First PBZ domain of human APLF protein in complex with ribofuranosyladenosine

Summary for 2KQD

Related2KQB 2KQC 2KQE
DescriptorAprataxin and PNK-like factor, ZINC ION, ADENOSINE, ... (4 entities in total)
Functional Keywordsadp-ribosylation, dna damage, dna repair, metal-binding, nucleotide-binding, nucleus, zinc, zinc-finger, lyase
Biological sourceHomo sapiens (human)
Cellular locationNucleus Q8IW19
Total number of polymer chains1
Total molecular weight10535.84
Neuhaus, D.,Eustermann, S.,Brockmann, C.,Yang, J. (deposition date: 2009-11-04, release date: 2010-01-19, Last modification date: 2011-07-13)
Primary citation
Eustermann, S.,Brockmann, C.,Mehrotra, P.V.,Yang, J.C.,Loakes, D.,West, S.C.,Ahel, I.,Neuhaus, D.
Solution structures of the two PBZ domains from human APLF and their interaction with poly(ADP-ribose).
Nat.Struct.Mol.Biol., 17:241-243, 2010
PubMed: 20098424 (PDB entries with the same primary citation)
DOI: 10.1038/nsmb.1747
MImport into Mendeley
Experimental method
NMR Information

Structure validation

ClashscoreRamachandran outliersSidechain outliers94.2%14.6%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures
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