Author results

3E2I
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CRYSTAL STRUCTURE OF THYMIDINE KINASE FROM S. AUREUS
Descriptor:Thymidine kinase, ZINC ION, GLYCEROL
Authors:Lam, R., Johns, K., Battaile, K.P., Romanov, V., Lam, K., Pai, E.F., Chirgadze, N.Y.
Deposit date:2008-08-05
Release date:2009-08-11
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Crystal structure of Thymidine Kinase from S. aureus
To be Published
3P8A
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CRYSTAL STRUCTURE OF A HYPOTHETICAL PROTEIN FROM STAPHYLOCOCCUS AUREUS
Descriptor:uncharacterized protein, GLYCEROL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
Authors:Lam, R., Qiu, W., Battaile, K., Lam, K., Romanov, V., Chan, T., Pai, E., Chirgadze, N.Y.
Deposit date:2010-10-13
Release date:2011-10-19
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal Structure of a hypothetical protein from Staphylococcus aureus
To be Published
4PAV
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STRUCTURE OF HYPOTHETICAL PROTEIN SA1046 FROM S. AUREUS.
Descriptor:Glyoxalase family protein
Authors:Battaile, K.P., Mulichak, A., Lam, R., Lam, K., Soloveychik, M., Romanov, V., Jones, K., Pai, E.F., Chirgadze, N.Y.
Deposit date:2014-04-10
Release date:2015-05-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of hypothetical protein SA1046 from S. aureus.
To Be Published
4PAW
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STRUCTURE OF HYPOTHETICAL PROTEIN HP1257.
Descriptor:Orotate phosphoribosyltransferase, ZINC ION, PHOSPHATE ION, ...
Authors:Battaile, K.P., Lam, R., Lam, K., Romanov, V., Jones, K., Soloveychik, M., Pai, E.F., Chirgadze, N.Y.
Deposit date:2014-04-10
Release date:2015-05-06
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Structure of hypothetical protein HP1257.
To Be Published
3D7R
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CRYSTAL STRUCTURE OF A PUTATIVE ESTERASE FROM STAPHYLOCOCCUS AUREUS
Descriptor:Esterase, BROMIDE ION, CHLORIDE ION, ...
Authors:Lam, R., Battaile, K.P., Chan, T., Romanov, V., Lam, K., Soloveychik, M., Wu-Brown, J., Pai, E.F., Chirgadze, N.Y.
Deposit date:2008-05-21
Release date:2009-06-09
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Crystal structure of a putative esterase from Staphylococcus aureus
To be Published
3K2A
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CRYSTAL STRUCTURE OF THE HOMEOBOX DOMAIN OF HUMAN HOMEOBOX PROTEIN MEIS2
Descriptor:Homeobox protein Meis2, CHLORIDE ION, ACETATE ION
Authors:Lam, R., Soloveychik, M., Battaile, K.P., Romanov, V., Lam, K., Beletskaya, I., Gordon, E., Pai, E.F., Chirgadze, N.Y.
Deposit date:2009-09-29
Release date:2010-10-13
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of the homeobox domain of human homeobox protein Meis2
To be Published
3KOR
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CRYSTAL STRUCTURE OF A PUTATIVE TRP REPRESSOR FROM STAPHYLOCOCCUS AUREUS
Descriptor:Possible Trp repressor
Authors:Lam, R., Vodsedalek, J., Lam, K., Romanov, V., Battaile, K.P., Beletskaya, I., Pai, E.F., Chirgadze, N.Y.
Deposit date:2009-11-13
Release date:2010-11-17
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of a putative Trp repressor from Staphylococcus aureus
To be Published
3KWL
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CRYSTAL STRUCTURE OF A HYPOTHETICAL PROTEIN FROM HELICOBACTER PYLORI
Descriptor:uncharacterized protein
Authors:Lam, R., Thompson, C.M., Vodsedalek, J., Lam, K., Romanov, V., Battaile, K.P., Beletskaya, I., Gordon, E., Pai, E.F., Chirgadze, N.Y.
Deposit date:2009-12-01
Release date:2010-12-01
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Crystal structure of a hypothetical protein from Helicobacter pylori
To be Published
3L5A
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CRYSTAL STRUCTURE OF A PROBABLE NADH-DEPENDENT FLAVIN OXIDOREDUCTASE FROM STAPHYLOCOCCUS AUREUS
Descriptor:NADH/flavin oxidoreductase/NADH oxidase, TRIETHYLENE GLYCOL
Authors:Lam, R., Gordon, R.D., Vodsedalek, J., Battaile, K.P., Grebemeskel, S., Lam, K., Romanov, V., Chan, T., Mihajlovic, V., Thompson, C.M., Guthrie, J., Pai, E.F., Chirgadze, N.Y.
Deposit date:2009-12-21
Release date:2010-12-22
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure of a probable NADH-dependent flavin oxidoreductase from Staphylococcus aureus
To be Published
3NUR
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CRYSTAL STRUCTURE OF A PUTATIVE AMIDOHYDROLASE FROM STAPHYLOCOCCUS AUREUS
Descriptor:Amidohydrolase, CALCIUM ION
Authors:Qiu, W., Lam, R., Romanov, V., Lam, K., Soloveychik, M., Pai, E.F., Chirgadze, N.Y.
Deposit date:2010-07-07
Release date:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of a putative amidohydrolase from Staphylococcus aureus
To be Published
3P8K
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CRYSTAL STRUCTURE OF A PUTATIVE CARBON-NITROGEN FAMILY HYDROLASE FROM STAPHYLOCOCCUS AUREUS
Descriptor:Hydrolase, carbon-nitrogen family, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
Authors:Gordon, R.D., Qiu, W., Battaile, K., Lam, K., Soloveychik, M., Benetteraj, D., Romanov, V., Pai, E.F., Chirgadze, N.Y.
Deposit date:2010-10-14
Release date:2011-10-19
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of carbon-nitrogen family hydrolase from Staphylococcus aureus
To be Published
4GWF
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CRYSTAL STRUCTURE OF THE TYROSINE PHOSPHATASE SHP-2 WITH Y279C MUTATION
Descriptor:Tyrosine-protein phosphatase non-receptor type 11, 1,2-ETHANEDIOL, GLYCEROL, ...
Authors:Qiu, W., Lin, A., Hutchinson, A., Romanov, V., Ruzanov, M., Thompson, C., Lam, K., Kisselman, G., Battaile, K., Chirgadze, N.Y.
Deposit date:2012-09-03
Release date:2013-09-04
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the tyrosine phosphatase SHP-2 with Y279C mutation
TO BE PUBLISHED
4H1O
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CRYSTAL STRUCTURE OF THE TYROSINE PHOSPHATASE SHP-2 WITH D61G MUTATION
Descriptor:Tyrosine-protein phosphatase non-receptor type 11, 1,2-ETHANEDIOL
Authors:Qiu, W., Lin, A., Hutchinson, A., Romanov, V., Ruzanov, M., Thompson, C., Lam, K., Kisselman, G., Battaile, K., Chirgadze, N.Y.
Deposit date:2012-09-11
Release date:2013-09-11
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the tyrosine phosphatase SHP-2 with D61G mutation
To be Published
4H34
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CRYSTAL STRUCTURE OF THE TYROSINE PHOSPHATASE SHP-2 WITH Q506P MUTATION
Descriptor:Tyrosine-protein phosphatase non-receptor type 11, 1,2-ETHANEDIOL, GLYCEROL
Authors:Qiu, W., Lin, A., Hutchinson, A., Romanov, V., Ruzanov, M., Thompson, C., Lam, K., Kisselman, G., Battaile, K., Chirgadze, N.Y.
Deposit date:2012-09-13
Release date:2013-10-02
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of the tyrosine phosphatase SHP-2 with Q506P mutation
To be Published
4NWF
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CRYSTAL STRUCTURE OF THE TYROSINE PHOSPHATASE SHP-2 WITH N308D MUTATION
Descriptor:Tyrosine-protein phosphatase non-receptor type 11, 1,2-ETHANEDIOL, GLYCEROL
Authors:Qiu, W., Lin, A., Hutchinson, A., Romanov, V., Ruzanov, M., Thompson, C., Lam, K., Kisselman, G., Battalie, K., Chirgadze, N.Y.
Deposit date:2013-12-06
Release date:2014-12-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the tyrosine phosphatase SHP-2 with N308D mutation
To be Published
4NWG
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CRYSTAL STRUCTURE OF THE TYROSINE PHOSPHATASE SHP-2 WITH E139D MUTATION
Descriptor:Tyrosine-protein phosphatase non-receptor type 11, 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ...
Authors:Qiu, W., Lin, A., Hutchinson, A., Romanov, V., Ruzanov, M., Thompson, C., Lam, K., Kisselman, G., Battalie, K., Chirgadze, N.Y.
Deposit date:2013-12-06
Release date:2014-12-10
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal structure of the tyrosine phosphatase SHP-2 with E139D mutation
To be Published
5WIX
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CRYSTAL STRUCTURE OF P47 OF CLOSTRIDIUM BOTULINUM E1
Descriptor:p-47 protein
Authors:Lam, K., Liu, S., Qi, R., Jin, R.
Deposit date:2017-07-20
Release date:2017-10-25
Last modified:2018-05-02
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The hypothetical protein P47 of Clostridium botulinum E1 strain Beluga has a structural topology similar to bactericidal/permeability-increasing protein.
Toxicon, 147, 2018
6DKK
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STRUCTURE OF BONT
Descriptor:Botulinum neurotoxin type A, PHOSPHATE ION
Authors:Lam, K., Jin, R.
Deposit date:2018-05-29
Release date:2018-12-26
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A viral-fusion-peptide-like molecular switch drives membrane insertion of botulinum neurotoxin A1.
Nat Commun, 9, 2018
6MHJ
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STRUCTURE OF BONT MUTANT
Descriptor:Botulinum neurotoxin type A, PHOSPHATE ION
Authors:Lam, K., Jin, R.
Deposit date:2018-09-18
Release date:2018-12-26
Method:X-RAY DIFFRACTION (3.019 Å)
Cite:A viral-fusion-peptide-like molecular switch drives membrane insertion of botulinum neurotoxin A1.
Nat Commun, 9, 2018
3L20
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CRYSTAL STRUCTURE OF A HYPOTHETICAL PROTEIN FROM STAPHYLOCOCCUS AUREUS
Descriptor:Putative uncharacterized protein
Authors:Lam, R., Chan, T., Battaile, K.P., Mihajlovic, V., Romanov, V., Soloveychik, M., Kisselman, G., McGrath, T.E., Lam, K., Pai, E.F., Chirgadze, N.Y.
Deposit date:2009-12-14
Release date:2010-10-27
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.451 Å)
Cite:Crystal structure of a hypothetical protein from Staphylococcus aureus
To be Published
5JLV
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RECEPTOR BINDING DOMAIN OF BOTULINUM NEUROTOXIN A IN COMPLEX WITH HUMAN GLYCOSYLATED SV2C
Descriptor:Botulinum neurotoxin type A, Synaptic vesicle glycoprotein 2C, ACETATE ION, ...
Authors:Yao, G., Zhang, S., Mahrhold, S., Lam, K., Stern, D., Bagramyan, K., Perry, K., Kalkum, M., Rummel, A., Dong, M., Jin, R.
Deposit date:2016-04-27
Release date:2016-06-15
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A.
Nat.Struct.Mol.Biol., 23, 2016
5JMC
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RECEPTOR BINDING DOMAIN OF BOTULINUM NEUROTOXIN A IN COMPLEX WITH RAT SV2C
Descriptor:Botulinum neurotoxin type A, Synaptic vesicle glycoprotein 2C
Authors:Yao, G., Zhang, S., Mahrhold, S., Lam, K., Stern, D., Bagramyan, K., Perry, K., Kalkum, M., Rummel, A., Dong, M., Jin, R.
Deposit date:2016-04-28
Release date:2016-06-15
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A.
Nat.Struct.Mol.Biol., 23, 2016
5BP5
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CRYSTAL STRUCTURE OF HA17-HA33-IPT
Descriptor:HA-33, HA-17, ISOPROPYL-1-BETA-D-THIOGALACTOSIDE
Authors:Lee, K., Lam, K., Jin, R.
Deposit date:2015-05-27
Release date:2015-09-02
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Inhibiting oral intoxication of botulinum neurotoxin A complex by carbohydrate receptor mimics.
Toxicon, 107, 2015
5BQU
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CRYSTAL STRUCTURE OF HA17-HA33-LACTULOSE
Descriptor:HA-33, HA-17, FRUCTOSE, ...
Authors:Lee, K., Lam, K., Jin, R.
Deposit date:2015-05-29
Release date:2015-10-14
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Inhibiting oral intoxication of botulinum neurotoxin A complex by carbohydrate receptor mimics.
Toxicon, 107, 2015
6BVD
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STRUCTURE OF BOTULINUM NEUROTOXIN SEROTYPE HA LIGHT CHAIN
Descriptor:Light Chain, CALCIUM ION, ACETATE ION, ...
Authors:Jin, R., Lam, K.
Deposit date:2017-12-12
Release date:2018-05-09
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Structural and biochemical characterization of the protease domain of the mosaic botulinum neurotoxin type HA.
Pathog Dis, 76, 2018
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