3U9H | |
3U9Y | |
3UA9 | |
4HKI | TANKYRASE 2 IN COMPLEX WITH FLAVONE | Descriptor: | Tankyrase-2, ZINC ION, SULFATE ION, ... | Authors: | Narwal, M., Haikarainen, T., Lehtio, L. | Deposit date: | 2012-10-15 | Release date: | 2012-10-31 | Last modified: | 2013-05-22 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Screening and structural analysis of flavones inhibiting tankyrases. J.Med.Chem., 56, 2013
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4HKK | COMPLEX STRUCTURE OF HUMAN TANKYRASE 2 WITH APIGENIN | Descriptor: | Tankyrase-2, ZINC ION, SULFATE ION, ... | Authors: | Narwal, M., Haikarainen, T., Lehtio, L. | Deposit date: | 2012-10-15 | Release date: | 2012-10-31 | Last modified: | 2013-05-22 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Screening and structural analysis of flavones inhibiting tankyrases. J.Med.Chem., 56, 2013
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4HKN | COMPLEX STRUCTURE OF HUMAN TANKYRASE 2 WITH LUTEOLIN | Descriptor: | Tankyrase-2, ZINC ION, SULFATE ION, ... | Authors: | Narwal, M., Haikarainen, T., Lehtio, L. | Deposit date: | 2012-10-15 | Release date: | 2012-10-31 | Last modified: | 2013-05-22 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Screening and structural analysis of flavones inhibiting tankyrases. J.Med.Chem., 56, 2013
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4HL5 | COMPLEX STRUCTURE OF HUMAN TANKYRASE 2 WITH 7-HYDROXY -4'-METHOXYFLAVONE | Descriptor: | Tankyrase-2, SULFATE ION, ZINC ION, ... | Authors: | Narwal, M., Haikarainen, T., Lehtio, L. | Deposit date: | 2012-10-16 | Release date: | 2012-10-31 | Last modified: | 2013-05-22 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Screening and structural analysis of flavones inhibiting tankyrases. J.Med.Chem., 56, 2013
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4HLF | CRYSTAL STRUCTURE OF TANKYRASE 2 IN COMPLEX WITH 7,3',4'-TRIHYDROXYFLAVONE | Descriptor: | Tankyrase-2, ZINC ION, SULFATE ION, ... | Authors: | Narwal, M., Haikarainen, T., Lehtio, L. | Deposit date: | 2012-10-17 | Release date: | 2012-10-31 | Last modified: | 2013-05-22 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Screening and structural analysis of flavones inhibiting tankyrases. J.Med.Chem., 56, 2013
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4HLG | CRYSTAL STRUCTURE OF TANKYRASE 2 IN COMPLEX WITH 3'-HYDROXYFLAVONE | Descriptor: | Tankyrase-2, SULFATE ION, 2-(3-hydroxyphenyl)-4H-chromen-4-one, ... | Authors: | Narwal, M., Haikarainen, T., Lehtio, L. | Deposit date: | 2012-10-17 | Release date: | 2012-10-31 | Last modified: | 2013-05-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Screening and structural analysis of flavones inhibiting tankyrases. J.Med.Chem., 56, 2013
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4HLH | CRYSTAL STRUCTURE OF TANKYRASE 2 IN COMPLEX WITH 4'-FLUOROFLAVONE | Descriptor: | Tankyrase-2, ZINC ION, SULFATE ION, ... | Authors: | Narwal, M., Haikarainen, T., Lehtio, L. | Deposit date: | 2012-10-17 | Release date: | 2012-10-31 | Last modified: | 2013-05-22 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Screening and structural analysis of flavones inhibiting tankyrases. J.Med.Chem., 56, 2013
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4HLK | CRYSTAL STRUCTURE OF TANKYRASE 2 IN COMPLEX WITH 4'-METHYLFLAVONE | Descriptor: | Tankyrase-2, SULFATE ION, 2-(4-methylphenyl)-4H-chromen-4-one, ... | Authors: | Narwal, M., Haikarainen, T., Lehtio, L. | Deposit date: | 2012-10-17 | Release date: | 2012-10-31 | Last modified: | 2013-05-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Screening and structural analysis of flavones inhibiting tankyrases. J.Med.Chem., 56, 2013
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4HLM | CRYSTAL STRUCTURE OF TANKYRASE 2 IN COMPLEX WITH 3',4'-DIHYDROXYFLAVONE | Descriptor: | Tankyrase-2, ZINC ION, SULFATE ION, ... | Authors: | Narwal, M., Haikarainen, T., Lehtio, L. | Deposit date: | 2012-10-17 | Release date: | 2012-10-31 | Last modified: | 2013-05-22 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Screening and structural analysis of flavones inhibiting tankyrases. J.Med.Chem., 56, 2013
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4HMH | CRYSTAL STRUCTURE OF TANKYRASE 2 IN COMPLEX WITH 7,3-DIHYDROXYFLAVONE | Descriptor: | Tankyrase-2, ZINC ION, SULFATE ION, ... | Authors: | Narwal, M., Haikarainen, T., Lehtio, L. | Deposit date: | 2012-10-18 | Release date: | 2012-10-31 | Last modified: | 2013-05-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Screening and structural analysis of flavones inhibiting tankyrases. J.Med.Chem., 56, 2013
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4KZL | CRYSTAL STRUCTURE OF HUMAN TANKYRASE 2 IN COMPLEX WITH 4'-FLUORO FLAVONE | Descriptor: | Tankyrase-2, 2-(4-fluorophenyl)-4H-chromen-4-one, ZINC ION, ... | Authors: | Narwal, M., Haikarainen, T., Lehtio, L. | Deposit date: | 2013-05-30 | Release date: | 2013-10-30 | Last modified: | 2014-01-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Discovery of tankyrase inhibiting flavones with increased potency and isoenzyme selectivity. J.Med.Chem., 56, 2013
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4KZQ | CRYSTAL STRUCTURE OF HUMAN TANKYRASE 2 IN COMPLEX WITH 4' -HYDROXY FLAVONE | Descriptor: | Tankyrase-2, 2-(4-HYDROXY-PHENYL)-CHROMAN-4-ONE, ZINC ION, ... | Authors: | Narwal, M., Haikarainen, T., Lehtio, L. | Deposit date: | 2013-05-30 | Release date: | 2013-10-30 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Discovery of tankyrase inhibiting flavones with increased potency and isoenzyme selectivity. J.Med.Chem., 56, 2013
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4KZU | CRYSTAL STRUCTURE OF HUMAN TANKYRASE 2 IN COMPLEX WITH 4' -BROMO FLAVONE | Descriptor: | Tankyrase-2, 2-(4-bromophenyl)-4H-chromen-4-one, ZINC ION, ... | Authors: | Narwal, M., Haikarainen, T., Lehtio, L. | Deposit date: | 2013-05-30 | Release date: | 2013-10-30 | Last modified: | 2014-01-15 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Discovery of tankyrase inhibiting flavones with increased potency and isoenzyme selectivity. J.Med.Chem., 56, 2013
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4L09 | CRYSTAL STRUCTURE OF HUMAN TANKYRASE 2 IN COMPLEX WITH 4-(4-OXO-4H-CHROMEN-2-YL)BENZOIC ACID | Descriptor: | Tankyrase-2, 4-(4-oxo-4H-chromen-2-yl)benzoic acid, ZINC ION, ... | Authors: | Narwal, M., Haikarainen, T., Lehtio, L. | Deposit date: | 2013-05-31 | Release date: | 2013-10-30 | Last modified: | 2014-01-15 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Discovery of tankyrase inhibiting flavones with increased potency and isoenzyme selectivity. J.Med.Chem., 56, 2013
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4L0B | TANKYRASE 2 IN COMPLEX WITH 4'-DIMETHYLAMINO FLAVONE | Descriptor: | Tankyrase-2, ZINC ION, SULFATE ION, ... | Authors: | Narwal, M., Haikarainen, T., Lehtio, L. | Deposit date: | 2013-05-31 | Release date: | 2013-10-30 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Discovery of tankyrase inhibiting flavones with increased potency and isoenzyme selectivity. J.Med.Chem., 56, 2013
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4L0I | TANKYRASE 2 CATALYTIC DOMAIN IN COMPLEX WITH ETHYL 4-(4-OXO-4H-CHROMEN-2-YL)BENZOATE | Descriptor: | Tankyrase-2, ethyl 4-(4-oxo-4H-chromen-2-yl)benzoate, ZINC ION, ... | Authors: | Narwal, M., Haikarainen, T., Lehtio, L. | Deposit date: | 2013-05-31 | Release date: | 2013-10-30 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Discovery of tankyrase inhibiting flavones with increased potency and isoenzyme selectivity. J.Med.Chem., 56, 2013
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4L0S | TANKYRASE 2 IN COMPLEX WITH 4'-CYANO FLAVONE | Descriptor: | Tankyrase-2, 4-(4-oxo-4H-chromen-2-yl)benzonitrile, ZINC ION, ... | Authors: | Narwal, M., Haikarainen, T., Lehtio, L. | Deposit date: | 2013-06-01 | Release date: | 2013-10-30 | Last modified: | 2014-01-15 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Discovery of tankyrase inhibiting flavones with increased potency and isoenzyme selectivity. J.Med.Chem., 56, 2013
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4L0T | TANKYRASE 2 IN COMPLEX WITH 4'-NITRO FLAVONE | Descriptor: | Tankyrase-2, 2-(4-nitrophenyl)-4H-chromen-4-one, SULFATE ION, ... | Authors: | Narwal, M., Haikarainen, T., Lehtio, L. | Deposit date: | 2013-06-01 | Release date: | 2013-10-30 | Last modified: | 2014-01-15 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Discovery of tankyrase inhibiting flavones with increased potency and isoenzyme selectivity. J.Med.Chem., 56, 2013
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4L0V | TANKYRASE 2 IN COMPLEX WITH 4'-CHLORO FLAVONE | Descriptor: | Tankyrase-2, 2-(4-chlorophenyl)-4H-chromen-4-one, ZINC ION, ... | Authors: | Narwal, M., Haikarainen, T., Lehtio, L. | Deposit date: | 2013-06-01 | Release date: | 2013-10-30 | Last modified: | 2014-01-15 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Discovery of tankyrase inhibiting flavones with increased potency and isoenzyme selectivity. J.Med.Chem., 56, 2013
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4L10 | TANKYRASE 2 IN COMPLEX WITH 4'-METHOXY FLAVONE | Descriptor: | Tankyrase-2, SULFATE ION, ZINC ION, ... | Authors: | Narwal, M., Haikarainen, T., Lehtio, L. | Deposit date: | 2013-06-01 | Release date: | 2013-10-30 | Last modified: | 2014-01-15 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Discovery of tankyrase inhibiting flavones with increased potency and isoenzyme selectivity. J.Med.Chem., 56, 2013
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4L2F | TANKYRASE 2 IN COMPLEX WITH 6-CHLORO FLAVONE | Descriptor: | Tankyrase-2, 6-chloro-2-phenyl-4H-chromen-4-one, ZINC ION, ... | Authors: | Narwal, M., Haikarainen, T., Lehtio, L. | Deposit date: | 2013-06-04 | Release date: | 2013-10-30 | Last modified: | 2014-01-15 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Discovery of tankyrase inhibiting flavones with increased potency and isoenzyme selectivity. J.Med.Chem., 56, 2013
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4L2G | TANKYRASE 2 IN COMPLEX WITH 6- FLUORO FLAVONE | Descriptor: | Tankyrase-2, SULFATE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Narwal, M., Haikarainen, T., Lehtio, L. | Deposit date: | 2013-06-04 | Release date: | 2013-10-30 | Last modified: | 2014-01-15 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Discovery of tankyrase inhibiting flavones with increased potency and isoenzyme selectivity. J.Med.Chem., 56, 2013
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