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5SVJ
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CRYSTAL STRUCTURE OF THE ATP-GATED HUMAN P2X3 ION CHANNEL IN THE CLOSED, APO STATE
Descriptor:P2X purinoceptor 3, N-ACETYL-D-GLUCOSAMINE, MAGNESIUM ION, ...
Authors:Mansoor, S.E., Lu, W., Oosterheert, W., Shekhar, M., Tajkhorshid, E., Gouaux, E.
Deposit date:2016-08-06
Release date:2016-09-28
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.984 Å)
Cite:X-ray structures define human P2X3 receptor gating cycle and antagonist action.
Nature, 538, 2016
5SVK
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CRYSTAL STRUCTURE OF THE ATP-GATED HUMAN P2X3 ION CHANNEL IN THE ATP-BOUND, OPEN STATE
Descriptor:P2X purinoceptor 3, ADENOSINE-5'-TRIPHOSPHATE, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Mansoor, S.E., Lu, W., Oosterheert, W., Shekhar, M., Tajkhorshid, E., Gouaux, E.
Deposit date:2016-08-06
Release date:2016-09-28
Last modified:2016-10-19
Method:X-RAY DIFFRACTION (2.773 Å)
Cite:X-ray structures define human P2X3 receptor gating cycle and antagonist action.
Nature, 538, 2016
5SVL
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CRYSTAL STRUCTURE OF THE ATP-GATED HUMAN P2X3 ION CHANNEL IN THE ATP-BOUND, CLOSED (DESENSITIZED) STATE
Descriptor:P2X purinoceptor 3, ADENOSINE-5'-TRIPHOSPHATE, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Mansoor, S.E., Lu, W., Oosterheert, W., Shekhar, M., Tajkhorshid, E., Gouaux, E.
Deposit date:2016-08-06
Release date:2016-10-05
Last modified:2016-10-19
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:X-ray structures define human P2X3 receptor gating cycle and antagonist action.
Nature, 538, 2016
5SVM
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CRYSTAL STRUCTURE OF THE ATP-GATED HUMAN P2X3 ION CHANNEL BOUND TO AGONIST 2-METHYLTHIO-ATP IN THE DESENSITIZED STATE
Descriptor:P2X purinoceptor 3, N-ACETYL-D-GLUCOSAMINE, 2-(methylsulfanyl)adenosine 5'-(tetrahydrogen triphosphate), ...
Authors:Mansoor, S.E., Lu, W., Oosterheert, W., Shekhar, M., Tajkhorshid, E., Gouaux, E.
Deposit date:2016-08-06
Release date:2016-09-28
Last modified:2016-10-19
Method:X-RAY DIFFRACTION (3.093 Å)
Cite:X-ray structures define human P2X3 receptor gating cycle and antagonist action.
Nature, 538, 2016
5SVP
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ANOMALOUS SULFUR SIGNAL REVEALS THE POSITION OF AGONIST 2-METHYLTHIO-ATP BOUND TO THE ATP-GATED HUMAN P2X3 ION CHANNEL IN THE DESENSITIZED STATE
Descriptor:P2X purinoceptor 3, N-ACETYL-D-GLUCOSAMINE, 2-(methylsulfanyl)adenosine 5'-(tetrahydrogen triphosphate), ...
Authors:Mansoor, S.E., Lu, W., Oosterheert, W., Shekhar, M., Tajkhorshid, E., Gouaux, E.
Deposit date:2016-08-07
Release date:2016-09-28
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (3.298 Å)
Cite:X-ray structures define human P2X3 receptor gating cycle and antagonist action.
Nature, 538, 2016
5SVQ
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CRYSTAL STRUCTURE OF THE ATP-GATED HUMAN P2X3 ION CHANNEL BOUND TO COMPETITIVE ANTAGONIST TNP-ATP
Descriptor:P2X purinoceptor 3, N-ACETYL-D-GLUCOSAMINE, SODIUM ION, ...
Authors:Mansoor, S.E., Lu, W., Oosterheert, W., Shekhar, M., Tajkhorshid, E., Gouaux, E.
Deposit date:2016-08-07
Release date:2016-10-05
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:X-ray structures define human P2X3 receptor gating cycle and antagonist action.
Nature, 538, 2016
5SVR
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CRYSTAL STRUCTURE OF THE ATP-GATED HUMAN P2X3 ION CHANNEL BOUND TO COMPETITIVE ANTAGONIST A-317491
Descriptor:P2X purinoceptor 3, N-ACETYL-D-GLUCOSAMINE, MAGNESIUM ION, ...
Authors:Mansoor, S.E., Lu, W., Oosterheert, W., Shekhar, M., Tajkhorshid, E., Gouaux, E.
Deposit date:2016-08-07
Release date:2016-10-05
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (3.13 Å)
Cite:X-ray structures define human P2X3 receptor gating cycle and antagonist action.
Nature, 538, 2016
5SVS
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ANOMALOUS MN2+ SIGNAL REVEALS A DIVALENT CATION-BINDING SITE IN THE HEAD DOMAIN OF THE ATP-GATED HUMAN P2X3 ION CHANNEL
Descriptor:P2X purinoceptor 3, N-ACETYL-D-GLUCOSAMINE, MAGNESIUM ION, ...
Authors:Mansoor, S.E., Lu, W., Oosterheert, W., Shekhar, M., Tajkhorshid, E., Gouaux, E.
Deposit date:2016-08-07
Release date:2016-09-28
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (4.025 Å)
Cite:X-ray structures define human P2X3 receptor gating cycle and antagonist action.
Nature, 538, 2016
5SVT
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ANOMALOUS CS+ SIGNAL REVEALS THE SITE OF NA+ ION ENTRY TO THE CHANNEL PORE OF THE HUMAN P2X3 ION CHANNEL THROUGH THE EXTRACELLULAR FENESTRATIONS
Descriptor:P2X purinoceptor 3, N-ACETYL-D-GLUCOSAMINE, MAGNESIUM ION, ...
Authors:Mansoor, S.E., Lu, W., Oosterheert, W., Shekhar, M., Tajkhorshid, E., Gouaux, E.
Deposit date:2016-08-07
Release date:2016-09-28
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (3.794 Å)
Cite:X-ray structures define human P2X3 receptor gating cycle and antagonist action.
Nature, 538, 2016
5VOT
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STRUCTURE OF A PROTEIN COMPLEX
Descriptor:Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit
Authors:Chen, S., Zhao, Y., Wang, Y.S., Shekhar, M., Tajkhorshid, E., Gouaux, E.
Deposit date:2017-05-03
Release date:2017-07-12
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:Activation and Desensitization Mechanism of AMPA Receptor-TARP Complex by Cryo-EM.
Cell, 170, 2017
5VOU
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STRUCTURE OF A PROTEIN COMPLEX
Descriptor:Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit
Authors:Chen, S., Zhao, Y., Wang, Y.S., Shekhar, M., Tajkhorshid, E., Gouaux, E.
Deposit date:2017-05-03
Release date:2017-07-12
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (6.4 Å)
Cite:Activation and Desensitization Mechanism of AMPA Receptor-TARP Complex by Cryo-EM.
Cell, 170, 2017
5VOV
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STRUCTURE OF A PROTEIN COMPLEX
Descriptor:Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit
Authors:Zhao, Y., Chen, S., Wang, Y.S., Shekhar, M., Tajkhorshid, E., Gouaux, E.
Deposit date:2017-05-03
Release date:2017-07-12
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (7.7 Å)
Cite:Activation and Desensitization Mechanism of AMPA Receptor-TARP Complex by Cryo-EM.
Cell, 170, 2017
2B5F
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CRYSTAL STRUCTURE OF THE SPINACH AQUAPORIN SOPIP2;1 IN AN OPEN CONFORMATION TO 3.9 RESOLUTION
Descriptor:aquaporin
Authors:Tornroth-Horsefield, S., Wang, Y., Hedfalk, K., Johanson, U., Karlsson, M., Tajkhorshid, E., Neutze, R., Kjellbom, P.
Deposit date:2005-09-28
Release date:2005-12-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Structural mechanism of plant aquaporin gating
Nature, 439, 2006
3ZOJ
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HIGH-RESOLUTION STRUCTURE OF PICHIA PASTORIS AQUAPORIN AQY1 AT 0.88 A
Descriptor:AQUAPORIN, B-OCTYLGLUCOSIDE, CHLORIDE ION
Authors:Kosinska-Eriksson, U., Fischer, G., Friemann, R., Enkavi, G., Tajkhorshid, E., Neutze, R.
Deposit date:2013-02-21
Release date:2013-06-26
Last modified:2013-07-03
Method:X-RAY DIFFRACTION (0.88 Å)
Cite:Subangstrom Resolution X-Ray Structure Details Aquaporin-Water Interactions
Science, 340, 2013
5DX3
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ESTROGEN RECEPTOR ALPHA LIGAND BINDING DOMAIN Y537S MUTANT IN COMPLEX WITH STAPLED PEPTIDE SRC2-P3 AND ESTRADIOL
Descriptor:Estrogen receptor, Stapled Peptide SRC2-P3, ESTRADIOL, ...
Authors:Speltz, T.E., Fanning, S.W., Mayne, C.G., Tajkhorshid, E., Greene, G.L., Moore, T.W.
Deposit date:2015-09-23
Release date:2016-07-20
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.0903 Å)
Cite:Stapled Peptides with gamma-Methylated Hydrocarbon Chains for the Estrogen Receptor/Coactivator Interaction.
Angew.Chem.Int.Ed.Engl., 55, 2016
5DXB
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ESTROGEN RECEPTOR ALPHA LIGAND BINDING DOMAIN Y537S MUTANT IN COMPLEX WITH STAPLED PEPTIDE SRC2-P1 AND ESTRADIOL
Descriptor:Estrogen receptor, Nuclear receptor coactivator 2, ESTRADIOL, ...
Authors:Fanning, S.W., Speltz, T.E., Mayne, C.G., Tajkhorshid, E., Greene, G.L., Moore, T.W.
Deposit date:2015-09-23
Release date:2016-07-27
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Stapled Peptides with gamma-Methylated Hydrocarbon Chains for the Estrogen Receptor/Coactivator Interaction.
Angew. Chem. Int. Ed. Engl., 55, 2016
5DXE
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ESTROGEN RECEPTOR ALPHA LIGAND BINDING DOMAIN Y537S MUTANT IN COMPLEX WITH STAPLED PEPTIDE SRC2-P4 AND ESTRADIOL
Descriptor:Estrogen receptor, Nuclear receptor coactivator 2, ESTRADIOL
Authors:Fanning, S.W., Speltz, T.E., Mayne, C.G., Tajkhorshid, E., Greene, G.L., Moore, T.W.
Deposit date:2015-09-23
Release date:2016-08-03
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Stapled Peptides with gamma-Methylated Hydrocarbon Chains for the Estrogen Receptor/Coactivator Interaction.
Angew.Chem.Int.Ed.Engl., 55, 2016
5DXG
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ESTROGEN RECEPTOR ALPHA LIGAND BINDING DOMAIN Y537S MUTANT IN COMPLEX WITH STAPLED PEPTIDE SRC2-P5
Descriptor:Estrogen receptor, Stapled Peptide SRC2-P5, ESTRADIOL, ...
Authors:Fanning, S.W., Speltz, T.E., Mayne, C.G., Tajkhorshid, E., Greene, G.L., Moore, T.W.
Deposit date:2015-09-23
Release date:2016-07-27
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Stapled Peptides with gamma-Methylated Hydrocarbon Chains for the Estrogen Receptor/Coactivator Interaction.
Angew. Chem. Int. Ed. Engl., 55, 2016
5HYR
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ESTROGEN RECEPTOR ALPHA LIGAND BINDING DOMAIN Y537S MUTANT IN COMPLEX WITH STAPLED PEPTIDE SRC2-SP2 AND ESTRADIOL
Descriptor:Estrogen receptor, Stapled Peptide SRC2-SP2, ESTRADIOL, ...
Authors:Fanning, S.W., Speltz, T.E., Mayne, C.G., Tajkhorshid, E., Greene, G.L., Moore, T.W.
Deposit date:2016-02-01
Release date:2016-05-25
Method:X-RAY DIFFRACTION (2.271 Å)
Cite:Stapled Peptides with gamma-Methylated Hydrocarbon Chains for the Estrogen Receptor/Coactivator Interaction.
Angew.Chem.Int.Ed.Engl., 55, 2016
5U4I
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STRUCTURAL BASIS OF CO-TRANSLATIONAL QUALITY CONTROL BY ARFA AND RF2 BOUND TO RIBOSOME
Descriptor:23S rRNA, 5S rRNA, 50S ribosomal protein L2, ...
Authors:Zeng, F., Chen, Y., Remis, J., Shekhar, M., Phillips, J.C., Tajkhorshid, E., Jin, H.
Deposit date:2016-12-04
Release date:2017-01-11
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis of co-translational quality control by ArfA and RF2 bound to ribosome.
Nature, 541, 2017
5U4J
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STRUCTURAL BASIS OF CO-TRANSLATIONAL QUALITY CONTROL BY ARFA AND RF2 BOUND TO RIBOSOME
Descriptor:16S rRNA, 23S rRNA, 30S ribosomal protein S3, ...
Authors:Zeng, F., Chen, Y., Remis, J., Shekhar, M., Phillips, J.C., Tajkhorshid, E., Jin, H.
Deposit date:2016-12-04
Release date:2017-01-11
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural basis of co-translational quality control by ArfA and RF2 bound to ribosome.
Nature, 541, 2017
5WGD
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ESTROGEN RECEPTOR ALPHA LIGAND BINDING DOMAIN IN COMPLEX WITH ESTRADIOL AND SRC2-LP1
Descriptor:Estrogen receptor, (ACE)HKILHKLLQDS(NH2), (ACE)AILHKLLQDS(NH2), ...
Authors:Fanning, S.W., Speltz, T.E., Mayne, C.G., Siddiqui, Z., Greene, G.L., Tajkhorshid, E., Moore, T.W.
Deposit date:2017-07-14
Release date:2018-06-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A "cross-stitched" peptide with improved helicity and proteolytic stability.
Org. Biomol. Chem., 16, 2018
5WGQ
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ESTROGEN RECEPTOR ALPHA LIGAND BINDING DOMAIN IN COMPLEX WITH ESTRADIOL AND SRC2-BCP1
Descriptor:Estrogen receptor, SRC2-BCP1, ESTRADIOL
Authors:Fanning, S.W., Speltz, T.E., Mayne, C.G., Siddiqui, Z., Greene, G.L., Tajkhorshid, E., Moore, T.W.
Deposit date:2017-07-14
Release date:2018-06-13
Last modified:2018-07-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A "cross-stitched" peptide with improved helicity and proteolytic stability.
Org. Biomol. Chem., 16, 2018
6BTM
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STRUCTURE OF ALTERNATIVE COMPLEX III FROM FLAVOBACTERIUM JOHNSONIAE (WILD TYPE)
Descriptor:Alternative Complex III subunit A, Alternative Complex III subunit B, Alternative Complex III subunit C, ...
Authors:Sun, C., Benlekbir, S., Venkatakrishnan, P., Yuhang, W., Tajkhorshid, E., Rubinstein, J.L., Gennis, R.B.
Deposit date:2017-12-07
Release date:2018-05-09
Last modified:2018-05-16
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure of the alternative complex III in a supercomplex with cytochrome oxidase.
Nature, 557, 2018
1LDA
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CRYSTAL STRUCTURE OF THE E. COLI GLYCEROL FACILITATOR (GLPF) WITHOUT SUBSTRATE GLYCEROL
Descriptor:Glycerol uptake facilitator protein, B-OCTYLGLUCOSIDE
Authors:Nollert, P., Miercke, L.J.W., O'Connell, J., Stroud, R.M.
Deposit date:2002-04-08
Release date:2002-05-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Control of the selectivity of the aquaporin water channel family by global orientational tuning.
Science, 296, 2002
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