2N8A

1H, 13C and 15N chemical shift assignments and solution structure for PARP-1 F1F2 domains in complex with a DNA single-strand break

Summary for 2N8A

DescriptorPoly [ADP-ribose] polymerase 1, DNA (45-MER), ZINC ION (3 entities in total)
Functional Keywordstransferase
Biological sourceHomo sapiens (human)
Cellular locationNucleus P09874
Total number of polymer chains2
Total molecular weight38109.25
Authors
Neuhaus, D.,Eustermann, S.,Yang, J.,Wu, W. (deposition date: 2015-10-08, release date: 2015-12-02, Last modification date: 2016-10-19)
Primary citation
Eustermann, S.,Wu, W.F.,Langelier, M.F.,Yang, J.C.,Easton, L.E.,Riccio, A.A.,Pascal, J.M.,Neuhaus, D.
Structural Basis of Detection and Signaling of DNA Single-Strand Breaks by Human PARP-1.
Mol.Cell, 60:742-754, 2015
PubMed: 26626479 (PDB entries with the same primary citation)
DOI: 10.1016/j.molcel.2015.10.032
MImport into Mendeley
Experimental method
SOLUTION NMR
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Structure validation

ClashscoreRamachandran outliersSidechain outliers200.2%8.0%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures

More Asymmetric unit images

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Molmil generated image of 2n8a
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