8R1X

Solution structure and chemical shift assignments for HMG-D Y12F mutant complexed to a 14:12 dA2 bulge DNA

Replaces:  1E7J

Summary for 8R1X

• Entry DOI: 10.2210/pdb8r1x/pdb
• NMR Information: BMRB: 52208
• Descriptor: High mobility group protein D, DNA (5'-D(*CP*GP*AP*TP*AP*TP*TP*AP*AP*GP*AP*GP*CP*C)-3'), DNA (5'-D(*GP*GP*CP*TP*CP*AP*AP*TP*AP*TP*CP*G)-3') (3 entities in total)
• Functional Keywords: hmg protein, dna-binding protein, protein-dna complex, dna binding protein
• Biological source: Drosophila melanogaster (fruit fly); More
• Total number of polymer chains: 3
• Total formula weight: 20378.16

Authors

Yang, J.C.,Hill, G.R.,Neuhaus, D. (deposition date: 2023-11-02, release date: 2024-09-11)

• Primary citation: Hill, G.,Yang, J.C.,Easton, L.,Cerdan, R.,McLaughlin, S.,Stott, K.,Travers, A.,Neuhaus, D.; A Single Interfacial Point Mutation Rescues Solution Structure Determination of the Complex of HMG-D with a DNA Bulge.; Chembiochem, :e202400395-e202400395, 2024; PubMed: 39145407; DOI: 10.1002/cbic.202400395

Experimental method

SOLUTION NMR