5WGQ
Estrogen Receptor Alpha Ligand Binding Domain in Complex with Estradiol and SRC2-BCP1
Summary for 5WGQ
Entry DOI | 10.2210/pdb5wgq/pdb |
Related PRD ID | PRD_002318 |
Descriptor | Estrogen receptor, SRC2-BCP1, ESTRADIOL, ... (4 entities in total) |
Functional Keywords | breast cancer, stapled peptides, synthetic peptides, hormone., transcription, transcription-transcription inhibitor complex, transcription/transcription inhibitor |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 62868.39 |
Authors | Fanning, S.W.,Speltz, T.E.,Mayne, C.G.,Siddiqui, Z.,Greene, G.L.,Tajkhorshid, E.,Moore, T.W. (deposition date: 2017-07-14, release date: 2018-06-13, Last modification date: 2023-11-15) |
Primary citation | Speltz, T.E.,Mayne, C.G.,Fanning, S.W.,Siddiqui, Z.,Tajkhorshid, E.,Greene, G.L.,Moore, T.W. A "cross-stitched" peptide with improved helicity and proteolytic stability. Org. Biomol. Chem., 16:3702-3706, 2018 Cited by PubMed: 29725689DOI: 10.1039/c8ob00790j PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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