8BI0

ABCG2 turnover-2 state with tariquidar bound

Summary for 8BI0

Entry DOI	10.2210/pdb8bi0/pdb
Related	8BHT
EMDB information	16069 16075
Descriptor	Broad substrate specificity ATP-binding cassette transporter ABCG2, ADENOSINE-5'-TRIPHOSPHATE, CHOLESTEROL, ... (6 entities in total)
Functional Keywords	multidrug resistance, abc transporter, transport protein
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	151555.86
Authors	Yu, Q.,Kowal, J.,Tajkhorshid, E.,Locher, K.P. (deposition date: 2022-11-01, release date: 2023-01-11)
Primary citation	Rasouli, A.,Yu, Q.,Dehghani-Ghahnaviyeh, S.,Wen, P.C.,Kowal, J.,Locher, K.P.,Tajkhorshid, E. Differential dynamics and direct interaction of bound ligands with lipids in multidrug transporter ABCG2. Proc.Natl.Acad.Sci.USA, 120:e2213437120-e2213437120, 2023 Cited by PubMed: 36580587 DOI: 10.1073/pnas.2213437120 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.2 Å)

Structure validation