4Y21

Crystal Structure of Munc13-1 MUN domain

Summary for 4Y21

Entry DOI	10.2210/pdb4y21/pdb
Descriptor	Protein unc-13 homolog A (1 entity in total)
Functional Keywords	helical bundles, catchr, exocytosis
Biological source	Rattus norvegicus (Rat)
Cellular location	Cytoplasm: Q62768
Total number of polymer chains	1
Total formula weight	61987.02
Authors	Yang, X.Y.,Wang, S.,Sheng, Y.,Zhang, M.,Zou, W.J.,Wu, L.J.,Kang, L.J.,Rizo, J.,Zhang, R.G.,Xu, T.,Ma, C. (deposition date: 2015-02-09, release date: 2015-06-10, Last modification date: 2023-11-08)
Primary citation	Yang, X.,Wang, S.,Sheng, Y.,Zhang, M.,Zou, W.,Wu, L.,Kang, L.,Rizo, J.,Zhang, R.,Xu, T.,Ma, C. Syntaxin opening by the MUN domain underlies the function of Munc13 in synaptic-vesicle priming. Nat.Struct.Mol.Biol., 22:547-554, 2015 Cited by PubMed: 26030875 DOI: 10.1038/nsmb.3038 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation