Author results

4Z9E
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ALBA FROM THERMOPLASMA VOLCANIUM
Descriptor:DNA/RNA-binding protein Alba
Authors:Ma, C., Lee, S.J., Pathak, C., Lee, B.J.
Deposit date:2015-04-10
Release date:2016-02-24
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Alba from Thermoplasma volcanium belongs to alpha-NAT's: An insight into the structural aspects of Tv Alba and its acetylation by Tv Ard1.
Arch.Biochem.Biophys., 590, 2016
4PV6
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CRYSTAL STRUCTURE ANALYSIS OF ARD1 FROM THERMOPLASMA VOLCANIUM
Descriptor:N-terminal acetyltransferase complex subunit [ARD1], ACETYL COENZYME *A, COENZYME A
Authors:Ma, C., Lee, S.J., Lee, B.J.
Deposit date:2014-03-15
Release date:2015-01-21
Method:X-RAY DIFFRACTION (3.32 Å)
Cite:Structure of Thermoplasma volcanium Ard1 belongs to N-acetyltransferase family member suggesting multiple ligand binding modes with acetyl coenzyme A and coenzyme A.
Biochim.Biophys.Acta, 1844, 2014
6K6U
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CRYSTAL STRUCTURE OF THE HUMAN YTHDC2 YTH DOMAIN
Descriptor:3'-5' RNA helicase YTHDC2
Authors:Ma, C., Liao, S., Xu, C.
Deposit date:2019-06-04
Release date:2019-12-25
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Crystal structure of human YTHDC2 YTH domain.
Biochem.Biophys.Res.Commun., 518, 2019
2L2I
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NMR STRUCTURE OF THE COMPLEX BETWEEN THE TFB1 SUBUNIT OF TFIIH AND THE ACTIVATION DOMAIN OF EKLF
Descriptor:RNA polymerase II transcription factor B subunit 1, Krueppel-like factor 1
Authors:Mas, C., Di Lello, P., Lafrance-Vanasse, J., Omichinski, J.G.
Deposit date:2010-08-18
Release date:2011-07-06
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR Structure of the complex between the Tfb1 subunit of TFIIH and the activation domain of EKLF
To be Published
4PQO
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STRUCTURE OF THE HUMAN SNX14 PX DOMAIN IN SPACE GROUP I41
Descriptor:Sorting nexin-14
Authors:Mas, C., Norwood, S., Bugarcic, A., Kinna, G., Leneva, N., Kovtun, O., Teasdale, R., Collins, B.
Deposit date:2014-03-03
Release date:2014-09-03
Last modified:2014-10-29
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural Basis for Different Phosphoinositide Specificities of the PX Domains of Sorting Nexins Regulating G-protein Signaling.
J.Biol.Chem., 289, 2014
4PQP
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CRYSTAL STRUCTURE OF HUMAN SNX14 PX DOMAIN IN SPACE GROUP P43212
Descriptor:Sorting nexin-14, GLYCEROL
Authors:Mas, C., Norwood, S., Bugarcic, A., Kinna, G., Leneva, N., Kovtun, O., Teasdale, R., Collins, B.
Deposit date:2014-03-03
Release date:2014-09-03
Last modified:2014-10-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Basis for Different Phosphoinositide Specificities of the PX Domains of Sorting Nexins Regulating G-protein Signaling.
J.Biol.Chem., 289, 2014
5H4P
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STRUCTURAL SNAPSHOT OF CYTOPLASMIC PRE-60S RIBOSOMAL PARTICLES BOUND WITH NMD3, LSG1, TIF6 AND REH1
Descriptor:25S ribosomal RNA, 5S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Ma, C., Wu, S., Li, N., Chen, Y., Yan, K., Li, Z., Zheng, L., Lei, J., Woolford, J.L., Gao, N.
Deposit date:2016-11-01
Release date:2017-01-25
Last modified:2017-06-14
Method:ELECTRON MICROSCOPY (3.07 Å)
Cite:Structural snapshot of cytoplasmic pre-60S ribosomal particles bound by Nmd3, Lsg1, Tif6 and Reh1
Nat. Struct. Mol. Biol., 24, 2017
5H5U
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MECHANISTIC INSIGHTS INTO THE ALTERNATIVE TRANSLATION TERMINATION BY ARFA AND RF2
Descriptor:30S ribosomal protein S20, 30S ribosomal protein S21, Alternative ribosome-rescue factor A, ...
Authors:Ma, C., Kurita, D., Li, N., Chen, Y., Himeno, H., Gao, N.
Deposit date:2016-11-09
Release date:2017-01-25
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Mechanistic insights into the alternative translation termination by ArfA and RF2
Nature, 541, 2017
2KI2
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SOLUTION STRUCTURE OF SS-DNA BINDING PROTEIN 12RNP2 PRECURSOR, HP0827(O25501_HELPY) FORM HELICOBACTER PYLORI
Descriptor:Ss-DNA binding protein 12RNP2
Authors:Ma, C., Lee, J., Kim, J., Park, S., Kwon, A., Lee, B.
Deposit date:2009-04-20
Release date:2009-10-20
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR solution structure of HP0827 (O25501_HELPY) from Helicobacter pylori: model of the possible RNA-binding site
J.Biochem., 146, 2009
6WTT
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CRYSTALS STRUCTURE OF THE SARS-COV-2 (COVID-19) MAIN PROTEASE WITH INHIBITOR GC-376
Descriptor:3C-like proteinase, (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, DI(HYDROXYETHYL)ETHER, ...
Authors:Sacco, M., Ma, C., Chen, Y., Wang, J.
Deposit date:2020-05-03
Release date:2020-05-20
Last modified:2020-07-01
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease.
Cell Res., 2020
6XBG
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CRYSTAL STRUCTURE OF THE SARS-COV-2 (COVID-19) MAIN PROTEASE IN COMPLEX WITH INHIBITOR UAW246
Descriptor:main protease, inhibitor UAW246, GLYCEROL, ...
Authors:Sacco, M., Ma, C., Wang, J., Chen, Y.
Deposit date:2020-06-05
Release date:2020-06-17
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with inhibitor UAW246
To Be Published
6XBH
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CRYSTAL STRUCTURE OF THE SARS-COV-2 (COVID-19) MAIN PROTEASE IN COMPLEX WITH INHIBITOR UAW247
Descriptor:main protease, inhibitor UAW247, GLYCEROL, ...
Authors:Sacco, M., Ma, C., Wang, J., Chen, Y.
Deposit date:2020-06-06
Release date:2020-06-17
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with inhibitor UAW247
To Be Published
6XBI
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CRYSTAL STRUCTURE OF THE SARS-COV-2 (COVID-19) MAIN PROTEASE IN COMPLEX WITH INHIBITOR UAW248
Descriptor:main protease, inhibitor UAW248, GLYCEROL, ...
Authors:Sacco, M., Ma, C., Wang, J., Chen, Y.
Deposit date:2020-06-06
Release date:2020-06-17
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with inhibitor UAW248
To Be Published
6GZ8
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FIRST GERMN DOMAIN OF THE SPORULATION PROTEIN GERM FROM BACILLUS SUBTILIS
Descriptor:Spore germination protein GerM, SODIUM ION, 1,2-ETHANEDIOL
Authors:Trouve, J., Mohamed, A., Leisico, F., Contreras-Martel, C., Liu, B., Mas, C., Rudner, D.Z., Rodrigues, C.D.A., Morlot, C.
Deposit date:2018-07-03
Release date:2018-10-10
Last modified:2018-12-26
Method:X-RAY DIFFRACTION (1 Å)
Cite:Structural characterization of the sporulation protein GerM from Bacillus subtilis.
J. Struct. Biol., 204, 2018
6GZB
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TANDEM GERMN DOMAINS OF THE SPORULATION PROTEIN GERM FROM BACILLUS SUBTILIS
Descriptor:Spore germination protein GerM, ACETATE ION, 1,2-ETHANEDIOL
Authors:Trouve, J., Mohamed, A., Leisico, F., Contreras-Martel, C., Liu, B., Mas, C., Rudner, D.Z., Rodrigues, C.D.A., Morlot, C.
Deposit date:2018-07-03
Release date:2018-10-10
Last modified:2019-10-02
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural characterization of the sporulation protein GerM from Bacillus subtilis.
J. Struct. Biol., 204, 2018
2K2U
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NMR STRUCTURE OF THE COMPLEX BETWEEN TFB1 SUBUNIT OF TFIIH AND THE ACTIVATION DOMAIN OF VP16
Descriptor:RNA polymerase II transcription factor B subunit 1, Alpha trans-inducing protein
Authors:Langlois, C., Mas, C., Di Lello, P., Miller Jenkins, P.M., Legault, J., Omichinski, J.G.
Deposit date:2008-04-11
Release date:2008-08-12
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR Structure of the Complex between the Tfb1 Subunit of TFIIH and the Activation Domain of VP16: Structural Similarities between VP16 and p53.
J.Am.Chem.Soc., 130, 2008
2OAZ
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HUMAN METHIONINE AMINOPEPTIDASE-2 COMPLEXED WITH SB-587094
Descriptor:human Methionine Amino Peptidase 2, COBALT (II) ION, N-(2-ISOPROPYLPHENYL)-3-[(2-THIENYLMETHYL)THIO]-1H-1,2,4-TRIAZOL-5-AMINE
Authors:Marino Jr., J.P., Fisher, P.W., Hofmann, G.A., Kirkpatrick, R., Janson, C.A., Johnson, R.K., Ma, C., Mattern, M., Meek, T.D., Ryan, D., Schulz, C., Smith, W.W., Tew, D.G., Tomazek Jr., T.A., Veber, D.F., Xiong, W.C., Yamamoto, Y., Yamashita, K., Yang, G., Thompson, S.K.
Deposit date:2006-12-18
Release date:2007-06-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Highly potent inhibitors of methionine aminopeptidase-2 based on a 1,2,4-triazole pharmacophore.
J.Med.Chem., 50, 2007
2XA8
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CRYSTAL STRUCTURE OF THE FAB DOMAIN OF OMALIZUMAB AT 2.41A
Descriptor:OMALIZUMAB HEAVY CHAIN, OMALIZUMAB LIGHT CHAIN
Authors:Huang, C.H., Hung, F.H.A., Lim, C., Chang, T.W., Ma, C.
Deposit date:2010-03-30
Release date:2011-05-11
Last modified:2019-09-18
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Structural and Physical Basis for Anti-IgE Therapy.
Sci Rep, 5, 2015
3PFT
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CRYSTAL STRUCTURE OF UNTAGGED C54A MUTANT FLAVIN REDUCTASE (DSZD) IN COMPLEX WITH FMN FROM MYCOBACTERIUM GOODII
Descriptor:Flavin reductase, FLAVIN MONONUCLEOTIDE
Authors:Li, Q., Xu, P., Ma, C., Gu, L., Liu, X., Zhang, C., Li, N., Su, J., Li, B., Liu, S.
Deposit date:2010-10-29
Release date:2011-11-02
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.601 Å)
Cite:The flavin reductase DSZD from a desulfurizing mycobacterium goodii strain: systemic manipulation and investigation based on the crystal structure
To be Published
6JPM
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CRYSTAL STRUCTURE OF ODORANT BINDING PROTEIN 4 IN THE NATURAL PREDATOR CHRYSOPA PALLENS
Descriptor:Odorant binding protein 4
Authors:Li, T.T., Ma, C.
Deposit date:2019-03-27
Release date:2019-10-16
Last modified:2019-10-30
Method:X-RAY DIFFRACTION (2.098 Å)
Cite:Crystal structure and ligand identification of odorant binding protein 4 in the natural predator Chrysopa pallens.
Int.J.Biol.Macromol., 141, 2019
1ZXO
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X-RAY CRYSTAL STRUCTURE OF PROTEIN Q8A1P1 FROM BACTEROIDES THETAIOTAOMICRON. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET BTR25.
Descriptor:conserved hypothetical protein Q8A1P1
Authors:Kuzin, A.P., Yong, W., Forouhar, F., Vorobiev, S., Xiao, R., Ma, C., Acton, T., Montelione, G.T., Hunt, J., Tong, L., Northeast Structural Genomics Consortium (NESG)
Deposit date:2005-06-08
Release date:2005-07-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:X-Ray structure of the hypothetical protein Q8A1P1 at the resolution 3.2A. Northeast Structural Genomics Consortium target BtR25.
To be Published
2AJA
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X-RAY STRUCTURE OF AN ANKYRIN REPEAT FAMILY PROTEIN Q5ZSV0 FROM LEGIONELLA PNEUMOPHILA. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET LGR21.
Descriptor:ankyrin repeat family protein
Authors:Kuzin, A.P., Chen, Y., Acton, T., Xiao, R., Conover, K., Ma, C., Kellie, R., Montelione, G.T., Tong, L., Hunt, J.F., Northeast Structural Genomics Consortium (NESG)
Deposit date:2005-08-01
Release date:2005-08-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:X-Ray structure of an ankyrin repeat family protein Q5ZSV0 from Legionella pneumophila.
To be Published
3FWL
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CRYSTAL STRUCTURE OF THE FULL-LENGTH TRANSGLYCOSYLASE PBP1B FROM ESCHERICHIA COLI
Descriptor:Penicillin-binding protein 1B, MOENOMYCIN
Authors:Sung, M.T., Lai, Y.T., Huang, C.Y., Chou, L.Y., Wong, C.H., Ma, C.
Deposit date:2009-01-19
Release date:2009-06-02
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (3.086 Å)
Cite:Crystal structure of the membrane-bound bifunctional transglycosylase PBP1b from Escherichia coli.
Proc.Natl.Acad.Sci.USA, 106, 2009
3J3V
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ATOMIC MODEL OF THE IMMATURE 50S SUBUNIT FROM BACILLUS SUBTILIS (STATE I-A)
Descriptor:50S ribosomal protein L32, 50S ribosomal protein L34, 50S ribosomal protein L1, ...
Authors:Li, N., Guo, Q., Zhang, Y., Yuan, Y., Ma, C., Lei, J., Gao, N.
Deposit date:2013-04-28
Release date:2013-06-12
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (13.3 Å)
Cite:Cryo-EM structures of the late-stage assembly intermediates of the bacterial 50S ribosomal subunit
Nucleic Acids Res., 41, 2013
3J3W
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ATOMIC MODEL OF THE IMMATURE 50S SUBUNIT FROM BACILLUS SUBTILIS (STATE II-A)
Descriptor:ribosome RNA 23S, 50S ribosomal protein L32, 50S ribosomal protein L2, ...
Authors:Li, N., Guo, Q., Zhang, Y., Yuan, Y., Ma, C., Lei, J., Gao, N.
Deposit date:2013-04-28
Release date:2013-06-12
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (10.7 Å)
Cite:Cryo-EM structures of the late-stage assembly intermediates of the bacterial 50S ribosomal subunit
Nucleic Acids Res., 41, 2013