042
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.230101.1%5.3%2.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution