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9NW7

CA117v2v8 Fab bound to HLA-E-VL9

Summary for 9NW7
Entry DOI10.2210/pdb9nw7/pdb
DescriptorHLA class I histocompatibility antigen, alpha chain E, Beta-2-microglobulin, CA117v2v8 heavy chain, ... (6 entities in total)
Functional Keywordshla-e, antibody, nkg2a, cd94, vl9, immune system
Biological sourceHomo sapiens (human)
More
Total number of polymer chains5
Total formula weight92530.93
Authors
Wrapp, D.,Hwang, J.K.,Marston, D.J.,Haynes, B.F.,Azoitei, M.L. (deposition date: 2025-03-21, release date: 2026-03-25)
Primary citationHwang, J.K.,Marston, D.J.,Tuyishime, M.,Yang, H.,Wrapp, D.,Li, D.,Brackenridge, S.,Frazier, M.,Rhodes, B.,Harris, C.,Quastel, M.,Kapingidza, A.B.,Gater, J.,Borrow, P.,Gillespie, G.M.,Ferrari, G.,McMichael, A.J.,Haynes, B.F.,Azoitei, M.L.
HLA-E-VL9 antibodies mediate NKG2A+ NK cell and CD8+ T cell killing of HIV-infected CD4+ T cells
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.1 Å)
Structure validation

251422

PDB entries from 2026-04-01

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