8BI0
ABCG2 turnover-2 state with tariquidar bound
Summary for 8BI0
Entry DOI | 10.2210/pdb8bi0/pdb |
Related | 8BHT |
EMDB information | 16069 16075 |
Descriptor | Broad substrate specificity ATP-binding cassette transporter ABCG2, ADENOSINE-5'-TRIPHOSPHATE, CHOLESTEROL, ... (6 entities in total) |
Functional Keywords | multidrug resistance, abc transporter, transport protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 151555.86 |
Authors | Yu, Q.,Kowal, J.,Tajkhorshid, E.,Locher, K.P. (deposition date: 2022-11-01, release date: 2023-01-11) |
Primary citation | Rasouli, A.,Yu, Q.,Dehghani-Ghahnaviyeh, S.,Wen, P.C.,Kowal, J.,Locher, K.P.,Tajkhorshid, E. Differential dynamics and direct interaction of bound ligands with lipids in multidrug transporter ABCG2. Proc.Natl.Acad.Sci.USA, 120:e2213437120-e2213437120, 2023 Cited by PubMed: 36580587DOI: 10.1073/pnas.2213437120 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
Download full validation report