Complex structure of human tankyrase 2 with nicotinamide

Summary for 3U9H

DescriptorTankyrase-2, ZINC ION, SULFATE ION, ... (7 entities in total)
Functional Keywordsprotein-ligand complex, diphtheria toxin like fold, transferase, adp-ribosylation
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm Q9H2K2
Total number of polymer chains2
Total molecular weight55663.18
Narwal, M.,Lehtio, L. (deposition date: 2011-10-19, release date: 2011-11-02, Last modification date: 2012-02-22)
Primary citation
Narwal, M.,Venkannagari, H.,Lehtio, L.
Structural basis of selective inhibition of human tankyrases.
J.Med.Chem., 55:1360-1367, 2012
PubMed: 22233320 (PDB entries with the same primary citation)
DOI: 10.1021/jm201510p
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.201300.8%2.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report