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6S53
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CRYSTAL STRUCTURE OF TRIM21 RING DOMAIN IN COMPLEX WITH AN ISOPEPTIDE-LINKED UBE2N~UBIQUITIN CONJUGATE
Descriptor:Ubiquitin-conjugating enzyme E2 N, Polyubiquitin-C, E3 ubiquitin-protein ligase TRIM21, ...
Authors:Kiss, L., Boland, A., Neuhaus, D., James, L.C.
Deposit date:2019-06-30
Release date:2019-09-11
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A tri-ionic anchor mechanism drives Ube2N-specific recruitment and K63-chain ubiquitination in TRIM ligases.
Nat Commun, 10, 2019
6RH6
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SOLUTION STRUCTURE AND 1H, 13C AND 15N CHEMICAL SHIFT ASSIGNMENTS FOR THE COMPLEX OF NECAP1 PHEAR DOMAIN WITH PHOSPHORYLATED AP2 MU2 148-163
Descriptor:Adaptin ear-binding coat-associated protein 1, AP-2 complex subunit mu
Authors:Owen, D.J., Neuhaus, D., Yang, J.-C., Herrmann, T.
Deposit date:2019-04-18
Release date:2019-09-04
Method:SOLUTION NMR
Cite:Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation.
Dev.Cell, 50, 2019
6RH5
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SOLUTION STRUCTURE AND 1H, 13C AND 15N CHEMICAL SHIFT ASSIGNMENTS FOR NECAP1 PHEAR DOMAIN
Descriptor:Adaptin ear-binding coat-associated protein 1
Authors:Owen, D.J., Neuhaus, D., Yang, J.-C., Herrmann, T.
Deposit date:2019-04-18
Release date:2019-09-04
Method:SOLUTION NMR
Cite:Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation.
Dev.Cell, 50, 2019
6QH7
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AP2 CLATHRIN ADAPTOR MU2T156-PHOSPHORYLATED CORE WITH TWO CARGO PEPTIDES IN OPEN+ CONFORMATION
Descriptor:AP-2 complex subunit alpha, AP-2 complex subunit beta, ADAPTOR-RELATED PROTEIN COMPLEX 2, ...
Authors:Wrobel, A.G., Owen, D.J., McCoy, A.J., Evans, P.R.
Deposit date:2019-01-15
Release date:2019-09-04
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation.
Dev.Cell, 50, 2019
6QH6
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AP2 CLATHRIN ADAPTOR CORE WITH TWO CARGO PEPTIDES IN OPEN+ CONFORMATION
Descriptor:AP-2 complex subunit alpha, AP-2 complex subunit beta, AP-2 complex subunit mu, ...
Authors:Wrobel, A.G., Owen, D.J., McCoy, A.J., Evans, P.R.
Deposit date:2019-01-15
Release date:2019-09-04
Method:X-RAY DIFFRACTION (5 Å)
Cite:Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation.
Dev.Cell, 50, 2019
6QH5
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AP2 CLATHRIN ADAPTOR MU2T156-PHOSPHORYLATED CORE IN CLOSED CONFORMATION
Descriptor:AP-2 complex subunit alpha, AP-2 complex subunit beta, AP-2 complex subunit mu, ...
Authors:Wrobel, A.G., Owen, D.J., McCoy, A.J., Evans, P.R.
Deposit date:2019-01-15
Release date:2019-09-04
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation.
Dev.Cell, 50, 2019
5OLM
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TRIM21
Descriptor:E3 ubiquitin-protein ligase TRIM21, ZINC ION
Authors:James, L.C.
Deposit date:2017-07-28
Release date:2018-04-25
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Intracellular antibody signalling is regulated by phosphorylation of the Fc receptor TRIM21.
Elife, 7, 2018
5NR6
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NMR STRUCTURE AND 1H, 13C AND 15N SIGNAL ASSIGNMENTS FOR DICTYOSTELIUM DISCOIDANS MATB PROTEIN S71A MUTANT
Descriptor:MatB protein
Authors:Neuhaus, D., Hedgethorne, K., Yang, J.-C.
Deposit date:2017-04-22
Release date:2017-09-20
Last modified:2019-05-08
Method:SOLUTION NMR
Cite:Homeodomain-like DNA binding proteins control the haploid-to-diploid transition in Dictyostelium.
Sci Adv, 3, 2017
5NR5
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NMR STRUCTURE AND 1H, 13C AND 15N SIGNAL ASSIGNMENTS FOR DICTYOSTELIUM DISCOIDEUM MATA PROTEIN
Descriptor:MatA protein
Authors:Neuhaus, D., Hedgethorne, K., Yang, J.-C.
Deposit date:2017-04-22
Release date:2017-09-20
Last modified:2019-05-08
Method:SOLUTION NMR
Cite:Homeodomain-like DNA binding proteins control the haploid-to-diploid transition in Dictyostelium.
Sci Adv, 3, 2017
3MSP
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MOTILE MAJOR SPERM PROTEIN (MSP) OF ASCARIS SUUM, NMR, 20 STRUCTURES
Descriptor:MAJOR SPERM PROTEIN
Authors:Haaf, A., Leclaire III, L., Roberts, G., Kent, H.M., Roberts, T.M., Stewart, M., Neuhaus, D.
Deposit date:1998-09-10
Release date:1999-04-20
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the motile major sperm protein (MSP) of Ascaris suum - evidence for two manganese binding sites and the possible role of divalent cations in filament formation.
J.Mol.Biol., 284, 1998
3CW1
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CRYSTAL STRUCTURE OF HUMAN SPLICEOSOMAL U1 SNRNP
Descriptor:U1 snRNA, Small nuclear ribonucleoprotein Sm D3, Small nuclear ribonucleoprotein-associated proteins B and B, ...
Authors:Pomeranz Krummel, D.A., Oubridge, C., Leung, A.K., Li, J., Nagai, K.
Deposit date:2008-04-21
Release date:2009-03-24
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (5.493 Å)
Cite:Crystal structure of human spliceosomal U1 snRNP at 5.5 A resolution.
Nature, 458, 2009
2XTE
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STRUCTURE OF THE TBL1 TETRAMERISATION DOMAIN
Descriptor:F-BOX-LIKE/WD REPEAT-CONTAINING PROTEIN TBL1X
Authors:Oberoi, J., Fairall, L., Watson, P.J., Greenwood, J.A., Schwabe, J.W.R.
Deposit date:2010-10-06
Release date:2011-01-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Structural Basis for the Assembly of the Smrt/Ncor Core Transcriptional Repression Machinery.
Nat.Struct.Mol.Biol., 18, 2011
2XTD
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STRUCTURE OF THE TBL1 TETRAMERISATION DOMAIN
Descriptor:TBL1 F-BOX-LIKE/WD REPEAT-CONTAINING PROTEIN TBL1X
Authors:Oberoi, J., Fairall, L., Watson, P.J., Greenwood, J.A., Schwabe, J.W.R.
Deposit date:2010-10-06
Release date:2011-01-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural Basis for the Assembly of the Smrt/Ncor Core Transcriptional Repression Machinery.
Nat.Struct.Mol.Biol., 18, 2011
2XTC
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STRUCTURE OF THE TBL1 TETRAMERISATION DOMAIN
Descriptor:F-BOX-LIKE/WD REPEAT-CONTAINING PROTEIN TBL1X
Authors:Oberoi, J., Fairall, L., Watson, P.J., Greenwood, J.A., Schwabe, J.W.R.
Deposit date:2010-10-06
Release date:2011-01-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Structural Basis for the Assembly of the Smrt/Ncor Core Transcriptional Repression Machinery.
Nat.Struct.Mol.Biol., 18, 2011
2VRD
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THE STRUCTURE OF THE ZINC FINGER FROM THE HUMAN SPLICEOSOMAL PROTEIN U1C
Descriptor:U1 SMALL NUCLEAR RIBONUCLEOPROTEIN C, ZINC ION
Authors:Muto, Y., Pomeranz-Krummel, D., Oubridge, C., Hernandez, H., Robinson, C., Neuhaus, D., Nagai, K.
Deposit date:2008-03-31
Release date:2008-04-08
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The Structure and Biochemical Properties of the Human Spliceosomal Protein U1C
J.Mol.Biol., 341, 2004
2V75
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N-TERMINAL DOMAIN OF NAB2
Descriptor:NUCLEAR POLYADENYLATED RNA-BINDING PROTEIN NAB2
Authors:Grant, R.P., Marshall, N.J., Stewart, M.
Deposit date:2007-07-26
Release date:2008-01-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of the N-Terminal Mlp1-Binding Domain of the Saccharomyces Cerevisiae Mrna-Binding Protein, Nab2.
J.Mol.Biol., 376, 2008
2N8A
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1H, 13C AND 15N CHEMICAL SHIFT ASSIGNMENTS AND SOLUTION STRUCTURE FOR PARP-1 F1F2 DOMAINS IN COMPLEX WITH A DNA SINGLE-STRAND BREAK
Descriptor:Poly [ADP-ribose] polymerase 1, DNA (45-MER), ZINC ION
Authors:Neuhaus, D., Eustermann, S., Yang, J., Wu, W.
Deposit date:2015-10-08
Release date:2015-12-02
Last modified:2016-10-19
Method:SOLUTION NMR
Cite:Structural Basis of Detection and Signaling of DNA Single-Strand Breaks by Human PARP-1.
Mol.Cell, 60, 2015
2MY1
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SOLUTION STRUCTURE OF BUD31P
Descriptor:Pre-mRNA-splicing factor BUD31, ZINC ION
Authors:van Roon, A.M., Yang, J., Mathieu, D., Bermel, W., Nagai, K., Neuhaus, D.
Deposit date:2015-01-19
Release date:2015-03-11
Last modified:2015-04-22
Method:SOLUTION NMR
Cite:(113) Cd NMR Experiments Reveal an Unusual Metal Cluster in the Solution Structure of the Yeast Splicing Protein Bud31p.
Angew.Chem.Int.Ed.Engl., 54, 2015
2MRB
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THREE-DIMENSIONAL STRUCTURE OF RABBIT LIVER CD-7 METALLOTHIONEIN-2A IN AQUEOUS SOLUTION DETERMINED BY NUCLEAR MAGNETIC RESONANCE
Descriptor:CD7 METALLOTHIONEIN-2A, CADMIUM ION
Authors:Braun, W., Arseniev, A., Schultze, P., Woergoetter, E., Wagner, G., Vasak, M., Kaegi, J.H.R., Wuthrich, K.
Deposit date:1990-05-14
Release date:1991-04-15
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Three-dimensional structure of rabbit liver [Cd7]metallothionein-2a in aqueous solution determined by nuclear magnetic resonance.
J.Mol.Biol., 201, 1988
2LHN
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RNA-BINDING ZINC FINGER PROTEIN
Descriptor:Nuclear polyadenylated RNA-binding protein NAB2, ZINC ION
Authors:Brockmann, C., Neuhaus, D., Stewart, M.
Deposit date:2011-08-12
Release date:2012-06-27
Method:SOLUTION NMR
Cite:Structural Basis for Polyadenosine-RNA Binding by Nab2 Zn Fingers and Its Function in mRNA Nuclear Export.
Structure, 20, 2012
2LD1
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STRUCTURES AND CHEMICAL SHIFT ASSIGNMENTS FOR THE ADD DOMAIN OF THE ATRX PROTEIN
Descriptor:Transcriptional regulator ATRX, ZINC ION
Authors:Neuhaus, D., Yang, J.
Deposit date:2011-05-13
Release date:2011-06-08
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural consequences of disease-causing mutations in the ATRX-DNMT3-DNMT3L (ADD) domain of the chromatin-associated protein ATRX.
Proc.Natl.Acad.Sci.USA, 104, 2007
2LBM
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SOLUTION STRUCTURE OF THE ADD DOMAIN OF ATRX COMPLEXED WITH HISTONE TAIL H3 1-15 K9ME3
Descriptor:Transcriptional regulator ATRX, histone tail H3 K9me3, ZINC ION
Authors:Eustermann, S., Yang, J., Neuhaus, D.
Deposit date:2011-04-08
Release date:2011-06-29
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Combinatorial readout of histone H3 modifications specifies localization of ATRX to heterochromatin
Nat.Struct.Mol.Biol., 2011
2L5G
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CO-ORDINATES AND 1H, 13C AND 15N CHEMICAL SHIFT ASSIGNMENTS FOR THE COMPLEX OF GPS2 53-90 AND SMRT 167-207
Descriptor:G protein pathway suppressor 2, Putative uncharacterized protein NCOR2
Authors:Oberoi, J., Yang, J., Neuhaus, D., Schwabe, J.W.R.
Deposit date:2010-11-01
Release date:2011-02-02
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery.
Nat.Struct.Mol.Biol., 18, 2011
2L31
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HUMAN PARP-1 ZINC FINGER 2
Descriptor:Poly [ADP-ribose] polymerase 1, ZINC ION
Authors:Neuhaus, D., Eustermann, S., Yang, J., Videler, H.
Deposit date:2010-08-30
Release date:2011-02-02
Last modified:2012-01-11
Method:SOLUTION NMR
Cite:The DNA-binding domain of human PARP-1 interacts with DNA single-strand breaks as a monomer through its second zinc finger.
J.Mol.Biol., 407, 2011
2L30
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HUMAN PARP-1 ZINC FINGER 1
Descriptor:Poly [ADP-ribose] polymerase 1, ZINC ION
Authors:Neuhaus, D., Eustermann, S., Yang, J., Videler, H.
Deposit date:2010-08-30
Release date:2011-02-02
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The DNA-binding domain of human PARP-1 interacts with DNA single-strand breaks as a monomer through its second zinc finger.
J.Mol.Biol., 2011
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