5MZF

Crystal structure of dog MTH1 protein

Summary for 5MZF

Entry DOI	10.2210/pdb5mzf/pdb
Descriptor	MTH1 protein, SULFATE ION, ACETATE ION, ... (6 entities in total)
Functional Keywords	hydrolase, drug target
Biological source	Canis lupus familiaris (Dog)
Total number of polymer chains	4
Total formula weight	82522.57
Authors	Narwal, M.,Jemth, A.-S.,Helleday, T.,Stenmark, P. (deposition date: 2017-01-31, release date: 2018-01-10, Last modification date: 2024-01-17)
Primary citation	Narwal, M.,Jemth, A.S.,Gustafsson, R.,Almlof, I.,Warpman Berglund, U.,Helleday, T.,Stenmark, P. Crystal Structures and Inhibitor Interactions of Mouse and Dog MTH1 Reveal Species-Specific Differences in Affinity. Biochemistry, 57:593-603, 2018 Cited by PubMed: 29281266 DOI: 10.1021/acs.biochem.7b01163 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation