Author results

6MH8
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HIGH-VISCOSITY INJECTOR-BASED PINK BEAM SERIAL CRYSTALLOGRAPHY OF MICRO-CRYSTALS AT A SYNCHROTRON RADIATION SOURCE
Descriptor:Adenosine receptor A2a, Soluble cytochrome b562 chimeric construct, 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol
Authors:Martin-Garcia, J.M., Zhu, L., Mendez, D., Lee, M., Chun, E., Li, C., Hu, H., Subramanian, G., Kissick, D., Ogata, C., Henning, R., Ishchenko, A., Dobson, Z., Zhan, S., Weierstall, U., Spence, J.C.H., Fromme, P., Zatsepin, N.A., Fischetti, R.F., Cherezov, V., Liu, W.
Deposit date:2018-09-17
Release date:2019-04-24
Last modified:2019-05-29
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:High-viscosity injector-based pink-beam serial crystallography of microcrystals at a synchrotron radiation source.
Iucrj, 6, 2019
6MH6
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HIGH-VISCOSITY INJECTOR-BASED PINK BEAM SERIAL CRYSTALLOGRAPHY OF MICRO-CRYSTALS AT A SYNCHROTRON RADIATION SOURCE.
Descriptor:Proteinase K, CALCIUM ION, NITRATE ION
Authors:Martin-Garcia, J.M., Zhu, L., Mendez, D., Lee, M., Chun, E., Li, C., Hu, H., Subramanian, G., Kissick, D., Ogata, C., Henning, R., Ishchenko, A., Dobson, Z., Zhan, S., Weierstall, U., Spence, J.C.H., Fromme, P., Zatsepin, N.A., Fischetti, R.F., Cherezov, V., Liu, W.
Deposit date:2018-09-17
Release date:2019-04-24
Last modified:2019-05-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:High-viscosity injector-based pink-beam serial crystallography of microcrystals at a synchrotron radiation source.
Iucrj, 6, 2019
6ME9
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XFEL CRYSTAL STRUCTURE OF HUMAN MELATONIN RECEPTOR MT2 IN COMPLEX WITH RAMELTEON
Descriptor:Soluble cytochrome b562,Melatonin receptor type 1B,Rubredoxin, N-{2-[(8S)-1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan-8-yl]ethyl}propanamide, ZINC ION
Authors:Johansson, L.C., Stauch, B., McCorvy, J., Han, G.W., Patel, N., Batyuk, A., Gati, C., Li, C., Grandner, J., Hao, S., Olsen, R.H.J., Tribo, A.R., Zaare, S., Zhu, L., Zatsepin, N.A., Weierstall, U., Liu, W., Roth, B.L., Katritch, V., Cherezov, V.
Deposit date:2018-09-05
Release date:2019-04-24
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:XFEL structures of the human MT2melatonin receptor reveal the basis of subtype selectivity.
Nature, 569, 2019
6ME8
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XFEL CRYSTAL STRUCTURE OF HUMAN MELATONIN RECEPTOR MT2 (N86D) IN COMPLEX WITH 2-PHENYLMELATONIN
Descriptor:Soluble cytochrome b562,Melatonin receptor type 1B,Rubredoxin, N-[2-(5-methoxy-2-phenyl-1H-indol-3-yl)ethyl]acetamide, ZINC ION
Authors:Johansson, L.C., Stauch, B., McCorvy, J., Han, G.W., Patel, N., Batyuk, A., Gati, C., Li, C., Grandner, J., Hao, S., Olsen, R.H.J., Tribo, A.R., Zaare, S., Zhu, L., Zatsepin, N.A., Weierstall, U., Liu, W., Roth, B.L., Katritch, V., Cherezov, V.
Deposit date:2018-09-05
Release date:2019-04-24
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:XFEL structures of the human MT2melatonin receptor reveal the basis of subtype selectivity.
Nature, 569, 2019
6ME7
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XFEL CRYSTAL STRUCTURE OF HUMAN MELATONIN RECEPTOR MT2 (H208A) IN COMPLEX WITH 2-PHENYLMELATONIN
Descriptor:Soluble cytochrome b562,Melatonin receptor type 1B,Rubredoxin, N-[2-(5-methoxy-2-phenyl-1H-indol-3-yl)ethyl]acetamide, ZINC ION, ...
Authors:Johansson, L.C., Stauch, B., McCorvy, J., Han, G.W., Patel, N., Batyuk, A., Gati, C., Li, C., Grandner, J., Hao, S., Olsen, R.H.J., Tribo, A.R., Zaare, S., Zhu, L., Zatsepin, N.A., Weierstall, U., Liu, W., Roth, B.L., Katritch, V., Cherezov, V.
Deposit date:2018-09-05
Release date:2019-04-24
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:XFEL structures of the human MT2melatonin receptor reveal the basis of subtype selectivity.
Nature, 569, 2019
6ME6
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XFEL CRYSTAL STRUCTURE OF HUMAN MELATONIN RECEPTOR MT2 IN COMPLEX WITH 2-PHENYLMELATONIN
Descriptor:Soluble cytochrome b562,Melatonin receptor type 1B,Rubredoxin, N-[2-(5-methoxy-2-phenyl-1H-indol-3-yl)ethyl]acetamide, ZINC ION, ...
Authors:Johansson, L.C., Stauch, B., McCorvy, J., Han, G.W., Patel, N., Batyuk, A., Gati, C., Li, C., Grandner, J., Hao, S., Olsen, R.H.J., Tribo, A.R., Zaare, S., Zhu, L., Zatsepin, N.A., Weierstall, U., Liu, W., Roth, B.L., Katritch, V., Cherezov, V.
Deposit date:2018-09-05
Release date:2019-04-24
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:XFEL structures of the human MT2melatonin receptor reveal the basis of subtype selectivity.
Nature, 569, 2019
6ME5
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XFEL CRYSTAL STRUCTURE OF HUMAN MELATONIN RECEPTOR MT1 IN COMPLEX WITH AGOMELATINE
Descriptor:chimera protein of Melatonin receptor type 1A and GlgA glycogen synthase, ~{N}-[2-(7-methoxynaphthalen-1-yl)ethyl]ethanamide, OLEIC ACID
Authors:Stauch, B., Johansson, L.C., McCorvy, J.D., Patel, N., Han, G.W., Gati, C., Batyuk, A., Ishchenko, A., Brehm, W., White, T.A., Michaelian, N., Madsen, C., Zhu, L., Grant, T.D., Grandner, J.M., Olsen, R.H.J., Tribo, A.R., Weierstall, U., Roth, B.L., Katritch, V., Liu, W., Cherezov, V.
Deposit date:2018-09-05
Release date:2019-04-24
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis of ligand recognition at the human MT1melatonin receptor.
Nature, 569, 2019
6ME4
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XFEL CRYSTAL STRUCTURE OF HUMAN MELATONIN RECEPTOR MT1 IN COMPLEX WITH 2-IODOMELATONIN
Descriptor:chimera protein of Melatonin receptor type 1A and GlgA glycogen synthase, N-[2-(2-iodo-5-methoxy-1H-indol-3-yl)ethyl]acetamide, DI(HYDROXYETHYL)ETHER, ...
Authors:Stauch, B., Johansson, L.C., McCorvy, J.D., Patel, N., Han, G.W., Gati, C., Batyuk, A., Ishchenko, A., Brehm, W., White, T.A., Michaelian, N., Madsen, C., Zhu, L., Grant, T.D., Grandner, J.M., Olsen, R.H.J., Tribo, A.R., Weierstall, U., Roth, B.L., Katritch, V., Liu, W., Cherezov, V.
Deposit date:2018-09-05
Release date:2019-04-24
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis of ligand recognition at the human MT1melatonin receptor.
Nature, 569, 2019
6ME3
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XFEL CRYSTAL STRUCTURE OF HUMAN MELATONIN RECEPTOR MT1 IN COMPLEX WITH 2-PHENYLMELATONIN
Descriptor:chimera protein of Melatonin receptor type 1A and GlgA glycogen synthase, N-[2-(5-methoxy-2-phenyl-1H-indol-3-yl)ethyl]acetamide, OLEIC ACID, ...
Authors:Stauch, B., Johansson, L.C., McCorvy, J.D., Patel, N., Han, G.W., Gati, C., Batyuk, A., Ishchenko, A., Brehm, W., White, T.A., Michaelian, N., Madsen, C., Zhu, L., Grant, T.D., Grandner, J.M., Olsen, R.H.J., Tribo, A.R., Weierstall, U., Roth, B.L., Katritch, V., Liu, W., Cherezov, V.
Deposit date:2018-09-05
Release date:2019-04-24
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis of ligand recognition at the human MT1melatonin receptor.
Nature, 569, 2019
6ME2
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XFEL CRYSTAL STRUCTURE OF HUMAN MELATONIN RECEPTOR MT1 IN COMPLEX WITH RAMELTEON
Descriptor:chimera protein of Melatonin receptor type 1A and GlgA glycogen synthase, N-{2-[(8S)-1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan-8-yl]ethyl}propanamide, OLEIC ACID, ...
Authors:Stauch, B., Johansson, L.C., McCorvy, J.D., Patel, N., Han, G.W., Gati, C., Batyuk, A., Ishchenko, A., Brehm, W., White, T.A., Michaelian, N., Madsen, C., Zhu, L., Grant, T.D., Grandner, J.M., Olsen, R.H.J., Tribo, A.R., Weierstall, U., Roth, B.L., Katritch, V., Liu, W., Cherezov, V.
Deposit date:2018-09-05
Release date:2019-04-24
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis of ligand recognition at the human MT1melatonin receptor.
Nature, 569, 2019
6M9T
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CRYSTAL STRUCTURE OF EP3 RECEPTOR BOUND TO MISOPROSTOL-FA
Descriptor:Prostaglandin E2 receptor EP3 subtype, Endolysin chimera, (11alpha,12alpha,13E,16S)-11,16-dihydroxy-16-methyl-9-oxoprost-13-en-1-oic acid, ...
Authors:Audet, M., White, K.L., Breton, B., Zarzycka, B., Han, G.W., Lu, Y., Gati, C., Batyuk, A., Popov, P., Velasquez, J., Manahan, D., Hu, H., Weierstall, U., Liu, W., Shui, W., Katrich, V., Cherezov, V., Hanson, M.A., Stevens, R.C.
Deposit date:2018-08-24
Release date:2018-12-05
Last modified:2019-02-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of misoprostol bound to the labor inducer prostaglandin E2receptor.
Nat. Chem. Biol., 15, 2019
6G7L
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RETINAL ISOMERIZATION IN BACTERIORHODOPSIN REVEALED BY A FEMTOSECOND X-RAY LASER: 8.3 MS STATE STRUCTURE
Descriptor:Bacteriorhodopsin, RETINAL, 1-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL, ...
Authors:Nogly, P., Weinert, T., James, D., Cabajo, S., Ozerov, D., Furrer, A., Gashi, D., Borin, V., Skopintsev, P., Jaeger, K., Nass, K., Bath, P., Bosman, R., Koglin, J., Seaberg, M., Lane, T., Kekilli, D., Bruenle, S., Tanaka, T., Wu, W., Milne, C., White, T., Barty, A., Weierstall, U., Panneels, V., Nango, E., Iwata, S., Hunter, M., Schapiro, I., Schertler, G., Neutze, R., Standfuss, J.
Deposit date:2018-04-06
Release date:2018-06-27
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Retinal isomerization in bacteriorhodopsin captured by a femtosecond x-ray laser.
Science, 361, 2018
6G7K
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RETINAL ISOMERIZATION IN BACTERIORHODOPSIN REVEALED BY A FEMTOSECOND X-RAY LASER: 10 PS STATE STRUCTURE
Descriptor:Bacteriorhodopsin, RETINAL, 1-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL, ...
Authors:Nogly, P., Weinert, T., James, D., Cabajo, S., Ozerov, D., Furrer, A., Gashi, D., Borin, V., Skopintsev, P., Jaeger, K., Nass, K., Bath, P., Bosman, R., Koglin, J., Seaberg, M., Lane, T., Kekilli, D., Bruenle, S., Tanaka, T., Wu, W., Milne, C., White, T., Barty, A., Weierstall, U., Panneels, V., Nango, E., Iwata, S., Hunter, M., Schapiro, I., Schertler, G., Neutze, R., Standfuss, J.
Deposit date:2018-04-06
Release date:2018-06-27
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Retinal isomerization in bacteriorhodopsin captured by a femtosecond x-ray laser.
Science, 361, 2018
6G7J
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RETINAL ISOMERIZATION IN BACTERIORHODOPSIN REVEALED BY A FEMTOSECOND X-RAY LASER: 457-646 FS STATE STRUCTURE
Descriptor:Bacteriorhodopsin, RETINAL, 1-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL, ...
Authors:Nogly, P., Weinert, T., James, D., Cabajo, S., Ozerov, D., Furrer, A., Gashi, D., Borin, V., Skopintsev, P., Jaeger, K., Nass, K., Bath, P., Bosman, R., Koglin, J., Seaberg, M., Lane, T., Kekilli, D., Bruenle, S., Tanaka, T., Wu, W., Milne, C., White, T., Barty, A., Weierstall, U., Panneels, V., Nango, E., Iwata, S., Hunter, M., Schapiro, I., Schertler, G., Neutze, R., Standfuss, J.
Deposit date:2018-04-06
Release date:2018-06-27
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Retinal isomerization in bacteriorhodopsin captured by a femtosecond x-ray laser.
Science, 361, 2018
6G7I
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RETINAL ISOMERIZATION IN BACTERIORHODOPSIN REVEALED BY A FEMTOSECOND X-RAY LASER: 49-406 FS STATE STRUCTURE
Descriptor:Bacteriorhodopsin, RETINAL, 1-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL, ...
Authors:Nogly, P., Weinert, T., James, D., Cabajo, S., Ozerov, D., Furrer, A., Gashi, D., Borin, V., Skopintsev, P., Jaeger, K., Nass, K., Bath, P., Bosman, R., Koglin, J., Seaberg, M., Lane, T., Kekilli, D., Bruenle, S., Tanaka, T., Wu, W., Milne, C., White, T., Barty, A., Weierstall, U., Panneels, V., Nango, E., Iwata, S., Hunter, M., Schapiro, I., Schertler, G., Neutze, R., Standfuss, J.
Deposit date:2018-04-06
Release date:2018-06-27
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Retinal isomerization in bacteriorhodopsin captured by a femtosecond x-ray laser.
Science, 361, 2018
6G7H
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RETINAL ISOMERIZATION IN BACTERIORHODOPSIN REVEALED BY A FEMTOSECOND X-RAY LASER: RESTING STATE STRUCTURE
Descriptor:Bacteriorhodopsin, RETINAL, 1-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL, ...
Authors:Nogly, P., Weinert, T., James, D., Cabajo, S., Ozerov, D., Furrer, A., Gashi, D., Borin, V., Skopintsev, P., Jaeger, K., Nass, K., Bath, P., Bosman, R., Koglin, J., Seaberg, M., Lane, T., Kekilli, D., Bruenle, S., Tanaka, T., Wu, W., Milne, C., White, T., Barty, A., Weierstall, U., Panneels, V., Nango, E., Iwata, S., Hunter, M., Schapiro, I., Schertler, G., Neutze, R., Standfuss, J.
Deposit date:2018-04-06
Release date:2018-06-27
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Retinal isomerization in bacteriorhodopsin captured by a femtosecond x-ray laser.
Science, 361, 2018
6B6F
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BETA-LACTAMASE, MIXED WITH CEFTRIAXONE, NEEDLES CRYSTAL FORM, 2SEC
Descriptor:Beta-lactamase, Ceftriaxone
Authors:Pandey, S., Schmidt, M.
Deposit date:2017-10-01
Release date:2018-06-27
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Enzyme intermediates captured "on the fly" by mix-and-inject serial crystallography.
BMC Biol., 16, 2018
6B6E
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BETA-LACTAMASE, MIXED WITH CEFTRIAXONE, NEEDLES CRYSTAL FORM, 500MS
Descriptor:Beta-lactamase, (2R)-2-[(1S)-1-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-2-hydroxyethyl]-5-methylidene-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, Ceftriaxone
Authors:Pandey, S., Schmidt, M.
Deposit date:2017-10-01
Release date:2018-06-27
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:Enzyme intermediates captured "on the fly" by mix-and-inject serial crystallography.
BMC Biol., 16, 2018
6B6D
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BETA-LACTAMASE, MIXED WITH CEFTRIAXONE, NEEDLES CRYSTAL FORM, 100MS
Descriptor:Beta-lactamase, (2R)-2-[(1S)-1-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-2-hydroxyethyl]-5-methylidene-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, Ceftriaxone
Authors:Pandey, S., Schmidt, M.
Deposit date:2017-10-01
Release date:2018-06-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Enzyme intermediates captured "on the fly" by mix-and-inject serial crystallography.
BMC Biol., 16, 2018
6B6C
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BETA-LACTAMASE, MIXED WITH CEFTRIAXONE, NEEDLES CRYSTAL FORM, 30MS
Descriptor:Beta-lactamase, Ceftriaxone
Authors:Pandey, S., Schmidt, M.
Deposit date:2017-10-01
Release date:2018-06-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Enzyme intermediates captured "on the fly" by mix-and-inject serial crystallography.
BMC Biol., 16, 2018
6B6B
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BETA-LACTAMASE, UNMIXED NEEDLES CRYSTAL FORM
Descriptor:Beta-lactamase
Authors:Pandey, S., Schmidt, M.
Deposit date:2017-10-01
Release date:2018-06-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Enzyme intermediates captured "on the fly" by mix-and-inject serial crystallography.
BMC Biol., 16, 2018
6B6A
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BETA-LACTAMASE, 2SECS TIMEPOINT, MIXED, SHARDS CRYSTAL FORM
Descriptor:Beta-lactamase, PHOSPHATE ION, Ceftriaxone, ...
Authors:Pandey, S., Schmidt, M.
Deposit date:2017-10-01
Release date:2018-06-27
Method:X-RAY DIFFRACTION (2.298 Å)
Cite:Enzyme intermediates captured "on the fly" by mix-and-inject serial crystallography.
BMC Biol., 16, 2018
6B69
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BETA-LACTAMASE, 500MS TIMEPOINT, MIXED, SHARDS CRYSTAL FORM
Descriptor:Beta-lactamase, PHOSPHATE ION, Ceftriaxone, ...
Authors:Pandey, S., Schmidt, M.
Deposit date:2017-10-01
Release date:2018-06-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Enzyme intermediates captured "on the fly" by mix-and-inject serial crystallography.
BMC Biol., 16, 2018
6B68
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BETA-LACTAMASE, 100MS TIMEPOINT, MIXED, SHARDS CRYSTAL FORM
Descriptor:Beta-lactamase, PHOSPHATE ION, Ceftriaxone, ...
Authors:Pandey, S., Schmidt, M.
Deposit date:2017-10-01
Release date:2018-06-27
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Enzyme intermediates captured "on the fly" by mix-and-inject serial crystallography.
BMC Biol., 16, 2018
6B5Y
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BETA-LACTAMASE, MIXED WITH CEFTRIAXONE, 30MS TIME POINT, SHARDS CRYSTAL FORM
Descriptor:Beta-lactamase, PHOSPHATE ION, Ceftriaxone
Authors:Pandey, S., Schmidt, M.
Deposit date:2017-09-29
Release date:2018-06-27
Last modified:2019-04-17
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Enzyme intermediates captured "on the fly" by mix-and-inject serial crystallography.
BMC Biol., 16, 2018