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5WGD

Estrogen Receptor Alpha Ligand Binding Domain in Complex with Estradiol and SRC2-LP1

Summary for 5WGD
Entry DOI10.2210/pdb5wgd/pdb
DescriptorEstrogen receptor, (ACE)HKILHKLLQDS(NH2), (ACE)AILHKLLQDS(NH2), ... (5 entities in total)
Functional Keywordsbreast cancer, stapled peptides, synthetic peptides, hormone, transcription
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains4
Total formula weight62616.04
Authors
Fanning, S.W.,Speltz, T.E.,Mayne, C.G.,Siddiqui, Z.,Greene, G.L.,Tajkhorshid, E.,Moore, T.W. (deposition date: 2017-07-14, release date: 2018-06-13, Last modification date: 2023-10-04)
Primary citationSpeltz, T.E.,Mayne, C.G.,Fanning, S.W.,Siddiqui, Z.,Tajkhorshid, E.,Greene, G.L.,Moore, T.W.
A "cross-stitched" peptide with improved helicity and proteolytic stability.
Org. Biomol. Chem., 16:3702-3706, 2018
Cited by
PubMed: 29725689
DOI: 10.1039/c8ob00790j
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

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