8BHT

ABCG2 turnover-1 state with tariquidar bound

Summary for 8BHT

Entry DOI	10.2210/pdb8bht/pdb
Related	8BI0
EMDB information	16069
Descriptor	Broad substrate specificity ATP-binding cassette transporter ABCG2, ADENOSINE-5'-TRIPHOSPHATE, CHOLESTEROL, ... (4 entities in total)
Functional Keywords	multidrug resistance, abc transporter, transport protein
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	149488.28
Authors	Yu, Q.,Kowal, J.,Tajkhorshid, E.,Locher, K.P. (deposition date: 2022-10-31, release date: 2023-01-11)
Primary citation	Rasouli, A.,Yu, Q.,Dehghani-Ghahnaviyeh, S.,Wen, P.C.,Kowal, J.,Locher, K.P.,Tajkhorshid, E. Differential dynamics and direct interaction of bound ligands with lipids in multidrug transporter ABCG2. Proc.Natl.Acad.Sci.USA, 120:e2213437120-e2213437120, 2023 Cited by PubMed: 36580587 DOI: 10.1073/pnas.2213437120 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.1 Å)

Structure validation