Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

6PS1

XFEL beta2 AR structure by ligand exchange from Alprenolol to Timolol.

Summary for 6PS1
Entry DOI10.2210/pdb6ps1/pdb
DescriptorFusion protein of Beta-2 adrenergic receptor and T4 lysozyme, (2S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol, SULFATE ION, ... (6 entities in total)
Functional Keywordsgpcr, complex-lcp method, sbdd, drug design, xfel, lcp-sfx, ligand exchange, alprenolol, timolol, b2ar, beta2ar, membrane protein
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains1
Total formula weight59761.05
Authors
Primary citationIshchenko, A.,Stauch, B.,Han, G.W.,Batyuk, A.,Shiriaeva, A.,Li, C.,Zatsepin, N.,Weierstall, U.,Liu, W.,Nango, E.,Nakane, T.,Tanaka, R.,Tono, K.,Joti, Y.,Iwata, S.,Moraes, I.,Gati, C.,Cherezov, V.
Toward G protein-coupled receptor structure-based drug design using X-ray lasers.
Iucrj, 6:1106-1119, 2019
Cited by
PubMed: 31709066
DOI: 10.1107/S2052252519013137
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.2 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon