Author results

6WAQ
  • Download 6waq
  • View 6waq
Molmil generated image of 6waq
CRYSTAL STRUCTURE OF THE SARS-COV-1 RBD BOUND BY THE CROSS-REACTIVE SINGLE-DOMAIN ANTIBODY SARS VHH-72
Descriptor:nanobody SARS VHH-72, Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Wrapp, D., McLellan, J.S.
Deposit date:2020-03-25
Release date:2020-04-01
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies.
Cell, 181, 2020
6WAR
  • Download 6war
  • View 6war
Molmil generated image of 6war
CRYSTAL STRUCTURE OF THE MERS-COV RBD BOUND BY THE NEUTRALIZING SINGLE-DOMAIN ANTIBODY MERS VHH-55
Descriptor:Spike protein, nanobody MERS VHH-55, 2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Wrapp, D., Torres, G.M., McLellan, J.S.
Deposit date:2020-03-25
Release date:2020-04-08
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies.
Cell, 181, 2020
6U7K
  • Download 6u7k
  • View 6u7k
Molmil generated image of 6u7k
PREFUSION STRUCTURE OF PEDV SPIKE
Descriptor:Spike glycoprotein, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Wrapp, D., McLellan, J.S.
Deposit date:2019-09-03
Release date:2019-09-18
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.14 Å)
Cite:The 3.1-Angstrom Cryo-electron Microscopy Structure of the Porcine Epidemic Diarrhea Virus Spike Protein in the Prefusion Conformation.
J.Virol., 93, 2019
6VSB
  • Download 6vsb
  • View 6vsb
Molmil generated image of 6vsb
PREFUSION 2019-NCOV SPIKE GLYCOPROTEIN WITH A SINGLE RECEPTOR-BINDING DOMAIN UP
Descriptor:SARS-CoV-2 spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Wrapp, D., Wang, N., Corbett, K.S., Goldsmith, J.A., Hsieh, C., Abiona, O., Graham, B.S., McLellan, J.S.
Deposit date:2020-02-10
Release date:2020-02-26
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.46 Å)
Cite:Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation.
Science, 367, 2020
6XKL
  • Download 6xkl
  • View 6xkl
Molmil generated image of 6xkl
SARS-COV-2 HEXAPRO S ONE RBD UP
Descriptor:Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Wrapp, D., Hsieh, C.-L., Goldsmith, J.A., McLellan, J.S.
Deposit date:2020-06-26
Release date:2020-07-15
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.21 Å)
Cite:Structure-based Design of Prefusion-stabilized SARS-CoV-2 Spikes.
Biorxiv, 2020
6UOE
  • Download 6uoe
  • View 6uoe
Molmil generated image of 6uoe
3-25 FAB GERMLINE-REVERSION VARIANT BOUND TO AN HCMV GB-DERIVED PEPTIDE
Descriptor:3-25 Fab heavy chain, 3-25 Fab light chain, Envelope glycoprotein B, ...
Authors:Wrapp, D., McLellan, J.S.
Deposit date:2019-10-14
Release date:2020-07-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Characterization of a broadly neutralizing antibody that recognizes antigenic domain-2 of HCMV gB
To Be Published
5TP3
  • Download 5tp3
  • View 5tp3
Molmil generated image of 5tp3
CRYSTAL STRUCTURE OF THE RSV-NEUTRALIZING SINGLE-DOMAIN ANTIBODY F-VHH-4
Descriptor:F-VHH-4
Authors:Wrapp, D., Gilman, M.S.A., McLellan, J.S.
Deposit date:2016-10-19
Release date:2017-02-22
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (1.874 Å)
Cite:Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state.
Nat Commun, 8, 2017
6APD
  • Download 6apd
  • View 6apd
Molmil generated image of 6apd
CRYSTAL STRUCTURE OF RSV F BOUND BY AM22 AND THE INFANT ANTIBODY ADI-19425
Descriptor:Fusion glycoprotein F0,Envelope glycoprotein, AM22 Fab Heavy Chain,IGH@ protein, AM22 Fab Light Chain,Uncharacterized protein, ...
Authors:Wrapp, D., McLellan, J.S.
Deposit date:2017-08-17
Release date:2018-03-21
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Infants Infected with Respiratory Syncytial Virus Generate Potent Neutralizing Antibodies that Lack Somatic Hypermutation.
Immunity, 48, 2018
5VYH
  • Download 5vyh
  • View 5vyh
Molmil generated image of 5vyh
CRYSTAL STRUCTURE OF MERS-COV S1 N-TERMINAL DOMAIN
Descriptor:S protein, 2-acetamido-2-deoxy-beta-D-glucopyranose, FOLIC ACID, ...
Authors:Wang, N., Wrapp, D., Pallesen, J., Ward, A.B., McLellan, J.S.
Deposit date:2017-05-25
Release date:2017-08-30
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5VZR
  • Download 5vzr
  • View 5vzr
Molmil generated image of 5vzr
CRYSTAL STRUCTURE OF MERS-COV NEUTRALIZING ANTIBODY G4 FAB
Descriptor:G4 antibody heavy chain, G4 antibody light chain, GLYCEROL
Authors:Wang, N., Wrapp, D., McLellan, J.S.
Deposit date:2017-05-29
Release date:2017-08-30
Last modified:2019-12-11
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6ZOW
  • Download 6zow
  • View 6zow
Molmil generated image of 6zow
SARS-COV-2 SPIKE IN PREFUSION STATE
Descriptor:Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Martinez, M., Marabini, R., Carazo, J.M.
Deposit date:2020-07-07
Release date:2020-07-29
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Continuous flexibility analysis of SARS-CoV-2 Spike prefusion structures.
Biorxiv, 2020
6ZP5
  • Download 6zp5
  • View 6zp5
Molmil generated image of 6zp5
SARS-COV-2 SPIKE IN PREFUSION STATE (FLEXIBILITY ANALYSIS, 1-UP CLOSED CONFORMATION)
Descriptor:Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Martinez, M., Marabini, R., Carazo, J.M.
Deposit date:2020-07-08
Release date:2020-07-29
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Continuous flexibility analysis of SARS-CoV-2 Spike prefusion structures.
Biorxiv, 2020
6ZP7
  • Download 6zp7
  • View 6zp7
Molmil generated image of 6zp7
SARS-COV-2 SPIKE IN PREFUSION STATE (FLEXIBILITY ANALYSIS, 1-UP OPEN CONFORMATION)
Descriptor:Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Martinez, M., Marabini, R., Carazo, J.M.
Deposit date:2020-07-08
Release date:2020-07-29
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Continuous flexibility analysis of SARS-CoV-2 Spike prefusion structures.
Biorxiv, 2020
5TOJ
  • Download 5toj
  • View 5toj
Molmil generated image of 5toj
CRYSTAL STRUCTURE OF THE RSV F GLYCOPROTEIN IN COMPLEX WITH THE NEUTRALIZING SINGLE-DOMAIN ANTIBODY F-VHH-4
Descriptor:Fusion glycoprotein F0, Fibritin chimera, Single-domain antibody F-VHH-4, ...
Authors:Gilman, M.S.A., Kabeche, S.C., McLellan, J.S.
Deposit date:2016-10-17
Release date:2017-02-22
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state.
Nat Commun, 8, 2017
5TOK
  • Download 5tok
  • View 5tok
Molmil generated image of 5tok
CRYSTAL STRUCTURE OF THE RSV F GLYCOPROTEIN IN COMPLEX WITH THE NEUTRALIZING SINGLE-DOMAIN ANTIBODY F-VHH-L66
Descriptor:Fusion glycoprotein F0, Fibritin chimera, Single-domain antibody F-VHH-L66, ...
Authors:Gilman, M.S.A., Kabeche, S.C., McLellan, J.S.
Deposit date:2016-10-17
Release date:2017-02-22
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state.
Nat Commun, 8, 2017
5UDC
  • Download 5udc
  • View 5udc
Molmil generated image of 5udc
CRYSTAL STRUCTURE OF RSV F A2 BOUND TO MEDI8897
Descriptor:MEDI8897 Fab Heavy Chain, MEDI8897 Fab Light Chain, Fusion glycoprotein F0, ...
Authors:McLellan, J.S.
Deposit date:2016-12-26
Release date:2017-05-17
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:A highly potent extended half-life antibody as a potential RSV vaccine surrogate for all infants.
Sci Transl Med, 9, 2017
5UDD
  • Download 5udd
  • View 5udd
Molmil generated image of 5udd
CRYSTAL STRUCTURE OF RSV F B9320 BOUND TO MEDI8897
Descriptor:Fusion glycoprotein F0, MEDI8897 Fab Heavy Chain, MEDI8897 Fab Light Chain, ...
Authors:McLellan, J.S.
Deposit date:2016-12-26
Release date:2017-05-17
Method:X-RAY DIFFRACTION (4.3 Å)
Cite:A highly potent extended half-life antibody as a potential RSV vaccine surrogate for all infants.
Sci Transl Med, 9, 2017
5UDE
  • Download 5ude
  • View 5ude
Molmil generated image of 5ude
CRYSTAL STRUCTURE OF RSV F B9320 DS-CAV1
Descriptor:Fusion glycoprotein F0, SULFATE ION
Authors:McLellan, J.S.
Deposit date:2016-12-26
Release date:2017-05-17
Method:X-RAY DIFFRACTION (3.001 Å)
Cite:A highly potent extended half-life antibody as a potential RSV vaccine surrogate for all infants.
Sci Transl Med, 9, 2017
5W9H
  • Download 5w9h
  • View 5w9h
Molmil generated image of 5w9h
MERS S ECTODOMAIN TRIMER IN COMPLEX WITH VARIABLE DOMAIN OF NEUTRALIZING ANTIBODY G4
Descriptor:MERS S, G4 VH, G4 VL, ...
Authors:Pallesen, J., Ward, A.B.
Deposit date:2017-06-23
Release date:2017-08-16
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W9I
  • Download 5w9i
  • View 5w9i
Molmil generated image of 5w9i
MERS S ECTODOMAIN TRIMER IN COMPLEX WITH VARIABLE DOMAIN OF NEUTRALIZING ANTIBODY G4
Descriptor:Spike glycoprotein, G4 VH, G4 VL, ...
Authors:Pallesen, J., Ward, A.B.
Deposit date:2017-06-23
Release date:2017-08-16
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W9J
  • Download 5w9j
  • View 5w9j
Molmil generated image of 5w9j
MERS S ECTODOMAIN TRIMER IN COMPLEX WITH VARIABLE DOMAIN OF NEUTRALIZING ANTIBODY G4
Descriptor:Spike glycoprotein, G4 VH, G4 VL
Authors:Pallesen, J., Ward, A.B.
Deposit date:2017-06-23
Release date:2017-08-16
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W9K
  • Download 5w9k
  • View 5w9k
Molmil generated image of 5w9k
MERS S ECTODOMAIN TRIMER IN COMPLEX WITH VARIABLE DOMAIN OF NEUTRALIZING ANTIBODY G4
Descriptor:Spike glycoprotein, G4 VH, G4 VL
Authors:Pallesen, J., Ward, A.B.
Deposit date:2017-06-23
Release date:2017-08-16
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W9L
  • Download 5w9l
  • View 5w9l
Molmil generated image of 5w9l
MERS S ECTODOMAIN TRIMER IN COMPLEX WITH VARIABLE DOMAIN OF NEUTRALIZING ANTIBODY G4
Descriptor:Spike glycoprotein, G4 VH, G4 VL
Authors:Pallesen, J., Ward, A.B.
Deposit date:2017-06-23
Release date:2017-08-16
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W9M
  • Download 5w9m
  • View 5w9m
Molmil generated image of 5w9m
MERS S ECTODOMAIN TRIMER IN COMPLEX WITH VARIABLE DOMAIN OF NEUTRALIZING ANTIBODY G4
Descriptor:Spike glycoprotein, G4 VH, G4 VL
Authors:Pallesen, J., Ward, A.B.
Deposit date:2017-06-23
Release date:2017-08-16
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W9N
  • Download 5w9n
  • View 5w9n
Molmil generated image of 5w9n
MERS S ECTODOMAIN TRIMER IN COMPLEX WITH VARIABLE DOMAIN OF NEUTRALIZING ANTIBODY G4
Descriptor:MERS S, G4 VH, G4 VL
Authors:Pallesen, J., Ward, A.B.
Deposit date:2017-06-23
Release date:2017-08-16
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (5 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
<12>
167327
PDB entries from 2020-08-05